Page last updated: 2024-11-03

protoporphyrin ix and Friedreich Disease

protoporphyrin ix has been researched along with Friedreich Disease in 4 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Research Excerpts

ExcerptRelevanceReference
"The authors carried out a 1-year, randomized, placebo-controlled trial of idebenone in 29 patients with Friedreich ataxia."5.10Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial. ( Di Donato, S; Fiorentini, C; Marano, L; Mariotti, C; Solari, A; Torta, D, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Steinkellner, H1
Singh, HN1
Muckenthaler, MU1
Goldenberg, H1
Moganty, RR1
Scheiber-Mojdehkar, B1
Sturm, B1
Mariotti, C1
Solari, A1
Torta, D1
Marano, L1
Fiorentini, C1
Di Donato, S1
Buyse, G1
Mertens, L1
Di Salvo, G1
Matthijs, I1
Weidemann, F1
Eyskens, B1
Goossens, W1
Goemans, N1
Sutherland, GR1
Van Hove, JL1
Becker, EM1
Greer, JM1
Ponka, P1
Richardson, DR1

Trials

2 trials available for protoporphyrin ix and Friedreich Disease

ArticleYear
Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial.
    Neurology, 2003, May-27, Volume: 60, Issue:10

    Topics: Adolescent; Adult; Benzoquinones; Cardiomyopathy, Hypertrophic; Child; Erythrocytes; Female; Frataxi

2003
Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring.
    Neurology, 2003, May-27, Volume: 60, Issue:10

    Topics: Adolescent; Adult; Benzoquinones; Cardiomyopathy, Hypertrophic; Child; Erythrocytes; Female; Frataxi

2003

Other Studies

2 other studies available for protoporphyrin ix and Friedreich Disease

ArticleYear
No changes in heme synthesis in human Friedreich´s ataxia erythroid progenitor cells.
    Gene, 2017, Jul-20, Volume: 621

    Topics: Case-Control Studies; Cells, Cultured; Erythroid Precursor Cells; Erythropoiesis; Ferrochelatase; Fr

2017
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization.
    Blood, 2002, May-15, Volume: 99, Issue:10

    Topics: Animals; Cation Transport Proteins; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Down-Regula

2002