proxymetacaine has been researched along with Dry Eye Syndromes in 4 studies
proxymetacaine: RN given refers to parent cpd; structure
Dry Eye Syndromes: Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Morphine attenuated spontaneous blinking, and the response to hypertonic saline in dry eye animals and topical proparacaine application reduced spontaneous blinking down to control levels." | 3.81 | Corneal sensitivity following lacrimal gland excision in the rat. ( Barton, ST; Kurose, M; Mecum, NE; Meng, ID, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Forristal, MT | 1 |
| Stephenson, KAJ | 1 |
| Bayraktutar, BN | 1 |
| Hamrah, P | 1 |
| Meng, ID | 1 |
| Barton, ST | 1 |
| Mecum, NE | 1 |
| Kurose, M | 1 |
| Crane, AM | 1 |
| Feuer, W | 1 |
| Felix, ER | 1 |
| Levitt, RC | 1 |
| McClellan, AL | 1 |
| Sarantopoulos, KD | 1 |
| Galor, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Trigeminal Nerve Stimulation on Subbasal Corneal Nerve Plexus Density and Chronic Ocular Pain in Patients With Dry Eye[NCT04648085] | 7 participants (Actual) | Interventional | 2021-02-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for proxymetacaine and Dry Eye Syndromes
| Article | Year |
|---|---|
Differentiating primary dry eye disease from ocular neuropathic pain: implications for symptom management.
Topics: Dry Eye Syndromes; Eye Pain; Humans; Neuralgia; Tears; Vision, Ocular | 2023 |
Response to McMonnies and Young Re: "ISOPT Clinical Hot Topic Panel Discussion on Cornea Anterior Segment Disease" by Asbell et al. (
Topics: Anesthetics, Local; Anterior Eye Segment; Cornea; Corneal Diseases; Diagnosis, Differential; Dry Eye | 2020 |
Corneal sensitivity following lacrimal gland excision in the rat.
Topics: Analgesics, Opioid; Analysis of Variance; Anesthetics, Local; Animals; Blinking; Cornea; Disease Mod | 2015 |
Evidence of central sensitisation in those with dry eye symptoms and neuropathic-like ocular pain complaints: incomplete response to topical anaesthesia and generalised heightened sensitivity to evoked pain.
Topics: Anesthesia, Local; Anesthetics, Local; Biomarkers; Cornea; Cranial Nerve Diseases; Cross-Sectional S | 2017 |