protoporphyrin ix has been researched along with Leucocythaemia in 11 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human adenocarcinoma cells of the line WiDr and human leukemia T cells of the line Jurkat were incubated with 5-aminolevulinic acid and found to produce protoporphyrin IX (PpIX)." | 3.71 | Transfer of protoporphyrin IX between cells. ( Ma, LW; Moan, J; Stokke, T, 2002) |
| "To verify if photodynamic therapy (PDT) could overcome multidrug resistance (MDR) when it it applied to eradicate minimal residual disease in patients with leukemia, we investigated the fluorescence kinetics of 5-aminolaevulinic acid (ALA)-induced protoporphyrin IX (PpIX) and the effect of subsequent photodynamic therapy on MDR leukemia cells, which express P-glycoprotein (P-gp), as well as on their parent cells." | 3.71 | 5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells. ( Hashimoto, K; Li, W; Ohnishi, K; Ohno, R; Yamada, I; Zhang, WJ, 2001) |
| " Erythroid differentiation of human leukemia cell line K562 is induced by hemin or protoporphyrin IX in the presence of fetal bovine serum (FBS)." | 3.69 | Possible involvement of retinoid-like cofactor in serum in hemin/protoporphyrin-IX-induced differentiation of human leukemia K562 cells. ( Hashimoto, Y; Iwasaki, S; Kagechika, H; Nakajima, O; Shudo, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Su, X | 1 |
| Wang, X | 1 |
| Leung, AW | 1 |
| Xu, C | 1 |
| Wang, P | 1 |
| Liu, Q | 1 |
| Diez, B | 1 |
| Cordo Russo, R | 1 |
| Teijo, MJ | 1 |
| Hajos, S | 1 |
| Batlle, A | 1 |
| Fukuda, H | 1 |
| Moan, J | 1 |
| Ma, LW | 1 |
| Stokke, T | 1 |
| Louache, F | 2 |
| Testa, U | 2 |
| Pelicci, P | 1 |
| Thomopoulos, P | 2 |
| Titeux, M | 2 |
| Rochant, H | 2 |
| Nakajima, O | 1 |
| Kagechika, H | 1 |
| Shudo, K | 1 |
| Hashimoto, Y | 1 |
| Iwasaki, S | 1 |
| Grebenová, D | 1 |
| Cajthamlová, H | 2 |
| Bartosová, J | 2 |
| Marinov, J | 1 |
| Klamová, H | 1 |
| Fuchs, O | 1 |
| Hrkal, Z | 3 |
| Belicková, M | 1 |
| Bruchová, H | 1 |
| Brdicka, R | 1 |
| Rebeiz, N | 1 |
| Arkins, S | 1 |
| Kelley, KW | 1 |
| Durack, G | 1 |
| Rebeiz, CA | 1 |
| Li, W | 1 |
| Zhang, WJ | 1 |
| Ohnishi, K | 1 |
| Yamada, I | 1 |
| Ohno, R | 1 |
| Hashimoto, K | 1 |
11 other studies available for protoporphyrin ix and Leucocythaemia
| Article | Year |
|---|---|
Cytotoxic effect of protoporphyrin IX to human Leukemia U937 cells under ultrasonic irradiation.
Topics: Acetylcysteine; Apoptosis; DNA; DNA Fragmentation; Humans; Leukemia; Membrane Potential, Mitochondri | 2014 |
Ros production by endogenously generated Protoporphyrin IX in murine leukemia cells.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Line, Tumor; Drug Resistance, Neoplasm; Leukemia; Memb | 2009 |
Transfer of protoporphyrin IX between cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Communication; Cell Line, Tumor; Colonic Neoplasms; Humans | 2002 |
Regulation of transferrin receptors in human hematopoietic cell lines.
Topics: Antibodies, Monoclonal; Apoproteins; Cell Division; Cell Line; Heme; Humans; In Vitro Techniques; Ir | 1984 |
[Modulation of the expression of transferrin receptors by iron, hemin and protoporphyrin IX].
Topics: Animals; Cell Line; Cells, Cultured; Heme; Hemin; Humans; Iron; Leukemia; Porphyrins; Protoporphyrin | 1983 |
Possible involvement of retinoid-like cofactor in serum in hemin/protoporphyrin-IX-induced differentiation of human leukemia K562 cells.
Topics: Cell Differentiation; Charcoal; Culture Media; Erythrocytes; Gene Expression; Genes, myc; Hemin; Hum | 1995 |
Selective destruction of leukaemic cells by photo-activation of 5-aminolaevulinic acid-induced protoporphyrin-IX.
Topics: Aminolevulinic Acid; Bone Marrow Cells; Cell Division; Cell Survival; Hematopoietic Stem Cells; HL-6 | 1998 |
Genes involved in the destruction of leukaemic cells by induced photosensitivity.
Topics: Aminolevulinic Acid; Apoptosis; Cell Survival; DNA, Complementary; Gene Expression Profiling; Gene E | 2000 |
Accumulation of protoporphyrin-IX (PpIX) in leukemic cell lines following induction by 5-aminolevulinic acid (ALA).
Topics: Aminolevulinic Acid; Animals; Cattle; Culture Media; Ferrochelatase; HL-60 Cells; Humans; Jurkat Cel | 2000 |
Modulator of heme biosynthesis induces apoptosis in leukemia cells.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Cycle; Cell Division; Cell Membrane Permeability; Cell | 2001 |
5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells.
Topics: Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dermatitis, | 2001 |