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protoporphyrin ix and Medulloblastoma

protoporphyrin ix has been researched along with Medulloblastoma in 3 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)

Research Excerpts

ExcerptRelevanceReference
" Cellular uptake and photodynamic inactivation after incubation with this photosensitizer have neither been examined in medulloblastoma cells in vitro, nor compared with 5-aminolevulinic acid-derived protoporphyrin IX (5-ALA-derived PpIX)."7.78In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012)
" Cellular uptake and photodynamic inactivation after incubation with this photosensitizer have neither been examined in medulloblastoma cells in vitro, nor compared with 5-aminolevulinic acid-derived protoporphyrin IX (5-ALA-derived PpIX)."3.78In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Briel-Pump, A1
Beez, T1
Ebbert, L1
Remke, M1
Weinhold, S1
Sabel, MC1
Sorg, RV1
Morfouace, M1
Cheepala, S1
Jackson, S1
Fukuda, Y1
Patel, YT1
Fatima, S1
Kawauchi, D1
Shelat, AA1
Stewart, CF1
Sorrentino, BP1
Schuetz, JD1
Roussel, MF1
Ritz, R1
Scheidle, C1
Noell, S1
Roser, F1
Schenk, M1
Dietz, K1
Strauss, WS1

Other Studies

3 other studies available for protoporphyrin ix and Medulloblastoma

ArticleYear
Accumulation of protoporphyrin IX in medulloblastoma cell lines and sensitivity to subsequent photodynamic treatment.
    Journal of photochemistry and photobiology. B, Biology, 2018, Volume: 189

    Topics: Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Ferr

2018
ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy.
    Cancer research, 2015, Sep-15, Volume: 75, Issue:18

    Topics: Adenine; Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily G, M

2015
In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Aminolevulinic Acid; Anthracenes; Cell Line, Tumor; Cerebellar Neoplasms; Humans; Medulloblastoma; M

2012