Page last updated: 2024-11-03

protoporphyrin ix and Carcinoma in Situ

protoporphyrin ix has been researched along with Carcinoma in Situ in 11 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Carcinoma in Situ: A lesion with cytological characteristics associated with invasive carcinoma but the tumor cells are confined to the epithelium of origin, without invasion of the basement membrane.

Research Excerpts

ExcerptRelevanceReference
"5-aminolevulinic acid mediated changes in tissue specific fluorescence were studied in bladder cancer."7.72Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid. ( Christopher, C; Hoon, TP; Lau, W; Manivasager, V; Olivo, M, 2003)
"5-aminolevulinic acid mediated changes in tissue specific fluorescence were studied in bladder cancer."3.72Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid. ( Christopher, C; Hoon, TP; Lau, W; Manivasager, V; Olivo, M, 2003)
"A major problem diagnosing bladder cancer using conventional white-light cystoscopy is that flat and tiny papillary neoplasms can be overlooked."2.70Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms. ( Chai, SE; Choi, HY; Hong, JH; Jeon, SS; Kang, I, 2001)
"Bladder cancer is the most common tumor of the urinary tract, with a worldwide incidence of 8."2.49Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over. ( Ambrosini, E; Frea, B; Giona, S; Gontero, P; Gurioli, A; Oderda, M; Peraldo, F; Soria, F, 2013)
"Barrett's esophagus is strongly associated with adenocarcinoma."1.32Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid. ( Dorta, G; Felley, C; Fontolliet, C; Gabrecht, T; Grosjean, P; Jornod, P; Lange, N; Monnier, P; Stepinac, T; van den Bergh, H; vanMelle, G; Wagnières, G, 2003)
"24 patients suffering from oral cancer were included in this investigation."1.31Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies. ( Arbogast, S; Baumgartner, R; Betz, C; Grevers, G; Leunig, A; Mehlmann, M; Stepp, H, 2001)
"The prognosis of superficial bladder cancer in terms of local recurrence and transformation into invasive cancer is related to the multiplicity of tumor sites and the concomitant presence of "flat" tumours, such as dysplasia and carcinoma in situ."1.30[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder]. ( Forrer, M; Graber, P; Guillou, L; Jichlinski, P; Leisinger, HJ; Mizeret, J; Schmidlin, F; Van den Bergh, H; Wagniéres, G, 1997)
"Following transurethral resection of bladder cancer, the fate of patients is clearly related to the presence or absence of precancerous or malignant lesions in the remaining mucosa."1.29[Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid]. ( Baumgartner, R; Ehsan, A; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Lumper, W; Steinbach, P, 1994)
"5-Aminolevulinic acid was instilled prior to cystoscopy and biopsies were taken of lesions that were either fluorescing or nonfluorescing."1.29Intravesical instillation of 5-aminolevulinic acid: the fluorescent metabolite is limited to urothelial cells. ( Baumgartner, R; Hofstädter, F; Knüchel, R; Kriegmair, M; Steinbach, P, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's7 (63.64)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Soria, F1
Gurioli, A1
Peraldo, F1
Oderda, M1
Giona, S1
Ambrosini, E1
Frea, B1
Gontero, P1
Olivo, M1
Lau, W1
Manivasager, V1
Hoon, TP1
Christopher, C1
Stepinac, T1
Felley, C1
Jornod, P1
Lange, N1
Gabrecht, T1
Fontolliet, C1
Grosjean, P1
vanMelle, G1
van den Bergh, H2
Monnier, P1
Wagnières, G2
Dorta, G1
Endlicher, E1
Gelbmann, CM1
Knüchel, R3
Fürst, A1
Szeimies, RM1
Gölder, SK1
Schölmerich, J1
Lottner, C1
Messmann, H1
Forster, TH1
Wyler, S1
Ruszat, R1
Gasser, TC1
Bachmann, A1
Kriegmair, M2
Baumgartner, R4
Ehsan, A1
Steinbach, P2
Lumper, W1
Hofstädter, F2
Hofstetter, A1
Jichlinski, P1
Forrer, M1
Mizeret, J1
Guillou, L1
Schmidlin, F1
Graber, P1
Leisinger, HJ1
Leunig, A1
Mehlmann, M1
Betz, C1
Stepp, H2
Arbogast, S1
Grevers, G1
Xiang, W1
Weingandt, H1
Liessmann, F1
Klein, S1
Hillemanns, P1
Jeon, SS1
Kang, I1
Hong, JH1
Choi, HY1
Chai, SE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Correlation of Surgical Colorectal Cancer Specimen Pathology With the Fluorescence of Photodynamic Diagnostics (PDD): a Clinical Pilot Study[NCT03272659]Phase 20 participants (Actual)Interventional2018-04-01Withdrawn (stopped due to Long process and due to strict deadline, project was stopped.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for protoporphyrin ix and Carcinoma in Situ

ArticleYear
Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over.
    Urologia, 2013, Volume: 80 Spec No 1

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; False Negative Rea

2013
["... The better to see you with"--phothodynamic diagnostic in superficial bladder cancer].
    Praxis, 2007, Oct-17, Volume: 96, Issue:42

    Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Carcinoma in Situ; Carcinoma, Papillary;

2007

Trials

1 trial available for protoporphyrin ix and Carcinoma in Situ

ArticleYear
Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms.
    Journal of endourology, 2001, Volume: 15, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluoresc

2001

Other Studies

8 other studies available for protoporphyrin ix and Carcinoma in Situ

ArticleYear
Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid.
    International journal of oncology, 2003, Volume: 22, Issue:3

    Topics: Administration, Intravesical; Aminolevulinic Acid; Biomarkers, Tumor; Carcinoma in Situ; Carcinoma,

2003
Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid.
    Endoscopy, 2003, Volume: 35, Issue:8

    Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Carcinoma in Situ; Esopha

2003
Hexaminolevulinate-induced fluorescence endoscopy in patients with rectal adenoma and cancer: a pilot study.
    Gastrointestinal endoscopy, 2004, Volume: 60, Issue:3

    Topics: Adenoma; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Cell Transformatio

2004
[Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid].
    Der Urologe. Ausg. A, 1994, Volume: 33, Issue:4

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma

1994
Intravesical instillation of 5-aminolevulinic acid: the fluorescent metabolite is limited to urothelial cells.
    Urology, 1994, Volume: 44, Issue:5

    Topics: Administration, Intravesical; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Papillary; Cell Lin

1994
[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder].
    Annales d'urologie, 1997, Volume: 31, Issue:1

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carci

1997
Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies.
    Journal of photochemistry and photobiology. B, Biology, 2001, Volume: 60, Issue:1

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fluorescence; Humans; Microscopy,

2001
Photodynamic effects induced by aminolevulinic acid esters on human cervical carcinoma cells in culture.
    Photochemistry and photobiology, 2001, Volume: 74, Issue:4

    Topics: Aminolevulinic Acid; Annexin A5; Apoptosis; Carcinoma in Situ; Cell Membrane; Cell Survival; Dose-Re

2001