protoporphyrin ix has been researched along with Prostatic Neoplasms in 27 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Prostatic Neoplasms: Tumors or cancer of the PROSTATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Photodynamic therapy is a promising cancer therapy modality but its application for deep-seated tumor is mainly hindered by the shallow penetration of visible light." | 1.48 | Development of a functionalized UV-emitting nanocomposite for the treatment of cancer using indirect photodynamic therapy. ( Arellano, DL; Chauhan, K; Fournier, PGJ; Hirata, GA; Jain, A; Juárez, P; Sengar, P; Verdugo-Meza, A, 2018) |
| "Here we created uniformly sized PC-3 prostate cancer spheroids using a 3D culture plate (EZSPHERE)." | 1.43 | Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy. ( Hagiya, Y; Inoue, K; Kobayashi, T; Matsumoto, K; Nakajima, M; Nakayama, T; Ogura, SI; Okajima, H; Otsuka, S; Shuin, T; Tanaka, T, 2016) |
| "Past attempts at detecting prostate cancer (PCa) cells in voided urine by traditional cytology have been impeded by undesirably low sensitivities but high specificities." | 1.40 | Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Hirayama, A; Kuwada, M; Miyake, M; Nakai, Y; Tanaka, N; Yoshida, K, 2014) |
| " Lastly, cell uptake study and PET image-based pharmacokinetic analyses of the PPIX-PEG6-BBN analog were carried out in a human prostate cancer cell line, PC-3, which highly expresses the GRP receptor, and PC-3 tumor-bearing mice." | 1.39 | The synthesis of 64Cu-chelated porphyrin photosensitizers and their tumor-targeting peptide conjugates for the evaluation of target cell uptake and PET image-based pharmacokinetics of targeted photodynamic therapy agents. ( Mukai, H; Wada, Y; Watanabe, Y, 2013) |
| "The prostate and breast cancer cell lines were investigated: MCF-7, a human breast cancer responsive to androgen therapy; MDA-MB231, a more aggressive human breast cancer non-responsive to androgen therapy; LNCaP, a lymphonodal metastasis of prostate carcinoma responsive to androgen therapy; DU-145, a human prostate cancer non-responsive to androgen therapy." | 1.37 | Inhibition of cell growth induced by photosensitizer PP(Arg)2-mediated photodynamic therapy in human breast and prostate cell lines. Part I. ( Małecki, M; Nowak-Stępniowska, A; Padzik-Graczyk, A; Romiszewska, A; Wiktorska, K, 2011) |
| "Prostate cancer is one of the most common types of cancer in men, and unfortunately many prostate tumours remain asymptomatic until they reach advanced stages." | 1.36 | Intrinsic fluorescence of protoporphyrin IX from blood samples can yield information on the growth of prostate tumours. ( Bellini, MH; Courrol, LC; de Oliveira Silva, FR; Schor, N; Tristão, VR; Vieira, ND, 2010) |
| "Human prostate cancer (DU-145) and squamous carcinoma (A431) cells were used as experimental model." | 1.35 | Diamino acid derivatives of PpIX as potential photosensitizers for photodynamic therapy of squamous cell carcinoma and prostate cancer: in vitro studies. ( Glosnicka, R; Graczyk, A; Juzeniene, A; Kwitniewski, M; Ma, LW; Moan, J, 2009) |
| " Searching for new approaches, we tested a known inducer of cellular differentiation, methotrexate (MTX), in combination with ALA-PDT in LNCaP cells." | 1.33 | Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells. ( Anand, S; Chang, Y; Hasan, T; Mai, Z; Maytin, EV; Ortel, BJ; Sinha, AK, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 19 (70.37) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sengar, P | 1 |
| Juárez, P | 1 |
| Verdugo-Meza, A | 1 |
| Arellano, DL | 1 |
| Jain, A | 1 |
| Chauhan, K | 1 |
| Hirata, GA | 1 |
| Fournier, PGJ | 1 |
| Nakai, Y | 2 |
| Miyake, M | 2 |
| Anai, S | 2 |
| Hori, S | 1 |
| Tatsumi, Y | 1 |
| Morizawa, Y | 1 |
| Onisi, S | 1 |
| Tanaka, N | 2 |
| Fujimoto, K | 2 |
| Mukai, H | 1 |
| Wada, Y | 1 |
| Watanabe, Y | 1 |
| Bozzini, G | 1 |
| Colin, P | 1 |
| Betrouni, N | 1 |
| Maurage, CA | 1 |
| Leroy, X | 1 |
| Simonin, S | 1 |
| Martin-Schmitt, C | 1 |
| Villers, A | 1 |
| Mordon, S | 1 |
| Fukuhara, H | 1 |
| Inoue, K | 2 |
| Kurabayashi, A | 1 |
| Furihata, M | 1 |
| Fujita, H | 1 |
| Utsumi, K | 1 |
| Sasaki, J | 1 |
| Shuin, T | 2 |
| Yamauchi, M | 1 |
| Honda, N | 1 |
| Hazama, H | 1 |
| Tachikawa, S | 1 |
| Nakamura, H | 1 |
| Kaneda, Y | 1 |
| Awazu, K | 1 |
| Kuwada, M | 1 |
| Chihara, Y | 1 |
| Hirayama, A | 1 |
| Yoshida, K | 1 |
| Hirao, Y | 1 |
| Fahey, JM | 2 |
| Girotti, AW | 2 |
| Bui, B | 2 |
| Liu, L | 1 |
| Chen, W | 2 |
| Homayoni, H | 1 |
| Ma, L | 1 |
| Zhang, J | 1 |
| Sahi, SK | 1 |
| Rashidi, LH | 1 |
| Nakayama, T | 1 |
| Otsuka, S | 1 |
| Kobayashi, T | 1 |
| Okajima, H | 1 |
| Matsumoto, K | 1 |
| Hagiya, Y | 1 |
| Nakajima, M | 1 |
| Tanaka, T | 1 |
| Ogura, SI | 1 |
| Bazak, J | 1 |
| Wawak, K | 1 |
| Korytowski, W | 1 |
| Fidanzi-Dugas, C | 1 |
| Liagre, B | 1 |
| Chemin, G | 1 |
| Perraud, A | 1 |
| Carrion, C | 1 |
| Couquet, CY | 1 |
| Granet, R | 1 |
| Sol, V | 1 |
| Léger, DY | 1 |
| Kwitniewski, M | 1 |
| Juzeniene, A | 1 |
| Ma, LW | 1 |
| Glosnicka, R | 1 |
| Graczyk, A | 1 |
| Moan, J | 1 |
| de Oliveira Silva, FR | 1 |
| Bellini, MH | 3 |
| Tristão, VR | 1 |
| Schor, N | 3 |
| Vieira, ND | 3 |
| Courrol, LC | 3 |
| Silva, FR | 2 |
| Nabeshima, CT | 2 |
| Nowak-Stępniowska, A | 2 |
| Małecki, M | 2 |
| Wiktorska, K | 2 |
| Romiszewska, A | 2 |
| Padzik-Graczyk, A | 2 |
| Teper, E | 1 |
| Makhov, P | 1 |
| Golovine, K | 1 |
| Canter, DJ | 1 |
| Myers, CB | 1 |
| Kutikov, A | 1 |
| Sterious, SN | 1 |
| Uzzo, RG | 1 |
| Kolenko, VM | 1 |
| Ortel, B | 1 |
| Sharlin, D | 1 |
| O'Donnell, D | 1 |
| Sinha, AK | 2 |
| Maytin, EV | 2 |
| Hasan, T | 3 |
| Zaak, D | 1 |
| Sroka, R | 1 |
| Stocker, S | 1 |
| Bise, K | 1 |
| Lein, M | 1 |
| Höppner, M | 1 |
| Frimberger, D | 1 |
| Schneede, P | 1 |
| Reich, O | 1 |
| Kriegmair, M | 1 |
| Knüchel, R | 1 |
| Baumgartner, R | 1 |
| Hofstetter, A | 1 |
| Anand, S | 1 |
| Ortel, BJ | 1 |
| Chang, Y | 1 |
| Mai, Z | 1 |
| Bogaards, A | 1 |
| Sterenborg, HJ | 1 |
| Trachtenberg, J | 1 |
| Wilson, BC | 1 |
| Lilge, L | 1 |
| Chang, SC | 1 |
| Buonaccorsi, GA | 1 |
| MacRobert, AJ | 1 |
| Bown, SG | 1 |
| Momma, T | 1 |
| Hamblin, MR | 1 |
| Chakrabarti, P | 1 |
| Orihuela, E | 1 |
| Egger, N | 1 |
| Neal, DE | 1 |
| Gangula, R | 1 |
| Adesokun, A | 1 |
| Motamedi, M | 1 |
27 other studies available for protoporphyrin ix and Prostatic Neoplasms
| Article | Year |
|---|---|
Development of a functionalized UV-emitting nanocomposite for the treatment of cancer using indirect photodynamic therapy.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Female; Folic Acid; Luminescent Agents; Male; Mice; Nan | 2018 |
Spectrophotometric photodynamic diagnosis of prostate cancer cells excreted in voided urine using 5-aminolevulinic acid.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Area Under Curve; Biomarkers, Tumor; Biopsy; Ce | 2018 |
The synthesis of 64Cu-chelated porphyrin photosensitizers and their tumor-targeting peptide conjugates for the evaluation of target cell uptake and PET image-based pharmacokinetics of targeted photodynamic therapy agents.
Topics: Amino Acid Sequence; Animals; Biological Transport; Bombesin; Cell Line, Tumor; Chelating Agents; Co | 2013 |
Efficiency of 5-ALA mediated photodynamic therapy on hypoxic prostate cancer: a preclinical study on the Dunning R3327-AT2 rat tumor model.
Topics: Aminolevulinic Acid; Animals; Cell Hypoxia; Cell Line, Tumor; Drug Evaluation, Preclinical; Drug The | 2013 |
The inhibition of ferrochelatase enhances 5-aminolevulinic acid-based photodynamic action for prostate cancer.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Line, Tumor; Chloroquine; Deferoxamine; Drug Synergism | 2013 |
A novel photodynamic therapy for drug-resistant prostate cancer cells using porphyrus envelope as a novel photosensitizer.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Drug Delivery Systems; Humans; Male; Photochemotherapy; Photo | 2014 |
Photodynamic diagnosis of shed prostate cancer cells in voided urine treated with 5-aminolevulinic acid.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Biomarkers, Tumor; Feasibility Studies; Humans; Male; | 2014 |
Accelerated migration and invasion of prostate cancer cells after a photodynamic therapy-like challenge: Role of nitric oxide.
Topics: Cell Line, Tumor; Cell Movement; Humans; Male; Neoplasm Invasiveness; Nitric Oxide; Nitric Oxide Syn | 2015 |
Latex carrier for improving protoporphyrin IX for photodynamic therapy.
Topics: Cell Line, Tumor; Cell Survival; Drug Stability; Humans; Hydrogen Bonding; Latex; Male; Molecular St | 2016 |
Synthesis and conjugation of Sr
Topics: Adsorption; Cell Line, Tumor; Cell Survival; Drug Compounding; Humans; Male; Metal Nanoparticles; Na | 2016 |
Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Hu | 2016 |
Enhanced aggressiveness of bystander cells in an anti-tumor photodynamic therapy model: Role of nitric oxide produced by targeted cells.
Topics: Amidines; Apoptosis; Benzoates; Benzylamines; Bystander Effect; Cell Line, Tumor; Cell Movement; Cel | 2017 |
Analysis of the in vitro and in vivo effects of photodynamic therapy on prostate cancer by using new photosensitizers, protoporphyrin IX-polyamine derivatives.
Topics: Animals; Apoptosis; Cell Line, Tumor; CHO Cells; Cricetulus; Humans; Male; Photochemotherapy; Photos | 2017 |
Diamino acid derivatives of PpIX as potential photosensitizers for photodynamic therapy of squamous cell carcinoma and prostate cancer: in vitro studies.
Topics: Amino Acids, Diamino; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Screening Assays, Antitumor; | 2009 |
Intrinsic fluorescence of protoporphyrin IX from blood samples can yield information on the growth of prostate tumours.
Topics: Animals; Biomarkers, Tumor; Calibration; Fluorescence; Humans; Male; Mice; Mice, Nude; Prostatic Neo | 2010 |
Enhancement of blood porphyrin emission intensity with aminolevulinic acid administration: a new concept for photodynamic diagnosis of early prostate cancer.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Cell Line, Tumor; Drug Synergism; Drug Therapy, | 2011 |
Inhibition of cell growth induced by photosensitizer PP(Arg)2-mediated photodynamic therapy in human breast and prostate cell lines. Part I.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Female; Hu | 2011 |
Cytotoxicity of PP(Arg)(2)- and Hp(Arg)(2)-mediated photodynamic therapy and early stage of apoptosis induction in prostate carcinoma in vitro.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Darkness; Hematoporphyrins; Humans; Male; Membrane Poten | 2011 |
The effect of 5-aminolevulinic acid and its derivatives on protoporphyrin IX accumulation and apoptotic cell death in castrate-resistant prostate cancer cells.
Topics: Aminolevulinic Acid; Apoptosis; Cell Line, Tumor; Chelating Agents; Ethylenediamines; Humans; Male; | 2012 |
Study of protoporphyrin IX elimination by body excreta: a new noninvasive cancer diagnostic method?
Topics: Animals; Cell Line, Tumor; Diagnostic Techniques and Procedures; Feces; Humans; Male; Mice; Prostati | 2013 |
Differentiation enhances aminolevulinic acid-dependent photodynamic treatment of LNCaP prostate cancer cells.
Topics: Aminolevulinic Acid; Cell Differentiation; Flow Cytometry; Humans; Male; Metribolone; Photochemother | 2002 |
Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - in vivo experiments on the dunning rat tumor model.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Male; Photochemotherapy; Prostatic Neoplasms; | 2004 |
Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells.
Topics: Aminolevulinic Acid; Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Sur | 2006 |
In vivo quantification of fluorescent molecular markers in real-time by ratio imaging for diagnostic screening and image-guided surgery.
Topics: Diagnostic Imaging; Fluorescence; Humans; Indoles; Intraoperative Period; Male; Models, Theoretical; | 2007 |
Interstitial photodynamic therapy in the canine prostate with disulfonated aluminum phthalocyanine and 5-aminolevulinic acid-induced protoporphyrin IX.
Topics: Aminolevulinic Acid; Animals; Atrophy; Collagen; Dogs; Indoles; Lasers; Light; Male; Organometallic | 1997 |
Hormonal modulation of the accumulation of 5-aminolevulinic acid-induced protoporphyrin and phototoxicity in prostate cancer cells.
Topics: Aminolevulinic Acid; Animals; Blood; Cattle; Cell Division; Cell Survival; Culture Media; Dihydrotes | 1997 |
Delta-aminolevulinic acid-mediated photosensitization of prostate cell lines: implication for photodynamic therapy of prostate cancer.
Topics: Aminolevulinic Acid; Cell Survival; Humans; Male; Microscopy, Electron; Mitochondria; Photochemother | 1998 |