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protriptyline and Sleep Apnea Syndromes

protriptyline has been researched along with Sleep Apnea Syndromes in 36 studies

Protriptyline: Tricyclic antidepressant similar in action and side effects to IMIPRAMINE. It may produce excitation.

Sleep Apnea Syndromes: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.

Research Excerpts

ExcerptRelevanceReference
"Fluoxetine was better tolerated than protriptyline."2.67Response of obstructive sleep apnea to fluoxetine and protriptyline. ( Hanzel, DA; Hudgel, DW; Proia, NG, 1991)
"Although the obstructive sleep apnea was not resolved, it was reduced."2.65Protriptyline in obstructive sleep apnea: a double-blind trial. ( Acres, JC; Brownell, LG; Kryger, MH; Sweatman, P; West, P, 1982)
"Nocturnal respiratory failure may occur in patients with the postpolio syndrome, amyotrophic lateral sclerosis, myasthenia gravis, myotonic dystrophy, and muscular dystrophy."2.40Nocturnal respiratory failure as an indication of noninvasive ventilation in the patient with neuromuscular disease. ( Barthlen, GM, 1997)
"The sleep apnea syndromes have attracted the interest of physicians and scientists in many different disciplines because the disorders involve the physiology of sleep, the control of respiration, the function of the upper airway, and the clinical sequelae upon cardiac, pulmonary, and psychological function."2.37Pathophysiology and treatment of sleep apnea. ( Gee, JB; Ingbar, DH, 1985)
"Progress in the diagnosis of sleep disorders gradually led to successful diagnosis-based treatment."1.27Three simultaneous major sleep disorders. ( Douglass, AB; Hays, P, 1987)
"Imipramine treatment was attempted for nonoverweight patients with negative ear, nose and throat (ENT) findings and for patients who had not responded to weight reduction or ENT surgery (in all patients the apneas were not considered life threatening)."1.27Preliminary clinical experience with imipramine HCl in the treatment of sleep apnea syndrome. ( Alroy, GG; Lavie, P; Peled, R; Rubin, AH, 1986)
"The prevalence of sleep apnea was studied in 46 middle- and older-aged men with "essential hypertension."1.27Undiagnosed sleep apnea in patients with essential hypertension. ( DeBehnke, RD; Fletcher, EC; Gorin, AB; Lovoi, MS, 1985)
"Snoring has been shown to be the primary sign of a potentially serious medical condition, ie, obstructive sleep apnea."1.27Diagnosis and management of obstructive sleep apnea. Part II. ( Moran, WB; Orr, WC, 1985)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199027 (75.00)18.7374
1990's9 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dolly, FR1
Wynne, JW1
Gotfried, MH1
Quan, SF1
Clark, RW2
Schmidt, HS1
Schuller, DE1
Brownell, LG1
West, P1
Sweatman, P1
Acres, JC1
Kryger, MH2
Goldstein, JA1
Boudoulas, H1
Schmidt, H1
Geleris, P1
Lewis, RP1
Smith, PL1
Haponik, EF1
Allen, RP1
Bleecker, ER1
Conway, WA2
Zorick, F1
Piccione, P1
Roth, T2
Hochman, MS1
Chediak, AD1
Ziffer, JA1
Thornton, WK1
Roberts, DH1
Lévy, P1
Pépin, JL1
Mayer, P1
Wuyam, B1
Veale, D1
Barthlen, GM1
Montserrat, JM1
Amilibia, J1
Barbé, F1
Capote, F1
Durán, J1
Mangado, NG1
Jiménez, A1
Marín, JM1
Masa, F1
Teran, J1
Hanzel, DA1
Proia, NG1
Hudgel, DW1
Kaufmann, U1
Dorow, P1
Thalhofer, S1
Krieger, J1
Imbs, JL1
Mendelson, WB1
Cherniack, NS1
Fairbanks, DN1
Kuriyama, T1
Tojima, H1
Lombard, RM1
Zwillich, CW3
Robinson, RW2
Nino-Murcia, G1
Bliwise, D1
Keenan, S1
Feibusch, K1
Whyte, KF1
Gould, GA1
Airlie, MA1
Shapiro, CM1
Douglas, NJ1
Stepanski, EJ1
Young, DK1
Zorick, FJ1
Wittig, RM1
Weaver, T1
Millman, RP1
Cunha, UV1
Douglass, AB1
Hays, P1
White, DP1
Guilleminault, C1
Ingbar, DH1
Gee, JB1
Waldhorn, RE1
Rubin, AH1
Alroy, GG1
Peled, R1
Lavie, P1
Fletcher, EC1
DeBehnke, RD1
Lovoi, MS1
Gorin, AB1
Moran, WB1
Orr, WC1

Reviews

9 reviews available for protriptyline and Sleep Apnea Syndromes

ArticleYear
Obstructive sleep apnea-pathogenesis and treatment.
    Lung, 1984, Volume: 162, Issue:1

    Topics: Body Weight; Humans; Male; Oxygen; Positive-Pressure Respiration; Protriptyline; Sleep Apnea Syndrom

1984
Nonsurgical management of the obstructive sleep apnea patient.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1996, Volume: 54, Issue:9

    Topics: Antidepressive Agents, Tricyclic; Bronchodilator Agents; Humans; Occlusal Splints; Positive-Pressure

1996
Management of simple snoring, upper airway resistance syndrome, and moderate sleep apnea syndrome.
    Sleep, 1996, Volume: 19, Issue:9 Suppl

    Topics: Airway Obstruction; Airway Resistance; Humans; Orthodontic Appliances, Removable; Positive-Pressure

1996
Nocturnal respiratory failure as an indication of noninvasive ventilation in the patient with neuromuscular disease.
    Respiration; international review of thoracic diseases, 1997, Volume: 64 Suppl 1

    Topics: Adrenergic Uptake Inhibitors; Amyotrophic Lateral Sclerosis; Cyanosis; Headache; Humans; Hypertensio

1997
[Drug therapy of sleep-related respiration disorders].
    Pneumologie (Stuttgart, Germany), 1991, Volume: 45 Suppl 1

    Topics: Carbonic Anhydrase Inhibitors; Humans; Medroxyprogesterone; Protriptyline; Sleep Apnea Syndromes; Th

1991
[Role of sleep apnea in essential arterial hypertension].
    Presse medicale (Paris, France : 1983), 1990, Nov-24, Volume: 19, Issue:39

    Topics: Atrial Natriuretic Factor; Catecholamines; Humans; Hypertension; Positive-Pressure Respiration; Prev

1990
Clinical neuropharmacology of sleep.
    Neurologic clinics, 1990, Volume: 8, Issue:1

    Topics: Alzheimer Disease; Antidepressive Agents, Tricyclic; Autonomic Nervous System; Diagnosis, Differenti

1990
Medical therapy of obstructive sleep apnea.
    The Medical clinics of North America, 1985, Volume: 69, Issue:6

    Topics: Almitrine; Central Nervous System Stimulants; Diet, Reducing; Humans; Intubation; Male; Naloxone; Na

1985
Pathophysiology and treatment of sleep apnea.
    Annual review of medicine, 1985, Volume: 36

    Topics: Airway Resistance; Aminophylline; Arrhythmias, Cardiac; Electromyography; Humans; Hypertension; Hypo

1985

Trials

4 trials available for protriptyline and Sleep Apnea Syndromes

ArticleYear
Protriptyline in obstructive sleep apnea: a double-blind trial.
    The New England journal of medicine, 1982, Oct-21, Volume: 307, Issue:17

    Topics: Adult; Clinical Trials as Topic; Dibenzocycloheptenes; Double-Blind Method; Heart Rate; Humans; Male

1982
Response of obstructive sleep apnea to fluoxetine and protriptyline.
    Chest, 1991, Volume: 100, Issue:2

    Topics: Adult; Aged; Arousal; Female; Fluoxetine; Humans; Male; Middle Aged; Oxygen Consumption; Prospective

1991
Role of protriptyline and acetazolamide in the sleep apnea/hypopnea syndrome.
    Sleep, 1988, Volume: 11, Issue:5

    Topics: Acetazolamide; Adult; Aged; Clinical Trials as Topic; Dibenzocycloheptenes; Double-Blind Method; Fem

1988
A double-blind trial of protriptyline in the treatment of sleep apnea syndrome.
    Henry Ford Hospital medical journal, 1988, Volume: 36, Issue:1

    Topics: Adult; Clinical Trials as Topic; Dibenzocycloheptenes; Double-Blind Method; Humans; Male; Middle Age

1988

Other Studies

23 other studies available for protriptyline and Sleep Apnea Syndromes

ArticleYear
To sleep, perchance to breathe...
    Lancet (London, England), 1981, Sep-26, Volume: 2, Issue:8248

    Topics: Adult; Female; Humans; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Protriptyline; Respir

1981
Respiratory disorders associated with sleep.
    Comprehensive therapy, 1982, Volume: 8, Issue:9

    Topics: Humans; Lung Diseases, Obstructive; Medroxyprogesterone; Medroxyprogesterone Acetate; Oxygen Inhalat

1982
Sleep-induced ventilatory dysfunction in Down's syndrome.
    Archives of internal medicine, 1980, Volume: 140, Issue:1

    Topics: Adolescent; Adult; Airway Obstruction; Braces; Cheyne-Stokes Respiration; Down Syndrome; Humans; Mal

1980
Sleep apnea.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:10

    Topics: Humans; Protriptyline; Sleep Apnea Syndromes; Tracheotomy

1983
Possible therapy for snoring.
    The Western journal of medicine, 1983, Volume: 138, Issue:2

    Topics: Dibenzocycloheptenes; Humans; Protriptyline; Respiratory Sounds; Sleep Apnea Syndromes; Snoring

1983
Case reports on deterioration of sleep apnea during therapy with propranolol - preliminary studies.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 39, Issue:1

    Topics: Adult; Electroencephalography; Humans; Male; Middle Aged; Propranolol; Protriptyline; Sleep Apnea Sy

1983
The effects of protriptyline in sleep-disordered breathing.
    The American review of respiratory disease, 1983, Volume: 127, Issue:1

    Topics: Adult; Dibenzocycloheptenes; Female; Humans; Male; Middle Aged; Protriptyline; Respiratory Function

1983
Protriptyline in the treatment of sleep apnoea.
    Thorax, 1982, Volume: 37, Issue:1

    Topics: Adult; Dibenzocycloheptenes; Humans; Male; Middle Aged; Protriptyline; Sleep Apnea Syndromes

1982
Hyperekplexia: report of a nonfamilial adult onset case associated with obstructive sleep apnea and abnormal brain nuclear tomography.
    Sleep, 1994, Volume: 17, Issue:3

    Topics: Brain; Carotid Artery, Internal; Clonazepam; Electroencephalography; Evoked Potentials, Somatosensor

1994
[Treatment of sleep apnea-hypoapnea syndrome].
    Archivos de bronconeumologia, 1998, Volume: 34, Issue:4

    Topics: Adrenergic Uptake Inhibitors; Antidepressive Agents, Tricyclic; Humans; Medroxyprogesterone; Positiv

1998
Breathing disorders during sleep.
    Hospital practice (Office ed.), 1986, Feb-15, Volume: 21, Issue:2

    Topics: Arousal; Body Weight; Chemoreceptor Cells; Humans; Nasal Decongestants; Oxygen Inhalation Therapy; P

1986
Nonsurgical treatment of snoring and obstructive sleep apnea.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1989, Volume: 100, Issue:6

    Topics: Humans; Positive-Pressure Respiration; Posture; Protriptyline; Self Care; Sleep Apnea Syndromes; Sno

1989
[Drug therapy of respiratory disturbances during sleep].
    Kokyu to junkan. Respiration & circulation, 1989, Volume: 37, Issue:1

    Topics: Acetazolamide; Humans; Progesterone; Protriptyline; Sleep Apnea Syndromes; Theophylline

1989
The effect of drugs on breathing during sleep.
    Clinics in chest medicine, 1985, Volume: 6, Issue:4

    Topics: Almitrine; Anesthetics; Dose-Response Relationship, Drug; Ethanol; Humans; Hypnotics and Sedatives;

1985
Treatment of obstructive sleep apnea with CPAP and protriptyline.
    Chest, 1988, Volume: 94, Issue:6

    Topics: Dibenzocycloheptenes; Humans; Positive-Pressure Respiration; Protriptyline; Sleep Apnea Syndromes

1988
Broken sleep.
    The American journal of nursing, 1986, Volume: 86, Issue:2

    Topics: Humans; Medroxyprogesterone; Oxygen; Palate, Soft; Pharynx; Positive-Pressure Respiration; Protripty

1986
Antidepressants: their uses in nonpsychiatric disorders of aging.
    Geriatrics, 1986, Volume: 41, Issue:10

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr

1986
Three simultaneous major sleep disorders.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1987, Volume: 32, Issue:1

    Topics: Adult; Depressive Disorder; Female; Humans; Myoclonus; Narcolepsy; Protriptyline; Sleep Apnea Syndro

1987
Sleep and respiration: a postscript.
    Clinics in chest medicine, 1985, Volume: 6, Issue:4

    Topics: Acetazolamide; Airway Obstruction; Airway Resistance; Alcohol Drinking; Combined Modality Therapy; H

1985
Sleep apnea syndrome.
    American family physician, 1985, Volume: 32, Issue:3

    Topics: Acetazolamide; Adult; Diagnosis, Differential; Electrocardiography; Electroencephalography; Electroo

1985
Preliminary clinical experience with imipramine HCl in the treatment of sleep apnea syndrome.
    European neurology, 1986, Volume: 25, Issue:2

    Topics: Adult; Body Weight; Female; Follow-Up Studies; Humans; Imipramine; Male; Middle Aged; Protriptyline;

1986
Undiagnosed sleep apnea in patients with essential hypertension.
    Annals of internal medicine, 1985, Volume: 103, Issue:2

    Topics: Adult; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Monitoring, Physiologic; Palate;

1985
Diagnosis and management of obstructive sleep apnea. Part II.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1985, Volume: 111, Issue:10

    Topics: Adult; Arrhythmias, Cardiac; Body Weight; Electrocardiography; Equipment and Supplies; Humans; Hyoid

1985