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protoporphyrin ix and Margins of Excision

protoporphyrin ix has been researched along with Margins of Excision in 4 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Margins of Excision: The edges of tissue removed in a surgery for assessment of the effectiveness of a surgical procedure in achieving the local control of a neoplasm and the adequacy of tumor removal. When the margin is negative or not involved by tumor (e.g., CANCER) it suggests all of the tumor has been removed by the surgery.

Research Excerpts

ExcerptRelevanceReference
"FLIm measurements of resection margins presented a range of PpIX and NAD(P)H lifetime values (τPpIX       ∼  3 to 14 ns, τNAD(P)H  =  3 to 6 ns) associated with unaffected tissue and areas of low-density tumor infiltration."1.72First in patient assessment of brain tumor infiltrative margins using simultaneous time-resolved measurements of 5-ALA-induced PpIX fluorescence and tissue autofluorescence. ( Alfonso-García, A; Anbunesan, SN; Bec, J; Bloch, O; Fereidouni, F; Jin, LW; Lee, HS; Marcu, L; Zhou, X, 2022)
"Gliomas are infiltrative brain tumors with a margin difficult to identify."1.56Machine learning-based prediction of glioma margin from 5-ALA induced PpIX fluorescence spectroscopy. ( Alston, L; Brevet, PF; Frindel, C; Guyotat, J; Leclerc, P; Mahieu-Williame, L; Meyronet, D; Montcel, B; Ray, C; Rousseau, D, 2020)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Alfonso-García, A1
Zhou, X1
Bec, J1
Anbunesan, SN1
Fereidouni, F1
Jin, LW1
Lee, HS1
Bloch, O1
Marcu, L1
Leclerc, P1
Ray, C1
Mahieu-Williame, L1
Alston, L1
Frindel, C1
Brevet, PF1
Meyronet, D1
Guyotat, J1
Montcel, B1
Rousseau, D1
Suero Molina, E1
Stögbauer, L1
Jeibmann, A1
Warneke, N1
Stummer, W1
Yagi, R1
Kawabata, S1
Ikeda, N1
Nonoguchi, N1
Furuse, M1
Katayama, Y1
Kajimoto, Y1
Kuroiwa, T1

Other Studies

4 other studies available for protoporphyrin ix and Margins of Excision

ArticleYear
First in patient assessment of brain tumor infiltrative margins using simultaneous time-resolved measurements of 5-ALA-induced PpIX fluorescence and tissue autofluorescence.
    Journal of biomedical optics, 2022, Volume: 27, Issue:2

    Topics: Aminolevulinic Acid; Brain Neoplasms; Fluorescence; Humans; Margins of Excision; Photosensitizing Ag

2022
Machine learning-based prediction of glioma margin from 5-ALA induced PpIX fluorescence spectroscopy.
    Scientific reports, 2020, 01-29, Volume: 10, Issue:1

    Topics: Aminolevulinic Acid; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cluster Analysis; Compute

2020
Validating a new generation filter system for visualizing 5-ALA-induced PpIX fluorescence in malignant glioma surgery: a proof of principle study.
    Acta neurochirurgica, 2020, Volume: 162, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Brain Neoplasms; Cell Count; Female; Fl

2020
Intraoperative 5-aminolevulinic acid-induced photodynamic diagnosis of metastatic brain tumors with histopathological analysis.
    World journal of surgical oncology, 2017, Sep-29, Volume: 15, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Brain; Brain Neoplasms; Female; Fluorescence; Humans; Intraoperati

2017