protoporphyrin ix has been researched along with Friedreich Disease in 4 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Excerpt | Relevance | Reference |
---|---|---|
"The authors carried out a 1-year, randomized, placebo-controlled trial of idebenone in 29 patients with Friedreich ataxia." | 5.10 | Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial. ( Di Donato, S; Fiorentini, C; Marano, L; Mariotti, C; Solari, A; Torta, D, 2003) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (75.00) | 29.6817 |
2010's | 1 (25.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Steinkellner, H | 1 |
Singh, HN | 1 |
Muckenthaler, MU | 1 |
Goldenberg, H | 1 |
Moganty, RR | 1 |
Scheiber-Mojdehkar, B | 1 |
Sturm, B | 1 |
Mariotti, C | 1 |
Solari, A | 1 |
Torta, D | 1 |
Marano, L | 1 |
Fiorentini, C | 1 |
Di Donato, S | 1 |
Buyse, G | 1 |
Mertens, L | 1 |
Di Salvo, G | 1 |
Matthijs, I | 1 |
Weidemann, F | 1 |
Eyskens, B | 1 |
Goossens, W | 1 |
Goemans, N | 1 |
Sutherland, GR | 1 |
Van Hove, JL | 1 |
Becker, EM | 1 |
Greer, JM | 1 |
Ponka, P | 1 |
Richardson, DR | 1 |
2 trials available for protoporphyrin ix and Friedreich Disease
Article | Year |
---|---|
Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial.
Topics: Adolescent; Adult; Benzoquinones; Cardiomyopathy, Hypertrophic; Child; Erythrocytes; Female; Frataxi | 2003 |
Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring.
Topics: Adolescent; Adult; Benzoquinones; Cardiomyopathy, Hypertrophic; Child; Erythrocytes; Female; Frataxi | 2003 |
2 other studies available for protoporphyrin ix and Friedreich Disease
Article | Year |
---|---|
No changes in heme synthesis in human Friedreich´s ataxia erythroid progenitor cells.
Topics: Case-Control Studies; Cells, Cultured; Erythroid Precursor Cells; Erythropoiesis; Ferrochelatase; Fr | 2017 |
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization.
Topics: Animals; Cation Transport Proteins; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Down-Regula | 2002 |