protriptyline has been researched along with Pain in 4 studies
Protriptyline: Tricyclic antidepressant similar in action and side effects to IMIPRAMINE. It may produce excitation.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In protriptyline (25 mg/kg) pretreated rats stereotactic 5,7-dihydroxytryptamine (5,7-DHT) lesions of the medial plus laternal 5-hydroxytryptamine (5-HE) bundles in the mesencephalon increased the 5-HT fluorescence in these bundles, and reduced the in vitro uptake of [3H] 5-HT in the hypothalamus to 16% of control values after 2 mug 5,7-DHT/4mul and 12% after 4 mug 5,7-DHT/4mul, and in the cortex cerebri to 35 and 34% of control values, respectively." | 1.26 | Behavioral effects of 5, 7-dihydroxytryptamine lesions of ascending 5-hydroxytryptamine pathways. ( Fuxe, K; Hole, K; Jonsson, G, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Altenbach, RJ | 2 |
| Carr, TL | 2 |
| Chandran, P | 1 |
| Hsieh, GC | 2 |
| Lewis, LG | 1 |
| Manelli, AM | 2 |
| Milicic, I | 1 |
| Marsh, KC | 2 |
| Miller, TR | 1 |
| Strakhova, MI | 2 |
| Vortherms, TA | 1 |
| Wakefield, BD | 1 |
| Wetter, JM | 2 |
| Witte, DG | 1 |
| Honore, P | 2 |
| Esbenshade, TA | 1 |
| Brioni, JD | 2 |
| Cowart, MD | 2 |
| Black, LA | 1 |
| Wensink, EJ | 1 |
| Garrison, TR | 1 |
| Hole, K | 1 |
| Fuxe, K | 1 |
| Jonsson, G | 1 |
| Cunha, UV | 1 |
4 other studies available for protriptyline and Pain
| Article | Year |
|---|---|
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; | 2008 |
Diaryldiamines with dual inhibition of the histamine H(3) receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain.
Topics: Animals; Histamine H3 Antagonists; Naphthols; Norepinephrine Plasma Membrane Transport Proteins; Ost | 2010 |
Behavioral effects of 5, 7-dihydroxytryptamine lesions of ascending 5-hydroxytryptamine pathways.
Topics: Afferent Pathways; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Cerebral Cortex; Huma | 1976 |
Antidepressants: their uses in nonpsychiatric disorders of aging.
Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depr | 1986 |