protoporphyrin ix has been researched along with Carcinoma in Situ in 11 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Carcinoma in Situ: A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-aminolevulinic acid mediated changes in tissue specific fluorescence were studied in bladder cancer." | 7.72 | Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid. ( Christopher, C; Hoon, TP; Lau, W; Manivasager, V; Olivo, M, 2003) |
| "5-aminolevulinic acid mediated changes in tissue specific fluorescence were studied in bladder cancer." | 3.72 | Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid. ( Christopher, C; Hoon, TP; Lau, W; Manivasager, V; Olivo, M, 2003) |
| "A major problem diagnosing bladder cancer using conventional white-light cystoscopy is that flat and tiny papillary neoplasms can be overlooked." | 2.70 | Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms. ( Chai, SE; Choi, HY; Hong, JH; Jeon, SS; Kang, I, 2001) |
| "Bladder cancer is the most common tumor of the urinary tract, with a worldwide incidence of 8." | 2.49 | Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over. ( Ambrosini, E; Frea, B; Giona, S; Gontero, P; Gurioli, A; Oderda, M; Peraldo, F; Soria, F, 2013) |
| "Barrett's esophagus is strongly associated with adenocarcinoma." | 1.32 | Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid. ( Dorta, G; Felley, C; Fontolliet, C; Gabrecht, T; Grosjean, P; Jornod, P; Lange, N; Monnier, P; Stepinac, T; van den Bergh, H; vanMelle, G; Wagnières, G, 2003) |
| "24 patients suffering from oral cancer were included in this investigation." | 1.31 | Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies. ( Arbogast, S; Baumgartner, R; Betz, C; Grevers, G; Leunig, A; Mehlmann, M; Stepp, H, 2001) |
| "The prognosis of superficial bladder cancer in terms of local recurrence and transformation into invasive cancer is related to the multiplicity of tumor sites and the concomitant presence of "flat" tumours, such as dysplasia and carcinoma in situ." | 1.30 | [The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder]. ( Forrer, M; Graber, P; Guillou, L; Jichlinski, P; Leisinger, HJ; Mizeret, J; Schmidlin, F; Van den Bergh, H; Wagniéres, G, 1997) |
| "Following transurethral resection of bladder cancer, the fate of patients is clearly related to the presence or absence of precancerous or malignant lesions in the remaining mucosa." | 1.29 | [Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid]. ( Baumgartner, R; Ehsan, A; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Lumper, W; Steinbach, P, 1994) |
| "5-Aminolevulinic acid was instilled prior to cystoscopy and biopsies were taken of lesions that were either fluorescing or nonfluorescing." | 1.29 | Intravesical instillation of 5-aminolevulinic acid: the fluorescent metabolite is limited to urothelial cells. ( Baumgartner, R; Hofstädter, F; Knüchel, R; Kriegmair, M; Steinbach, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soria, F | 1 |
| Gurioli, A | 1 |
| Peraldo, F | 1 |
| Oderda, M | 1 |
| Giona, S | 1 |
| Ambrosini, E | 1 |
| Frea, B | 1 |
| Gontero, P | 1 |
| Olivo, M | 1 |
| Lau, W | 1 |
| Manivasager, V | 1 |
| Hoon, TP | 1 |
| Christopher, C | 1 |
| Stepinac, T | 1 |
| Felley, C | 1 |
| Jornod, P | 1 |
| Lange, N | 1 |
| Gabrecht, T | 1 |
| Fontolliet, C | 1 |
| Grosjean, P | 1 |
| vanMelle, G | 1 |
| van den Bergh, H | 2 |
| Monnier, P | 1 |
| Wagnières, G | 2 |
| Dorta, G | 1 |
| Endlicher, E | 1 |
| Gelbmann, CM | 1 |
| Knüchel, R | 3 |
| Fürst, A | 1 |
| Szeimies, RM | 1 |
| Gölder, SK | 1 |
| Schölmerich, J | 1 |
| Lottner, C | 1 |
| Messmann, H | 1 |
| Forster, TH | 1 |
| Wyler, S | 1 |
| Ruszat, R | 1 |
| Gasser, TC | 1 |
| Bachmann, A | 1 |
| Kriegmair, M | 2 |
| Baumgartner, R | 4 |
| Ehsan, A | 1 |
| Steinbach, P | 2 |
| Lumper, W | 1 |
| Hofstädter, F | 2 |
| Hofstetter, A | 1 |
| Jichlinski, P | 1 |
| Forrer, M | 1 |
| Mizeret, J | 1 |
| Guillou, L | 1 |
| Schmidlin, F | 1 |
| Graber, P | 1 |
| Leisinger, HJ | 1 |
| Leunig, A | 1 |
| Mehlmann, M | 1 |
| Betz, C | 1 |
| Stepp, H | 2 |
| Arbogast, S | 1 |
| Grevers, G | 1 |
| Xiang, W | 1 |
| Weingandt, H | 1 |
| Liessmann, F | 1 |
| Klein, S | 1 |
| Hillemanns, P | 1 |
| Jeon, SS | 1 |
| Kang, I | 1 |
| Hong, JH | 1 |
| Choi, HY | 1 |
| Chai, SE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Correlation of Surgical Colorectal Cancer Specimen Pathology With the Fluorescence of Photodynamic Diagnostics (PDD): a Clinical Pilot Study[NCT03272659] | Phase 2 | 0 participants (Actual) | Interventional | 2018-04-01 | Withdrawn (stopped due to Long process and due to strict deadline, project was stopped.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for protoporphyrin ix and Carcinoma in Situ
| Article | Year |
|---|---|
Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; False Negative Rea | 2013 |
["... The better to see you with"--phothodynamic diagnostic in superficial bladder cancer].
Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Carcinoma in Situ; Carcinoma, Papillary; | 2007 |
1 trial available for protoporphyrin ix and Carcinoma in Situ
| Article | Year |
|---|---|
Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluoresc | 2001 |
8 other studies available for protoporphyrin ix and Carcinoma in Situ
| Article | Year |
|---|---|
Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid.
Topics: Administration, Intravesical; Aminolevulinic Acid; Biomarkers, Tumor; Carcinoma in Situ; Carcinoma, | 2003 |
Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid.
Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Carcinoma in Situ; Esopha | 2003 |
Hexaminolevulinate-induced fluorescence endoscopy in patients with rectal adenoma and cancer: a pilot study.
Topics: Adenoma; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Cell Transformatio | 2004 |
[Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid].
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma | 1994 |
Intravesical instillation of 5-aminolevulinic acid: the fluorescent metabolite is limited to urothelial cells.
Topics: Administration, Intravesical; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Papillary; Cell Lin | 1994 |
[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder].
Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carci | 1997 |
Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fluorescence; Humans; Microscopy, | 2001 |
Photodynamic effects induced by aminolevulinic acid esters on human cervical carcinoma cells in culture.
Topics: Aminolevulinic Acid; Annexin A5; Apoptosis; Carcinoma in Situ; Cell Membrane; Cell Survival; Dose-Re | 2001 |