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protoporphyrin ix and Macular Degeneration

protoporphyrin ix has been researched along with Macular Degeneration in 2 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Macular Degeneration: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Research Excerpts

ExcerptRelevanceReference
"Photosensitization of choriocapillary endothelium with blood-borne photosensitizers, such as protoporphyrin IX, has been proposed as a mechanism for the choriocapillary sclerosis and Bruch's membrane deposits seen in age-related macular degeneration."3.68Light-induced deposits in Bruch's membrane of protoporphyric mice. ( Bynoe, LA; Gottsch, JD; Green, WR; Harlan, JB; Rencs, EV, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gottsch, JD2
Bynoe, LA2
Harlan, JB1
Rencs, EV1
Green, WR1
Pou, S1
Rosen, GM1

Other Studies

2 other studies available for protoporphyrin ix and Macular Degeneration

ArticleYear
Light-induced deposits in Bruch's membrane of protoporphyric mice.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1993, Volume: 111, Issue:1

    Topics: Animals; Bruch Membrane; Capillaries; Choroid; Disease Models, Animal; Extracellular Matrix; Griseof

1993
Hematogenous photosensitization. A mechanism for the development of age-related macular degeneration.
    Investigative ophthalmology & visual science, 1990, Volume: 31, Issue:9

    Topics: Aging; Anthracenes; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Light; Macular Degenerati

1990