protoporphyrin ix has been researched along with Macular Degeneration in 2 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Macular Degeneration: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Photosensitization of choriocapillary endothelium with blood-borne photosensitizers, such as protoporphyrin IX, has been proposed as a mechanism for the choriocapillary sclerosis and Bruch's membrane deposits seen in age-related macular degeneration." | 3.68 | Light-induced deposits in Bruch's membrane of protoporphyric mice. ( Bynoe, LA; Gottsch, JD; Green, WR; Harlan, JB; Rencs, EV, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gottsch, JD | 2 |
| Bynoe, LA | 2 |
| Harlan, JB | 1 |
| Rencs, EV | 1 |
| Green, WR | 1 |
| Pou, S | 1 |
| Rosen, GM | 1 |
2 other studies available for protoporphyrin ix and Macular Degeneration
| Article | Year |
|---|---|
Light-induced deposits in Bruch's membrane of protoporphyric mice.
Topics: Animals; Bruch Membrane; Capillaries; Choroid; Disease Models, Animal; Extracellular Matrix; Griseof | 1993 |
Hematogenous photosensitization. A mechanism for the development of age-related macular degeneration.
Topics: Aging; Anthracenes; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Light; Macular Degenerati | 1990 |