protoporphyrin ix has been researched along with Friedreich Disease in 4 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors carried out a 1-year, randomized, placebo-controlled trial of idebenone in 29 patients with Friedreich ataxia." | 5.10 | Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial. ( Di Donato, S; Fiorentini, C; Marano, L; Mariotti, C; Solari, A; Torta, D, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steinkellner, H | 1 |
| Singh, HN | 1 |
| Muckenthaler, MU | 1 |
| Goldenberg, H | 1 |
| Moganty, RR | 1 |
| Scheiber-Mojdehkar, B | 1 |
| Sturm, B | 1 |
| Mariotti, C | 1 |
| Solari, A | 1 |
| Torta, D | 1 |
| Marano, L | 1 |
| Fiorentini, C | 1 |
| Di Donato, S | 1 |
| Buyse, G | 1 |
| Mertens, L | 1 |
| Di Salvo, G | 1 |
| Matthijs, I | 1 |
| Weidemann, F | 1 |
| Eyskens, B | 1 |
| Goossens, W | 1 |
| Goemans, N | 1 |
| Sutherland, GR | 1 |
| Van Hove, JL | 1 |
| Becker, EM | 1 |
| Greer, JM | 1 |
| Ponka, P | 1 |
| Richardson, DR | 1 |
2 trials available for protoporphyrin ix and Friedreich Disease
| Article | Year |
|---|---|
Idebenone treatment in Friedreich patients: one-year-long randomized placebo-controlled trial.
Topics: Adolescent; Adult; Benzoquinones; Cardiomyopathy, Hypertrophic; Child; Erythrocytes; Female; Frataxi | 2003 |
Idebenone treatment in Friedreich's ataxia: neurological, cardiac, and biochemical monitoring.
Topics: Adolescent; Adult; Benzoquinones; Cardiomyopathy, Hypertrophic; Child; Erythrocytes; Female; Frataxi | 2003 |
2 other studies available for protoporphyrin ix and Friedreich Disease
| Article | Year |
|---|---|
No changes in heme synthesis in human Friedreich´s ataxia erythroid progenitor cells.
Topics: Case-Control Studies; Cells, Cultured; Erythroid Precursor Cells; Erythropoiesis; Ferrochelatase; Fr | 2017 |
Erythroid differentiation and protoporphyrin IX down-regulate frataxin expression in Friend cells: characterization of frataxin expression compared to molecules involved in iron metabolism and hemoglobinization.
Topics: Animals; Cation Transport Proteins; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Down-Regula | 2002 |