Page last updated: 2024-11-03

proxymetacaine and Bacterial Eye Infections

proxymetacaine has been researched along with Bacterial Eye Infections in 5 studies

proxymetacaine: RN given refers to parent cpd; structure

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Reynolds, MM1
Mercill, SL1
Wirkus, AL1
Greenwood Quaintance, K1
Pulido, JS1
Rautenbach, P1
Wilson, A1
Gouws, P1
Yap, YC1
Smith, M1
Byles, D1
Segarra, S1
Papasouliotis, K1
Helps, C1
Oguz, H1
Oguz, E1
Karadede, S1
Aslan, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections[NCT02951351]36 participants (Actual)Interventional2016-10-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Comfort With Intravitreal Injection Standard Procedure

Subjects were asked to complete a survey about their experience with intravitreal injections after the procedure was completed. The survey was scored on a 0 to 10 numeric rating scale (NRS) where 0 was a positive response and 10 was a negative response. The lower the score, the more comfortable the subject was with the procedure, the higher the score, the less comfortable the subject was with the procedure. (NCT02951351)
Timeframe: post-injection

Interventionscore on a scale (Median)
Standard Procedure + Culture0
Proparacaine + Culture0

Expectation Intravitreal Injection Will Have Negative Consequences on Subject Health

Subjects were asked to complete a survey about their experience with intravitreal injections after the procedure was completed. The survey was scored on a 0 to 10 numeric rating scale (NRS) where 0 was a positive response and 10 was a negative response. A lower score indicated subjects did not expect the injection would negatively affect their overall health. Higher scores indicated subjects expected the injection would negatively affect their overall health. (NCT02951351)
Timeframe: post-injection

Interventionscore on a scale (Median)
Standard Procedure + Culture0
Proparacaine + Culture0

Expectation the Injection Will Contribute to Curing/Improving Eye Condition

Patients were asked to rate their expectation on the extent to which the intravitreal injections would contribute to curing or improving their eye condition. The question was scored on a 0 to 10 numeric rating scale (NRS) where 0 was a negative response (not at all) and 10 was a positive response (to a large extent). A low score indicated the subject did not expect the injection would contribute to curing or improving the eye condition while a high score indicated the subject did expect the injection will help to cure or improve the eye condition. (NCT02951351)
Timeframe: post-injection

Interventionscore on a scale (Median)
Standard Procedure + Culture8
Proparacaine + Culture10

Impression of Pre-injection Preparations

Subjects were asked to complete a survey about their experience with intravitreal injections after the procedure was completed. The survey consisted of 6 questions and was scored on a 0 to 10 numeric rating scale (NRS) where 0 was a positive response and 10 was a negative response. The lower the score, the more positive impression of the preparation process, the higher the score, the less positive impression of the preparation process.. (NCT02951351)
Timeframe: post-injection

Interventionscore on a scale (Median)
Standard Procedure + Culture0
Proparacaine + Culture0

Number of Study Participants With Positive Conjunctival Culture

Conjunctival samples were collected after participants received either an additional drop of proparacaine or povidone iodine. Bacterial cultures were performed from conjunctival samples by the Mayo Clinic Microbiology laboratory. Bacterial species identification was performed on any and all bacteria that grew. (NCT02951351)
Timeframe: pre-injection

InterventionParticipants (Count of Participants)
Standard Procedure + Culture1
Proparacaine + Culture1

Overall Impression of Visit for Intravitreal Injection

Subjects were asked to complete a survey about their experience with intravitreal injections after the procedure was completed. The survey was scored on a 0 to 10 numeric rating scale (NRS) where 0 was a positive response and 10 was a negative response. The lower the score, the more positive impression of the visit, the higher the score, the less positive impression of the visit. (NCT02951351)
Timeframe: post-injection

Interventionscore on a scale (Median)
Standard Procedure + Culture0
Proparacaine + Culture0

Pain at the Time of Injection

Subjects were asked to complete a survey about their experience with intravitreal injections after the procedure was completed. The survey was scored on a 0 to 10 numeric rating scale (NRS) where 0 was a positive response and 10 was a negative response. The lower the score, the lesser the perceived pain, the higher the score, the higher the perceived pain. (NCT02951351)
Timeframe: post-injection

Interventionscore on a scale (Median)
Standard Procedure + Culture2
Proparacaine + Culture1

Residual Pain From Intravitreal Injection

Subjects were asked to complete a survey about their experience with intravitreal injections after the procedure was completed. The survey was scored on a 0 to 10 numeric rating scale (NRS) where 0 was a positive response and 10 was a negative response. The lower the score, the lesser the residual pain, the higher the score, the higher the residual pain. (NCT02951351)
Timeframe: post-injection

Interventionscore on a scale (Median)
Standard Procedure + Culture1
Proparacaine + Culture0

Trials

2 trials available for proxymetacaine and Bacterial Eye Infections

ArticleYear
Topical proparacaine eye drops to improve the experience of patients undergoing intravitreal injections: A randomized controlled trial.
    European journal of ophthalmology, 2020, Volume: 30, Issue:6

    Topics: Aged; Aged, 80 and over; Anesthetics, Local; Endophthalmitis; Eye Infections, Bacterial; Female; Hum

2020
The antibacterial effect of topical anesthetic proparacaine on conjunctival flora.
    International ophthalmology, 1999, Volume: 23, Issue:2

    Topics: Aged; Anesthetics, Local; Cataract Extraction; Conjunctiva; Eye Infections, Bacterial; Female; Human

1999

Other Studies

3 other studies available for proxymetacaine and Bacterial Eye Infections

ArticleYear
The reuse of opthalmic Minims: an unacceptable cross-infection risk?
    Eye (London, England), 2010, Volume: 24, Issue:1

    Topics: Corynebacterium; Cross Infection; Culture Media; Disposable Equipment; Drug Contamination; Equipment

2010
The reuse of ophthalmic minims: an unacceptable cross-infection risk?
    Eye (London, England), 2010, Volume: 24, Issue:8

    Topics: Cross Infection; Disposable Equipment; Drug Contamination; Equipment Reuse; Eye Infections, Bacteria

2010
The in vitro effects of proxymetacaine, fluorescein, and fusidic acid on real-time PCR assays used for the diagnosis of Feline herpesvirus 1 and Chlamydophila felis infections.
    Veterinary ophthalmology, 2011, Volume: 14 Suppl 1

    Topics: Alphaherpesvirinae; Anesthetics, Local; Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Chlamydo

2011