Page last updated: 2024-11-03

protoporphyrin ix and Esophageal Neoplasms

protoporphyrin ix has been researched along with Esophageal Neoplasms in 15 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Esophageal Neoplasms: Tumors or cancer of the ESOPHAGUS.

Research Excerpts

ExcerptRelevanceReference
"Four patients with known gastric adenoma (n = 1), macroscopically undetected but histologically proven esophageal squamous cell cancer (n = 1), suspected early cancer of the esophagus (n = 1), and multiple duodenal adenomas (n = 1) were sensitized with 5-aminolevulinic acid administered orally (15 mg/kg body weight)."3.70Endoscopic photodynamic diagnosis: oral aminolevulinic acid is a marker of GI cancer and dysplastic lesions. ( Hahn, EG; Hochberger, J; Mayinger, B; Reh, H, 1999)
"Preliminary studies in early esophageal cancer also show effectiveness."2.41Photodynamic therapy for esophageal cancer. Update. ( Greenwald, BD, 2000)
"Barrett's esophagus is strongly associated with adenocarcinoma."1.32Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid. ( Dorta, G; Felley, C; Fontolliet, C; Gabrecht, T; Grosjean, P; Jornod, P; Lange, N; Monnier, P; Stepinac, T; van den Bergh, H; vanMelle, G; Wagnières, G, 2003)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (33.33)18.2507
2000's8 (53.33)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yeh, SC1
Sahli, S1
Andrews, DW1
Patterson, MS1
Armstrong, D1
Provias, J1
Fang, Q1
Chen, X1
Zhao, P1
Chen, F1
Li, L1
Luo, R1
Brand, S1
Wang, TD1
Schomacker, KT1
Poneros, JM1
Lauwers, GY1
Compton, CC1
Pedrosa, MC1
Nishioka, NS1
Ortner, MA1
Ebert, B1
Hein, E1
Zumbusch, K1
Nolte, D1
Sukowski, U1
Weber-Eibel, J1
Fleige, B1
Dietel, M1
Stolte, M1
Oberhuber, G1
Porschen, R1
Klump, B1
Hörtnagl, H1
Lochs, H2
Rinneberg, H1
Stepinac, T1
Felley, C1
Jornod, P1
Lange, N1
Gabrecht, T1
Fontolliet, C1
Grosjean, P1
vanMelle, G1
van den Bergh, H1
Monnier, P1
Wagnières, G1
Dorta, G1
Ji, Z1
Yang, G1
Vasovic, V1
Cunderlikova, B1
Suo, Z1
Nesland, JM1
Peng, Q1
Ortner, M1
Messmann, H2
Knüchel, R1
Endlicher, E1
Hauser, T1
Szeimies, RM1
Kullmann, F1
Bäumler, W1
Schölmerich, J1
Mĺkvy, P1
Regula, J1
Conio, M1
Pauer, M1
Millson, CE1
MacRobert, AJ1
Bown, SG1
Hinnen, P2
de Rooij, FW2
van Velthuysen, ML1
Edixhoven, A2
van Hillegersberg, R2
Tilanus, HW2
Wilson, JH2
Siersema, PD2
Mayinger, B2
Reh, H2
Hochberger, J1
Hahn, EG2
Terlouw, EM1
van Dekken, H1
Greenwald, BD1
Neidhardt, S1
Martus, P1
Pech, O1
Nagy, CD1
Gossner, L1
May, A1
Ell, C1

Reviews

1 review available for protoporphyrin ix and Esophageal Neoplasms

ArticleYear
Photodynamic therapy for esophageal cancer. Update.
    Chest surgery clinics of North America, 2000, Volume: 10, Issue:3

    Topics: Animals; Barrett Esophagus; Dihematoporphyrin Ether; Esophageal Neoplasms; Humans; Photochemotherapy

2000

Trials

1 trial available for protoporphyrin ix and Esophageal Neoplasms

ArticleYear
Photodynamic therapy for gastrointestinal tumors using three photosensitizers--ALA induced PPIX, Photofrin and MTHPC. A pilot study.
    Neoplasma, 1998, Volume: 45, Issue:3

    Topics: Adult; Aged; Aminolevulinic Acid; Dihematoporphyrin Ether; Duodenal Neoplasms; Esophageal Neoplasms;

1998

Other Studies

13 other studies available for protoporphyrin ix and Esophageal Neoplasms

ArticleYear
5-Aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett's esophagus cellular models.
    Journal of biomedical optics, 2015, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Algorithms; Aminolevulinic Acid; Barrett Esophagus; Biomarkers; Esophageal Neoplasms

2015
Effect and mechanism of 5-aminolevulinic acid-mediated photodynamic therapy in esophageal cancer.
    Lasers in medical science, 2011, Volume: 26, Issue:1

    Topics: Aminolevulinic Acid; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Prolifer

2011
Detection of high-grade dysplasia in Barrett's esophagus by spectroscopy measurement of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
    Gastrointestinal endoscopy, 2002, Volume: 56, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esopha

2002
Time gated fluorescence spectroscopy in Barrett's oesophagus.
    Gut, 2003, Volume: 52, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Biomarkers,

2003
Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid.
    Endoscopy, 2003, Volume: 35, Issue:8

    Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Carcinoma in Situ; Esopha

2003
Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines.
    Journal of photochemistry and photobiology. B, Biology, 2006, Sep-01, Volume: 84, Issue:3

    Topics: Adenosine Triphosphate; Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor;

2006
[Eradication of high-grade dysplasia in Barrett esophagus by photodynamic therapy with endogenously generated protoporphyrin IX].
    Zeitschrift fur Gastroenterologie, 1998, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Fe

1998
[Photodynamic diagnosis of gastrointestinal precancerous lesions after sensitization with 5-aminolevulinic acid. A pilot study].
    Deutsche medizinische Wochenschrift (1946), 1998, Apr-24, Volume: 123, Issue:17

    Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colorectal Neopla

1998
Biochemical basis of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation: a study in patients with (pre)malignant lesions of the oesophagus.
    British journal of cancer, 1998, Volume: 78, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Female; Ferroc

1998
Endoscopic photodynamic diagnosis: oral aminolevulinic acid is a marker of GI cancer and dysplastic lesions.
    Gastrointestinal endoscopy, 1999, Volume: 50, Issue:2

    Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Duodenal Neoplasms; Endoscopy, Digesti

1999
Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid.
    British journal of cancer, 2000, Volume: 83, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett E

2000
Fluorescence induced with 5-aminolevulinic acid for the endoscopic detection and follow-up of esophageal lesions.
    Gastrointestinal endoscopy, 2001, Volume: 54, Issue:5

    Topics: Administration, Oral; Aged; Aminolevulinic Acid; Biopsy; Esophageal Neoplasms; Esophagoscopy; Female

2001
Photodynamic therapy of human Barrett's cancer using 5-aminolaevulinic acid-induced protoporphyrin IX: an in-vivo dosimetry study in athymic nude mice.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:6

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Barrett Esophagus; Esophageal Neoplasms; Humans; Mice;

2002