protoporphyrin ix has been researched along with Keratosis in 7 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Keratosis: Any horny growth such as a wart or callus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare pain during PDT using two different fluence rates, and also to evaluate the association between pain and protoporphyrin IX (PpIX) fluorescence, lesion type, lesion preparation and lesion localization." | 7.74 | Pain during photodynamic therapy is associated with protoporphyrin IX fluorescence and fluence rate. ( Philipsen, PA; Skiveren, J; Wiegell, SR; Wulf, HC, 2008) |
| "To compare pain during PDT using two different fluence rates, and also to evaluate the association between pain and protoporphyrin IX (PpIX) fluorescence, lesion type, lesion preparation and lesion localization." | 3.74 | Pain during photodynamic therapy is associated with protoporphyrin IX fluorescence and fluence rate. ( Philipsen, PA; Skiveren, J; Wiegell, SR; Wulf, HC, 2008) |
| " The studies investigated the influence of patch application duration on PPIX-specific fluorescence and the pharmacokinetic properties of the 5-ALA patch." | 1.35 | Fluorescence characteristics and pharmacokinetic properties of a novel self-adhesive 5-ALA patch for photodynamic therapy of actinic keratoses. ( Ackermann, G; Birkel, M; Breuer, M; Ebeling, A; Fauteck, JD; Moor, AC; Ortland, C, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerritsen, MJ | 2 |
| Smits, T | 2 |
| Kleinpenning, MM | 1 |
| van de Kerkhof, PC | 2 |
| van Erp, PE | 2 |
| Robles, CA | 1 |
| Fauteck, JD | 1 |
| Ackermann, G | 1 |
| Birkel, M | 1 |
| Breuer, M | 1 |
| Moor, AC | 1 |
| Ebeling, A | 1 |
| Ortland, C | 1 |
| Wiegell, SR | 2 |
| Skiveren, J | 1 |
| Philipsen, PA | 2 |
| Wulf, HC | 2 |
| Haedersdal, M | 1 |
| Eriksen, P | 1 |
| Enk, CD | 1 |
| Krammer, B | 1 |
| Plaetzer, K | 1 |
| Kennedy, JC | 1 |
| Pottier, RH | 1 |
| Pross, DC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Half-side Comparative Trial of Fractional Laser-assisted Daylight Photodynamic Therapy Versus Daylight Photodynamic Therapy in Organ Transplant Recipients With Multiple Actinic Keratoses of the Scalp or Forehead[NCT01898936] | 12 participants (Actual) | Interventional | 2013-08-31 | Completed | |||
| Photodynamic Therapy for Treatment of Cutaneous Squamous Cell Carcinoma in Situ[NCT03025724] | 40 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for protoporphyrin ix and Keratosis
| Article | Year |
|---|---|
Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy.
Topics: Aminolevulinic Acid; Animals; Humans; Keratosis; Photochemotherapy; Photosensitizing Agents; Protopo | 2009 |
ALA and its clinical impact, from bench to bedside.
Topics: Aminolevulinic Acid; Dendritic Cells; Fluorescence; Humans; Keratosis; Lymphocytes; Macrophages; Neo | 2008 |
2 trials available for protoporphyrin ix and Keratosis
| Article | Year |
|---|---|
Continuous activation of PpIX by daylight is as effective as and less painful than conventional photodynamic therapy for actinic keratoses; a randomized, controlled, single-blinded study.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Dose-Response Relationship, Drug; Facial Dermatoses; F | 2008 |
Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Keratosis; Ph | 1990 |
3 other studies available for protoporphyrin ix and Keratosis
| Article | Year |
|---|---|
Correlation between macroscopic fluorescence and protoporphyrin IX content in psoriasis and actinic keratosis following application of aminolevulinic acid.
Topics: Aminolevulinic Acid; DNA; Humans; Keratosis; Protoporphyrins; Psoriasis; Spectrometry, Fluorescence | 2005 |
Fluorescence characteristics and pharmacokinetic properties of a novel self-adhesive 5-ALA patch for photodynamic therapy of actinic keratoses.
Topics: Adhesives; Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Case-Control Stu | 2008 |
Pain during photodynamic therapy is associated with protoporphyrin IX fluorescence and fluence rate.
Topics: Acne Vulgaris; Adult; Aged; Female; Humans; Keratosis; Male; Pain; Pain Measurement; Photochemothera | 2008 |