protoporphyrin ix has been researched along with Disease Models, Animal in 48 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "7h) PDT treatment in a nude mouse model of human glioblastoma by using organic light emitting diode (OLED) with single dose of 5-aminolevulinic acid (ALA) administration as photosensitizer." | 3.81 | Low-fluence rate, long duration photodynamic therapy in glioma mouse model using organic light emitting diode (OLED). ( Chen, PH; Chiou, SH; Dong, CY; Guo, HW; Ho, MH; Hsieh, YS; Huang, WT; Lee, YJ; Lin, LT; Wang, HW, 2015) |
| "Photosensitization of choriocapillary endothelium with blood-borne photosensitizers, such as protoporphyrin IX, has been proposed as a mechanism for the choriocapillary sclerosis and Bruch's membrane deposits seen in age-related macular degeneration." | 3.68 | Light-induced deposits in Bruch's membrane of protoporphyric mice. ( Bynoe, LA; Gottsch, JD; Green, WR; Harlan, JB; Rencs, EV, 1993) |
| " Moreover, this therapeutic combination of agents is safe and does not weaken the healing of the sutured enterotomy site." | 1.62 | Prevention of adhesions post-abdominal surgery: Assessing the safety and efficacy of Chitogel with Deferiprone in a rat model. ( Bassiouni, A; Bennett, C; Cooksley, C; Finnie, J; Jones, CF; Maddern, G; Moratti, S; Psaltis, AJ; Quarrington, RD; Trochsler, M; Vediappan, RS; Vreugde, S; Wormald, PJ, 2021) |
| "ZJ01 treatment reduced hyperoxia-induced inflammation and increased the activation of Nrf2 and HO-1 compared with the vehicle-treated mice." | 1.56 | ZJ01, a Small Molecule Inhibitor of the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction, Reduces Hyperoxic Acute Lung Injury in a Mouse Model. ( Du, S; Huang, X; Li, Q; Lin, S; Wan, J; Zeng, L, 2020) |
| "tuberculosis (TB)." | 1.51 | Results of a pilot study of isoniazid in patients with erythropoietic protoporphyria. ( Anderson, KE; Balwani, M; Bissel, MD; Bloomer, JR; Desnick, RJ; Gouya, L; Parker, CJ; Phillips, JD; Puy, H; Singal, A, 2019) |
| " Herein, we performed animal and human studies to investigate whether 5-ALA dosed glioma cells, in vitro and in vivo, release PpIX positive EVs in circulation which can be captured and analyzed." | 1.51 | Characterization of plasma-derived protoporphyrin-IX-positive extracellular vesicles following 5-ALA use in patients with malignant glioma. ( Ayinon, C; Balaj, L; Carter, BS; Charest, A; Delcuze, B; Ghiran, I; Hochberg, FH; Jones, PS; Lansbury, E; Mordecai, S; Small, JL; Tigges, J; Yekula, A, 2019) |
| "Compared to the mice without treatment, neointimal hyperplasia was reduced in the mice that received GBE treatment for 28 days in a dose-dependent manner." | 1.51 | Activation of heme oxygenase-1 by Ginkgo biloba extract differentially modulates endothelial and smooth muscle-like progenitor cells for vascular repair. ( Chen, JS; Chen, JW; Huang, PH; Lin, FY; Lin, LY; Lin, SJ; Wang, CH; Wu, TC, 2019) |
| "Here, we report that breast cancer nodules in mice can be effectively treated by preconditioning the tumors with 1α, 25-dihydroxyvitamin D3 (calcitriol; Vit D) prior to administering 5-aminolevulinate (ALA)-based PDT." | 1.42 | Vitamin D enhances the efficacy of photodynamic therapy in a murine model of breast cancer. ( Anand, S; Maytin, EV; Rollakanti, KR, 2015) |
| "Oxidative liver injury during steatohepatitis results in aggregation and transglutaminase-2 (TG2)-mediated crosslinking of the keratin cytoplasmic intermediate filament proteins (IFs) to form Mallory-Denk body (MDB) inclusions." | 1.39 | Lamin aggregation is an early sensor of porphyria-induced liver injury. ( Ernst, SA; Griggs, NW; Herrmann, H; Kwan, R; Maitra, D; Omary, MB; Singla, A; Snider, NT, 2013) |
| "Rat adjuvant arthritis is an experimental model widely used to evaluate etiopathogenetic mechanisms in chronic inflammation." | 1.33 | Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis. ( Alcaraz, MJ; Cerdá, JM; Devesa, I; Ferrándiz, ML; Guillén, I, 2005) |
| "Rats bearing orthotopic bladder tumors were treated either intravesically or intravenously with graded doses of 5-aminolevulinic acid (ALA) or PII." | 1.30 | Biodistribution of Photofrin II and 5-aminolevulinic acid-induced protoporphyrin IX in normal rat bladder and bladder tumor models: implications for photodynamic therapy. ( Brown, KM; Lown, JW; McCallum, TJ; Miller, GG; Moore, RB; Tulip, J; Xiao, Z, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (14.58) | 18.2507 |
| 2000's | 14 (29.17) | 29.6817 |
| 2010's | 23 (47.92) | 24.3611 |
| 2020's | 4 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 2 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Parker, CJ | 1 |
| Desnick, RJ | 1 |
| Bissel, MD | 1 |
| Bloomer, JR | 1 |
| Singal, A | 1 |
| Gouya, L | 2 |
| Puy, H | 2 |
| Anderson, KE | 1 |
| Balwani, M | 1 |
| Phillips, JD | 1 |
| Jones, PS | 1 |
| Yekula, A | 1 |
| Lansbury, E | 1 |
| Small, JL | 1 |
| Ayinon, C | 1 |
| Mordecai, S | 1 |
| Hochberg, FH | 1 |
| Tigges, J | 1 |
| Delcuze, B | 1 |
| Charest, A | 1 |
| Ghiran, I | 1 |
| Balaj, L | 1 |
| Carter, BS | 1 |
| Wu, TC | 1 |
| Chen, JS | 1 |
| Wang, CH | 1 |
| Huang, PH | 1 |
| Lin, FY | 1 |
| Lin, LY | 1 |
| Lin, SJ | 1 |
| Chen, JW | 1 |
| Bilmin, K | 1 |
| Kujawska, T | 1 |
| Grieb, P | 1 |
| Wan, J | 1 |
| Lin, S | 1 |
| Huang, X | 1 |
| Li, Q | 1 |
| Zeng, L | 1 |
| Du, S | 1 |
| Vediappan, RS | 1 |
| Bennett, C | 1 |
| Cooksley, C | 1 |
| Finnie, J | 1 |
| Trochsler, M | 1 |
| Quarrington, RD | 1 |
| Jones, CF | 1 |
| Bassiouni, A | 1 |
| Moratti, S | 1 |
| Psaltis, AJ | 1 |
| Maddern, G | 1 |
| Vreugde, S | 1 |
| Wormald, PJ | 1 |
| Sasaki, M | 1 |
| Tanaka, M | 1 |
| Ichikawa, H | 1 |
| Suzuki, T | 1 |
| Nishie, H | 1 |
| Ozeki, K | 1 |
| Shimura, T | 1 |
| Kubota, E | 1 |
| Tanida, S | 1 |
| Kataoka, H | 1 |
| Anand, S | 2 |
| Rollakanti, KR | 2 |
| Brankov, N | 1 |
| Brash, DE | 1 |
| Hasan, T | 3 |
| Maytin, EV | 2 |
| Singla, A | 1 |
| Griggs, NW | 1 |
| Kwan, R | 1 |
| Snider, NT | 1 |
| Maitra, D | 2 |
| Ernst, SA | 1 |
| Herrmann, H | 1 |
| Omary, MB | 2 |
| Fowley, C | 1 |
| Nomikou, N | 1 |
| McHale, AP | 1 |
| McCaughan, B | 1 |
| Callan, JF | 1 |
| Patel, D | 1 |
| Alhawaj, R | 1 |
| Wolin, MS | 1 |
| Zhang, L | 1 |
| Zhang, Y | 1 |
| Zhong, W | 1 |
| Di, C | 1 |
| Lin, X | 1 |
| Xia, Z | 1 |
| Yamamoto, J | 1 |
| Ogura, S | 1 |
| Shimajiri, S | 1 |
| Nakano, Y | 1 |
| Akiba, D | 1 |
| Kitagawa, T | 1 |
| Ueta, K | 1 |
| Tanaka, T | 1 |
| Nishizawa, S | 1 |
| Balestra, GM | 1 |
| Mik, EG | 1 |
| Eerbeek, O | 1 |
| Specht, PA | 1 |
| van der Laarse, WJ | 1 |
| Zuurbier, CJ | 1 |
| Guo, HW | 1 |
| Lin, LT | 1 |
| Chen, PH | 1 |
| Ho, MH | 1 |
| Huang, WT | 1 |
| Lee, YJ | 1 |
| Chiou, SH | 1 |
| Hsieh, YS | 1 |
| Dong, CY | 1 |
| Wang, HW | 1 |
| Khan, HB | 1 |
| Vani, S | 1 |
| Palanivelu, S | 1 |
| Panchanadham, S | 1 |
| Shen, Y | 1 |
| Zhang, ZJ | 1 |
| Zhu, MD | 1 |
| Jiang, BC | 1 |
| Yang, T | 1 |
| Gao, YJ | 1 |
| Elenbaas, JS | 1 |
| Liu, Y | 1 |
| Lentz, SI | 1 |
| Nelson, B | 1 |
| Hoenerhoff, MJ | 1 |
| Shavit, JA | 1 |
| Bae, SJ | 1 |
| Lee, DS | 1 |
| Berezin, V | 1 |
| Kang, U | 1 |
| Lee, KH | 1 |
| Berrahmoune, S | 1 |
| Fotinos, N | 1 |
| Bezdetnaya, L | 1 |
| Lange, N | 2 |
| Guedenet, JC | 1 |
| Guillemin, F | 1 |
| D'Hallewin, MA | 1 |
| Martinez, Mdel C | 1 |
| Afonso, SG | 1 |
| Meiss, RP | 1 |
| Buzaleh, AM | 1 |
| Batlle, A | 1 |
| Fang, YP | 1 |
| Huang, YB | 1 |
| Wu, PC | 1 |
| Tsai, YH | 1 |
| Yamada, I | 1 |
| Masumoto, K | 1 |
| Ueda, Y | 1 |
| Hashimoto, K | 1 |
| Duchartre, Y | 1 |
| Petit, N | 1 |
| Moya, C | 1 |
| Lalanne, M | 1 |
| Dubus, P | 1 |
| Verneuil, Hd | 1 |
| Moreau-Gaudry, F | 1 |
| Richard, E | 1 |
| Croce, AC | 1 |
| Santamaria, G | 1 |
| De Simone, U | 1 |
| Lucchini, F | 1 |
| Freitas, I | 1 |
| Bottiroli, G | 1 |
| Kosaka, S | 2 |
| Miyoshi, N | 1 |
| Akilov, OE | 2 |
| Kawana, S | 1 |
| Lyoumi, S | 1 |
| Abitbol, M | 1 |
| Rainteau, D | 1 |
| Karim, Z | 1 |
| Bernex, F | 1 |
| Oustric, V | 1 |
| Millot, S | 1 |
| Lettéron, P | 1 |
| Heming, N | 1 |
| Guillmot, L | 1 |
| Montagutelli, X | 1 |
| Berdeaux, G | 1 |
| Poupon, R | 1 |
| Deybach, JC | 1 |
| Beaumont, C | 1 |
| Charoenbanpachon, S | 1 |
| Krasieva, T | 1 |
| Ebihara, A | 1 |
| Osann, K | 1 |
| Wilder-Smith, P | 1 |
| Lüdicke, F | 1 |
| Gabrecht, T | 1 |
| Wagnières, G | 1 |
| Van Den Bergh, H | 1 |
| Berclaz, L | 1 |
| Major, AL | 2 |
| Zaak, D | 1 |
| Sroka, R | 1 |
| Stocker, S | 2 |
| Bise, K | 1 |
| Lein, M | 1 |
| Höppner, M | 1 |
| Frimberger, D | 1 |
| Schneede, P | 1 |
| Reich, O | 1 |
| Kriegmair, M | 1 |
| Knüchel, R | 1 |
| Baumgartner, R | 1 |
| Hofstetter, A | 1 |
| Neumann, NJ | 1 |
| Hanneken, S | 1 |
| Ruzicka, T | 1 |
| Lehmann, P | 1 |
| Devesa, I | 1 |
| Ferrándiz, ML | 1 |
| Guillén, I | 1 |
| Cerdá, JM | 1 |
| Alcaraz, MJ | 1 |
| Courrol, LC | 1 |
| de Oliveira Silva, FR | 1 |
| Coutinho, EL | 1 |
| Piccoli, MF | 1 |
| Mansano, RD | 1 |
| Vieira Júnior, ND | 1 |
| Schor, N | 1 |
| Bellini, MH | 1 |
| O'Riordan, K | 1 |
| Forster, TH | 1 |
| Wyler, S | 1 |
| Ruszat, R | 1 |
| Gasser, TC | 1 |
| Bachmann, A | 1 |
| Anstey, AV | 1 |
| Hift, RJ | 1 |
| Conway, CL | 1 |
| Walker, I | 1 |
| Bell, A | 1 |
| Roberts, DJ | 1 |
| Brown, SB | 1 |
| Vernon, DI | 1 |
| Regula, J | 1 |
| Ravi, B | 1 |
| Bedwell, J | 1 |
| MacRobert, AJ | 1 |
| Bown, SG | 1 |
| Gottsch, JD | 1 |
| Bynoe, LA | 1 |
| Harlan, JB | 1 |
| Rencs, EV | 1 |
| Green, WR | 1 |
| Rose, GS | 1 |
| Chapman, CF | 1 |
| Hiserodt, JC | 1 |
| Tromberg, BJ | 1 |
| Krasieva, TB | 1 |
| Tadir, Y | 1 |
| Haller, U | 1 |
| DiSaia, PJ | 1 |
| Berns, MW | 1 |
| Vonarx, V | 1 |
| Eleouet, S | 1 |
| Carre, J | 1 |
| Ioss, P | 1 |
| Gouyette, A | 1 |
| Leray, AM | 1 |
| Merle, C | 1 |
| Lajat, Y | 1 |
| Patrice, T | 1 |
| Xiao, Z | 1 |
| Miller, GG | 1 |
| McCallum, TJ | 1 |
| Brown, KM | 1 |
| Lown, JW | 1 |
| Tulip, J | 1 |
| Moore, RB | 1 |
| Stummer, W | 1 |
| Novotny, A | 1 |
| Heimann, A | 1 |
| Sauer, O | 1 |
| Kempski, O | 1 |
| Plesnila, N | 1 |
| Wietzorrek, J | 1 |
| Reulen, HJ | 1 |
| Gibson, SL | 1 |
| Anderson, LT | 1 |
| Havens, JJ | 1 |
| Hilf, R | 1 |
| Childs, S | 1 |
| Weinstein, BM | 1 |
| Mohideen, MA | 1 |
| Donohue, S | 1 |
| Bonkovsky, H | 1 |
| Fishman, MC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol[NCT01533376] | Phase 1 | 3 participants (Actual) | Interventional | 2012-02-29 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for protoporphyrin ix and Disease Models, Animal
| Article | Year |
|---|---|
Sonodynamic Therapy for Gliomas. Perspectives and Prospects of Selective Sonosensitization of Glioma Cells.
Topics: Aminolevulinic Acid; Animals; Diagnostic Imaging; Disease Models, Animal; Glioma; Humans; Light; Pro | 2019 |
["... The better to see you with"--phothodynamic diagnostic in superficial bladder cancer].
Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Carcinoma in Situ; Carcinoma, Papillary; | 2007 |
Liver disease in erythropoietic protoporphyria: insights and implications for management.
Topics: Animals; Disease Models, Animal; Humans; Liver Diseases; Liver Transplantation; Pedigree; Protoporph | 2007 |
45 other studies available for protoporphyrin ix and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Results of a pilot study of isoniazid in patients with erythropoietic protoporphyria.
Topics: 5-Aminolevulinate Synthetase; Anemia, Sideroblastic; Animals; Disease Models, Animal; Female; Humans | 2019 |
Characterization of plasma-derived protoporphyrin-IX-positive extracellular vesicles following 5-ALA use in patients with malignant glioma.
Topics: Adult; Aged; Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Disease Models, Animal; | 2019 |
Activation of heme oxygenase-1 by Ginkgo biloba extract differentially modulates endothelial and smooth muscle-like progenitor cells for vascular repair.
Topics: Animals; Cell Movement; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; E | 2019 |
ZJ01, a Small Molecule Inhibitor of the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 (Keap1-Nrf2) Protein-Protein Interaction, Reduces Hyperoxic Acute Lung Injury in a Mouse Model.
Topics: Acute Lung Injury; Animals; Benzothiazoles; Disease Models, Animal; Heme Oxygenase-1; Hyperoxia; Kel | 2020 |
Prevention of adhesions post-abdominal surgery: Assessing the safety and efficacy of Chitogel with Deferiprone in a rat model.
Topics: Abdomen; Animals; Cecum; Chitosan; Deferiprone; Disease Models, Animal; Enterostomy; Gels; Kaolin; P | 2021 |
5-aminolaevulinic acid (5-ALA) accumulates in GIST-T1 cells and photodynamic diagnosis using 5-ALA identifies gastrointestinal stromal tumors (GISTs) in xenograft tumor models.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Disease Models, Animal; Female; Flow Cytometry; Fluo | 2021 |
Fluorouracil Enhances Photodynamic Therapy of Squamous Cell Carcinoma via a p53-Independent Mechanism that Increases Protoporphyrin IX levels and Tumor Cell Death.
Topics: Animals; Biosynthetic Pathways; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cell Prolife | 2017 |
Lamin aggregation is an early sensor of porphyria-induced liver injury.
Topics: Animals; Disease Models, Animal; Fatty Liver; Ferrochelatase; GTP-Binding Proteins; Hep G2 Cells; Hu | 2013 |
Extending the tissue penetration capability of conventional photosensitisers: a carbon quantum dot-protoporphyrin IX conjugate for use in two-photon excited photodynamic therapy.
Topics: Animals; Carbon; Cell Survival; Disease Models, Animal; Fibrosarcoma; Fluorescence Resonance Energy | 2013 |
Exposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxide.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Antihypertensive Agents; Aorta; Cell Adhesion Molecules | 2014 |
Heme oxygenase-1 ameliorates dextran sulfate sodium-induced acute murine colitis by regulating Th17/Treg cell balance.
Topics: Acute Disease; Animals; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Female; Forkhead Tr | 2014 |
5-aminolevulinic acid-induced protoporphyrin IX with multi-dose ionizing irradiation enhances host antitumor response and strongly inhibits tumor growth in experimental glioma in vivo.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cytotoxicity, | 2015 |
Increased in vivo mitochondrial oxygenation with right ventricular failure induced by pulmonary arterial hypertension: mitochondrial inhibition as driver of cardiac failure?
Topics: Administration, Inhalation; Animals; Arterial Pressure; Cardiotonic Agents; Disease Models, Animal; | 2015 |
Vitamin D enhances the efficacy of photodynamic therapy in a murine model of breast cancer.
Topics: Animals; Breast Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; | 2015 |
Low-fluence rate, long duration photodynamic therapy in glioma mouse model using organic light emitting diode (OLED).
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Glioblastoma; Humans; Mice; Mice, Nude; Photoc | 2015 |
Erythrocyte Protoporphyrin Fluorescence as a Biomarker to Monitor the Anticancer Effect of Semecarpus Anacardium in DMBA Induced Mammary Carcinoma Rat Model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antioxidants; Biomarkers; Carcinogens; Disease Models, An | 2015 |
Exogenous induction of HO-1 alleviates vincristine-induced neuropathic pain by reducing spinal glial activation in mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Disease Models, | 2015 |
A precursor-inducible zebrafish model of acute protoporphyria with hepatic protein aggregation and multiorganelle stress.
Topics: Aminolevulinic Acid; Animals; Deferoxamine; Disease Models, Animal; Genetic Predisposition to Diseas | 2016 |
Multispectral autofluorescence imaging for detection of cervical lesions: A preclinical study.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Disease Models, Animal; Female; Human papillomavirus | 2016 |
Analysis of differential PDT effect in rat bladder tumor models according to concentrations of intravesical hexyl-aminolevulinate.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Disease Models | 2008 |
Hepatic damage and oxidative stress induced by Griseofulvin in mice.
Topics: Animals; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 | 2009 |
Topical delivery of 5-aminolevulinic acid-encapsulated ethosomes in a hyperproliferative skin animal model using the CLSM technique to evaluate the penetration behavior.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Chemistry, Pharmaceutical; Disease Models, | 2009 |
Photodynamic therapy with intradermal administration of 5-aminolevulinic acid for port-wine stains.
Topics: Aminolevulinic Acid; Animals; Chickens; Disease Models, Animal; Female; Injections, Intradermal; Inj | 2010 |
Neonatal bone marrow transplantation prevents liver disease in a murine model of erythropoietic protoporphyria.
Topics: Animals; Animals, Newborn; Bone Marrow Transplantation; Busulfan; Disease Models, Animal; Disease Pr | 2011 |
Naturally-occurring porphyrins in a spontaneous-tumour bearing mouse model.
Topics: Animals; Disease Models, Animal; Female; Fluorometry; Iron; Liver; Mammary Neoplasms, Experimental; | 2011 |
Targeting of sebaceous glands by δ-aminolevulinic acid-based photodynamic therapy: An in vivo study.
Topics: Acne Vulgaris; Aminolevulinic Acid; Animals; Disease Models, Animal; Dose-Response Relationship, Dru | 2011 |
Protoporphyrin retention in hepatocytes and Kupffer cells prevents sclerosing cholangitis in erythropoietic protoporphyria mouse model.
Topics: Animals; Bile Acids and Salts; Cholangitis, Sclerosing; Cholesterol; Disease Models, Animal; Ferroch | 2011 |
Acceleration of ALA-induced PpIX fluorescence development in the oral mucosa.
Topics: Administration, Topical; Aminolevulinic Acid; Analysis of Variance; Animals; Carcinoma, Squamous Cel | 2003 |
Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study.
Topics: Aminolevulinic Acid; Animals; Diagnostic Techniques and Procedures; Disease Models, Animal; Drug Eva | 2003 |
Photodynamic therapy of prostate cancer by means of 5-aminolevulinic acid-induced protoporphyrin IX - in vivo experiments on the dunning rat tumor model.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Male; Photochemotherapy; Prostatic Neoplasms; | 2004 |
Phototoxicity of exogenous protoporphyrin IX and delta-aminolevulinic acid in the photo hen's egg test.
Topics: Aminolevulinic Acid; Animals; Chick Embryo; Dermatitis, Phototoxic; Disease Models, Animal; Forecast | 2004 |
Potential role of heme oxygenase-1 in the progression of rat adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Cyclooxygenase 2; Disease Models, Animal; Enzyme Inhibitors; Heat- | 2005 |
Study of blood porphyrin spectral profile for diagnosis of tumor progression.
Topics: Animals; Carcinoma, Renal Cell; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Human | 2007 |
Parasiticidal effect of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis is indirect and mediated through the killing of the host cells.
Topics: Aminolevulinic Acid; Animals; Cell Line, Transformed; Disease Models, Animal; Ear, External; Interle | 2007 |
In vivo and in vitro characterisation of a protoporphyrin IX-cyclic RGD peptide conjugate for use in photodynamic therapy.
Topics: Animals; Binding Sites; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Ass | 2008 |
Photodynamic therapy using 5-aminolaevulinic acid for experimental pancreatic cancer--prolonged animal survival.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Cricetinae; Disease Models, Animal; Female; Heme | 1994 |
Light-induced deposits in Bruch's membrane of protoporphyric mice.
Topics: Animals; Bruch Membrane; Capillaries; Choroid; Disease Models, Animal; Extracellular Matrix; Griseof | 1993 |
In vivo fluorescence detection of ovarian cancer in the NuTu-19 epithelial ovarian cancer animal model using 5-aminolevulinic acid (ALA).
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Epithelium; Feasibility Studies; Female; Fluor | 1997 |
Potential efficacy of a delta 5-aminolevulinic acid bioadhesive gel formulation for the photodynamic treatment of lesions of the gastrointestinal tract in mice.
Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Biocompatible Materials; Disease Models, Animal; Fi | 1997 |
Biodistribution of Photofrin II and 5-aminolevulinic acid-induced protoporphyrin IX in normal rat bladder and bladder tumor models: implications for photodynamic therapy.
Topics: Aminolevulinic Acid; Animals; Dihematoporphyrin Ether; Disease Models, Animal; Female; Photochemothe | 1998 |
In vitro and in vivo porphyrin accumulation by C6 glioma cells after exposure to 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Glioma; Humans; Male; Photosensitizing Agents; | 1998 |
Effect of estrogenic perturbations on delta-aminolevulinic acid-induced porphobilinogen deaminase and protoporphyrin IX levels in rat Harderian glands, liver, and R3230AC tumors.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Estrogen Antagonists; Estrogens; Female; Harde | 1999 |
Zebrafish dracula encodes ferrochelatase and its mutation provides a model for erythropoietic protoporphyria.
Topics: Animals; Disease Models, Animal; Ferrochelatase; Hemolysis; Humans; Light; Liver Diseases; Mutation; | 2000 |