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protoporphyrin ix and Keloid

protoporphyrin ix has been researched along with Keloid in 2 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.

Research Excerpts

ExcerptRelevanceReference
"In this study, we evaluated the in vitro cytotoxic effect of PDT at 5J/cm(2) and 10J/cm(2) of red light (633 ± 3nm) using 5-aminolevulinic acid (ALA) and methyl aminolevulinate (MAL) with and without DW, on keloid fibroblasts compared to normal skin fibroblasts."3.77Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy. ( Allan, D; Allan, E; Bayat, A; Colthurst, J; Sebastian, A, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sebastian, A2
Allan, E2
Allan, D2
Colthurst, J1
Bayat, A2
Mendoza, J1
Mandal, P1
Alonso-Rasgado, T1

Other Studies

2 other studies available for protoporphyrin ix and Keloid

ArticleYear
Addition of novel degenerate electrical waveform stimulation with photodynamic therapy significantly enhances its cytotoxic effect in keloid fibroblasts: first report of a potential combination therapy.
    Journal of dermatological science, 2011, Volume: 64, Issue:3

    Topics: Adult; Aged; Aminolevulinic Acid; Apoptosis; Blotting, Western; Case-Control Studies; Caspase 3; Cel

2011
Differential cytotoxic response in keloid fibroblasts exposed to photodynamic therapy is dependent on photosensitiser precursor, fluence and location of fibroblasts within the lesion.
    Archives of dermatological research, 2012, Volume: 304, Issue:7

    Topics: Adult; Aminolevulinic Acid; Apoptosis; Cell Differentiation; Cells, Cultured; Cellular Senescence; F

2012