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protoporphyrin ix and Osteosarcoma

protoporphyrin ix has been researched along with Osteosarcoma in 3 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)

Research Excerpts

ExcerptRelevanceReference
"We observed that two osteosarcoma cell lines from the same tumor displayed marked differences in their sensitivities to photodynamic therapy (PDT) with aminolevulinic acid hexyl ester (hALA-PDT)."7.75Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. ( Matsumura, Y; Nomura, J; Tagawa, T; Watanabe, Y; Yanase, S, 2009)
"We observed that two osteosarcoma cell lines from the same tumor displayed marked differences in their sensitivities to photodynamic therapy (PDT) with aminolevulinic acid hexyl ester (hALA-PDT)."3.75Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. ( Matsumura, Y; Nomura, J; Tagawa, T; Watanabe, Y; Yanase, S, 2009)
"In the present study, we have investigated a combination of photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) and simultaneous hyperthermia (HT) on osteosarcoma (HOSM-1) cells, squamous cell carcinoma (KB) cells and fibroblasts (HF), including an assessment of the differences in the sensitivity of these cells to such treatment in vitro."3.73Enhancement of the effect of 5-aminolevulinic acid-based photodynamic therapy by simultaneous hyperthermia. ( Kinoshita, M; Matsumura, Y; Nagai, K; Nakanishi, H; Nomura, J; Ohnishi, Y; Tagawa, T; Tokuda, T; Yanase, S, 2005)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Makhadmeh, GN1
Abdul Aziz, A1
Yanase, S2
Nomura, J2
Matsumura, Y2
Watanabe, Y1
Tagawa, T2
Nagai, K1
Kinoshita, M1
Nakanishi, H1
Ohnishi, Y1
Tokuda, T1

Other Studies

3 other studies available for protoporphyrin ix and Osteosarcoma

ArticleYear
Photodynamic application of protoporphyrin IX as a photosensitizer encapsulated by silica nanoparticles.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup3

    Topics: Bone Neoplasms; Humans; Nanoparticles; Osteosarcoma; Photochemotherapy; Photosensitizing Agents; Pro

2018
Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia.
    Photomedicine and laser surgery, 2009, Volume: 27, Issue:5

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Combined Modality Therapy; Humans; Hyperthermia, Induced; Inf

2009
Enhancement of the effect of 5-aminolevulinic acid-based photodynamic therapy by simultaneous hyperthermia.
    International journal of oncology, 2005, Volume: 27, Issue:1

    Topics: Aminolevulinic Acid; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Separation; Ch

2005