protoporphyrin ix has been researched along with Carcinoma, Epidermoid in 46 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Excerpt | Relevance | Reference |
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"Although having shown promising clinical outcomes, the effectiveness of 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) for squamous cell carcinoma (SCC) and glioblastoma remains to be improved." | 7.91 | Methadone enhances the effectiveness of 5-aminolevulinic acid-based photodynamic therapy for squamous cell carcinoma and glioblastoma in vitro. ( Buchner, A; Gederaas, OA; Pohla, H; Pongratz, T; Rühm, A; Shi, L; Sroka, R; Stepp, H; Wang, X; Zhang, L; Zimmermann, W, 2019) |
" In this study, we used 5-aminolevulinic (ALA) acid and 3 water soluble photosensitizers-PP(Arg)(2), PP(Ser)(2)Arg(2), PP(Ala)(2)Arg(2), all diamino acid derivatives of protoporphyrin IX-to treat benign papillomas in FVB/N mice induced by 7,12-dimethylbenz(a)anthracene (DMBA)-12-O-tetradecanoyl-phorbol-13-acetate (TPA)." | 7.75 | Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin. ( Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R, 2009) |
"Although having shown promising clinical outcomes, the effectiveness of 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) for squamous cell carcinoma (SCC) and glioblastoma remains to be improved." | 3.91 | Methadone enhances the effectiveness of 5-aminolevulinic acid-based photodynamic therapy for squamous cell carcinoma and glioblastoma in vitro. ( Buchner, A; Gederaas, OA; Pohla, H; Pongratz, T; Rühm, A; Shi, L; Sroka, R; Stepp, H; Wang, X; Zhang, L; Zimmermann, W, 2019) |
" In this study, we used 5-aminolevulinic (ALA) acid and 3 water soluble photosensitizers-PP(Arg)(2), PP(Ser)(2)Arg(2), PP(Ala)(2)Arg(2), all diamino acid derivatives of protoporphyrin IX-to treat benign papillomas in FVB/N mice induced by 7,12-dimethylbenz(a)anthracene (DMBA)-12-O-tetradecanoyl-phorbol-13-acetate (TPA)." | 3.75 | Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin. ( Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R, 2009) |
"Non-melanoma skin cancers are the most frequently occurring type of cancer worldwide." | 1.48 | An experimental investigation of a novel iron chelating protoporphyrin IX prodrug for the enhancement of photodynamic therapy. ( Anayo, L; Curnow, A; Magnussen, A; Perry, A; Wood, M, 2018) |
"Human head and neck cancer cells AMC-HN3 were treated with cisplatin- and ALA-mediated PDT individually, and also in combination." | 1.40 | Cisplatin enhances the efficacy of 5-aminolevulinic acid mediated photodynamic therapy in human head and neck squamous cell carcinoma. ( Ahn, JC; Biswas, R; Chung, PS; Lee, YK; Mondal, A, 2014) |
"(R)L-sulforaphane (SF) is a compound that protects against erythema, but it can also induce DNA fragmentation that leads to cell death by apoptosis." | 1.35 | Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy. ( Juzeniene, A; Mikolajewska, P; Moan, J, 2008) |
"Etretinate-pretreated cells underwent apoptosis in response to ALA-based PDT." | 1.35 | Etretinate enhances the susceptibility of human skin squamous cell carcinoma cells to 5-aminolaevulic acid-based photodynamic therapy. ( Akita, Y; Ishida, N; Kuhara, T; Matsumoto, Y; Nakano, A; Takeo, T; Tamada, Y; Watanabe, D; Yamashita, N; Yanagishita, T, 2009) |
"Human prostate cancer (DU-145) and squamous carcinoma (A431) cells were used as experimental model." | 1.35 | Diamino acid derivatives of PpIX as potential photosensitizers for photodynamic therapy of squamous cell carcinoma and prostate cancer: in vitro studies. ( Glosnicka, R; Graczyk, A; Juzeniene, A; Kwitniewski, M; Ma, LW; Moan, J, 2009) |
"Calcitriol pretreatment of the cells elevated their PpIX levels." | 1.35 | Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells. ( Cicarma, E; Juzeniene, A; Ma, LW; Moan, J; Tuorkey, M, 2009) |
"The prognosis of patients with oral cancer can be improved by early diagnosis." | 1.33 | Topical application of photofrin for photodynamic diagnosis of oral neoplasms. ( Chang, CJ; Wilder-Smith, P, 2005) |
"It will be the aim of further investigations to verify the optimal time of incubation and dosing of systemical 5-ALA application to enhance fluorescence contrasts and set the basis for fluorescence guided resections." | 1.31 | [Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid]. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Leunig, A, 2002) |
" We have investigated the effect of 5-ALA mediated PDT in combination with gamma-irradiation on the colony forming ability of several human head and neck tumour cell lines." | 1.31 | Effect of photodynamic therapy in combination with ionizing radiation on human squamous cell carcinoma cell lines of the head and neck. ( Allman, R; Cowburn, P; Mason, M, 2000) |
"24 patients suffering from oral cancer were included in this investigation." | 1.31 | Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies. ( Arbogast, S; Baumgartner, R; Betz, C; Grevers, G; Leunig, A; Mehlmann, M; Stepp, H, 2001) |
"In mice with squamous cell carcinoma, the in vivo expression of PpIX in the tumors was highest with ALA methyl ester, which was 1." | 1.31 | In vitro and in vivo expression of protoporphyrin IX induced by lipophilic 5-aminolevulinic acid derivatives. ( Ishibashi, A; Itoh, Y; Ninomiya, Y; Tajima, S, 2001) |
"Protoporphyrin IX fluorescence was detected in the oral mucosa of all patients after local application of 5-ALA." | 1.29 | Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity. ( Alwin, G; Baumgartner, R; Feyh, J; Gutmann, R; Leunig, A; Rick, K; Stepp, H, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 6 (13.04) | 18.2507 |
2000's | 19 (41.30) | 29.6817 |
2010's | 19 (41.30) | 24.3611 |
2020's | 2 (4.35) | 2.80 |
Authors | Studies |
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Schary, N | 1 |
Novak, B | 1 |
Kämper, L | 1 |
Yousf, A | 1 |
Lübbert, H | 1 |
León, D | 1 |
Buchegger, K | 1 |
Silva, R | 1 |
Riquelme, I | 1 |
Viscarra, T | 1 |
Mora-Lagos, B | 1 |
Zanella, L | 1 |
Schafer, F | 1 |
Kurachi, C | 1 |
Roa, JC | 1 |
Ili, C | 1 |
Brebi, P | 1 |
Anand, S | 2 |
Rollakanti, KR | 2 |
Brankov, N | 1 |
Brash, DE | 1 |
Hasan, T | 3 |
Maytin, EV | 3 |
Anayo, L | 1 |
Magnussen, A | 1 |
Perry, A | 1 |
Wood, M | 1 |
Curnow, A | 3 |
Shi, L | 1 |
Buchner, A | 1 |
Pohla, H | 1 |
Pongratz, T | 1 |
Rühm, A | 1 |
Zimmermann, W | 1 |
Gederaas, OA | 1 |
Zhang, L | 1 |
Wang, X | 1 |
Stepp, H | 5 |
Sroka, R | 1 |
Larisch, P | 1 |
Verwanger, T | 2 |
Onder, K | 1 |
Krammer, B | 2 |
Yamamoto, M | 1 |
Fujita, H | 1 |
Katase, N | 1 |
Inoue, K | 1 |
Nagatsuka, H | 1 |
Utsumi, K | 1 |
Sasaki, J | 1 |
Ohuchi, H | 1 |
Ahn, JC | 1 |
Biswas, R | 1 |
Mondal, A | 1 |
Lee, YK | 1 |
Chung, PS | 1 |
Blake, E | 1 |
Allen, J | 1 |
Xie, H | 1 |
Xie, Z | 1 |
Mousavi, M | 1 |
Bendsoe, N | 1 |
Brydegaard, M | 1 |
Axelsson, J | 1 |
Andersson-Engels, S | 1 |
Davis, SC | 2 |
Pogue, BW | 2 |
Bay, C | 1 |
Togsverd-Bo, K | 1 |
Lerche, CM | 1 |
Haedersdal, M | 1 |
de Souza, AL | 1 |
Marra, K | 1 |
Gunn, J | 1 |
Samkoe, KS | 1 |
Kanick, SC | 1 |
Chapman, MS | 1 |
Lima, CA | 1 |
Goulart, VP | 1 |
Bechara, EJ | 1 |
Correa, L | 1 |
Zezell, DM | 1 |
Mikolajewska, P | 1 |
Juzeniene, A | 4 |
Moan, J | 4 |
Ishida, N | 1 |
Watanabe, D | 1 |
Akita, Y | 1 |
Nakano, A | 1 |
Yamashita, N | 1 |
Kuhara, T | 1 |
Yanagishita, T | 1 |
Takeo, T | 1 |
Tamada, Y | 1 |
Matsumoto, Y | 1 |
Kwitniewski, M | 2 |
Ma, LW | 3 |
Glosnicka, R | 2 |
Graczyk, A | 2 |
Cicarma, E | 1 |
Tuorkey, M | 1 |
Jankowski, D | 1 |
Jaskiewicz, K | 1 |
Dziadziuszko, H | 1 |
Peksa, R | 1 |
Kunikowska, D | 1 |
Kwasny, M | 1 |
Kaliszewski, M | 1 |
Moon, YH | 1 |
Park, JH | 1 |
Kim, SA | 1 |
Lee, JB | 1 |
Ahn, SG | 1 |
Yoon, JH | 1 |
Liutkeviciūte-Navickiene, J | 1 |
Mordas, A | 1 |
Simkute, S | 1 |
Bloznelyte-Plesniene, L | 1 |
Uekusa, M | 1 |
Omura, K | 1 |
Nakajima, Y | 1 |
Hasegawa, S | 1 |
Harada, H | 1 |
Morita, KI | 1 |
Tsuda, H | 1 |
Mallia, RJ | 1 |
Subhash, N | 1 |
Sebastian, P | 1 |
Kumar, R | 1 |
Thomas, SS | 1 |
Mathews, A | 1 |
Madhavan, J | 1 |
Lee, CY | 1 |
Kim, KH | 1 |
Kim, YH | 1 |
Milla, LN | 1 |
Cogno, IS | 1 |
Rodríguez, ME | 1 |
Sanz-Rodríguez, F | 1 |
Zamarrón, A | 1 |
Gilaberte, Y | 1 |
Carrasco, E | 1 |
Rivarola, VA | 1 |
Juarranz, A | 1 |
Lv, Y | 1 |
Fang, M | 1 |
Zheng, J | 1 |
Yang, B | 1 |
Li, H | 1 |
Xiuzigao, Z | 1 |
Song, W | 1 |
Chen, Y | 1 |
Cao, W | 1 |
Gaál, M | 1 |
Kui, R | 1 |
Hunyadi, Z | 1 |
Kemény, L | 1 |
Gyulai, R | 1 |
Sanovic, R | 1 |
Aberger, F | 1 |
Frischauf, AM | 1 |
Leunig, A | 5 |
Betz, CS | 3 |
Heinrich, P | 1 |
Janda, P | 2 |
Baumgartner, R | 5 |
Charoenbanpachon, S | 1 |
Krasieva, T | 1 |
Ebihara, A | 1 |
Osann, K | 1 |
Wilder-Smith, P | 2 |
Chang, CJ | 1 |
Ji, Z | 1 |
Yang, G | 1 |
Vasovic, V | 1 |
Cunderlikova, B | 1 |
Suo, Z | 1 |
Nesland, JM | 1 |
Peng, Q | 1 |
Ogasawara, T | 1 |
Miyoshi, N | 1 |
Sano, K | 1 |
Kitagawa, Y | 1 |
Yamada, T | 1 |
Ogawa, T | 1 |
Miyauchi, K | 1 |
Kinoshita, H | 1 |
Smits, T | 1 |
Kleinpenning, MM | 1 |
Blokx, WA | 1 |
van de Kerkhof, PC | 1 |
van Erp, PE | 1 |
Gerritsen, MJ | 1 |
Pye, A | 1 |
Grant, WE | 1 |
Hopper, C | 1 |
MacRobert, AJ | 1 |
Speight, PM | 1 |
Bown, SG | 1 |
Iinuma, S | 1 |
Farshi, SS | 1 |
Ortel, B | 1 |
van der Veen, N | 1 |
de Bruijn, HS | 1 |
Berg, RJ | 1 |
Star, WM | 1 |
Rick, K | 1 |
Gutmann, R | 1 |
Alwin, G | 1 |
Feyh, J | 1 |
Lucroy, MD | 1 |
Edwards, BF | 1 |
Peavy, GM | 1 |
Krasieva, TB | 1 |
Griffey, SM | 1 |
Stiles, JB | 1 |
Madewell, BR | 1 |
Mehlmann, M | 2 |
Arbogast, S | 3 |
Grevers, G | 3 |
Allman, R | 1 |
Cowburn, P | 1 |
Mason, M | 1 |
Betz, C | 1 |
Ninomiya, Y | 1 |
Itoh, Y | 1 |
Tajima, S | 1 |
Ishibashi, A | 1 |
Kennedy, JC | 1 |
Pottier, RH | 1 |
Pross, DC | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Photodynamic Therapy for Treatment of Cutaneous Squamous Cell Carcinoma in Situ[NCT03025724] | 40 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for protoporphyrin ix and Carcinoma, Epidermoid
Article | Year |
---|---|
[Fluorescence diagnosis of non-melanoma skin cancer].
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Basal Cell; Carcinoma, Basosquamous; Carcinoma, Squamous | 2012 |
1 trial available for protoporphyrin ix and Carcinoma, Epidermoid
Article | Year |
---|---|
Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Keratosis; Ph | 1990 |
44 other studies available for protoporphyrin ix and Carcinoma, Epidermoid
Article | Year |
---|---|
Identification and pharmacological modification of resistance mechanisms to protoporphyrin-mediated photodynamic therapy in human cutaneous squamous cell carcinoma cell lines.
Topics: Aminolevulinic Acid; ATP-Binding Cassette Transporters; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2022 |
Epigallocatechin Gallate Enhances MAL-PDT Cytotoxic Effect on PDT-Resistant Skin Cancer Squamous Cells.
Topics: Aminolevulinic Acid; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Cell Death; Cell H | 2020 |
Fluorouracil Enhances Photodynamic Therapy of Squamous Cell Carcinoma via a p53-Independent Mechanism that Increases Protoporphyrin IX levels and Tumor Cell Death.
Topics: Animals; Biosynthetic Pathways; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cell Prolife | 2017 |
An experimental investigation of a novel iron chelating protoporphyrin IX prodrug for the enhancement of photodynamic therapy.
Topics: Carcinoma, Squamous Cell; Cell Culture Techniques; Epithelial Cells; Fibroblasts; Humans; Iron Chela | 2018 |
Methadone enhances the effectiveness of 5-aminolevulinic acid-based photodynamic therapy for squamous cell carcinoma and glioblastoma in vitro.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Drug Synergi | 2019 |
In vitro analysis of photosensitizer accumulation for assessment of applicability of fluorescence diagnosis of squamous cell carcinoma of epidermolysis bullosa patients.
Topics: Anthracenes; Carcinoma, Squamous Cell; Cell Line, Tumor; Epidermolysis Bullosa; False Positive React | 2013 |
Improvement of the efficacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma HSC-4.
Topics: Amino Acid Chloromethyl Ketones; Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, S | 2013 |
Cisplatin enhances the efficacy of 5-aminolevulinic acid mediated photodynamic therapy in human head and neck squamous cell carcinoma.
Topics: Aminolevulinic Acid; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cel | 2014 |
The effects of protoporphyrin IX-induced photodynamic therapy with and without iron chelation on human squamous carcinoma cells cultured under normoxic, hypoxic and hyperoxic conditions.
Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Synergism; Humans; Iron Chelating Agents; Oxygen; P | 2013 |
Design and validation of a fiber optic point probe instrument for therapy guidance and monitoring.
Topics: Aminolevulinic Acid; Animals; Calibration; Carcinoma, Squamous Cell; Equipment Design; Fiber Optic T | 2014 |
Noninvasive Optical Imaging of UV-Induced Squamous Cell Carcinoma in Murine Skin: Studies of Early Tumor Development and Vitamin D Enhancement of Protoporphyrin IX Production.
Topics: Animals; Carcinoma, Squamous Cell; Fluorescence; Gene Expression Regulation, Neoplastic; Mice; Optic | 2015 |
Skin tumor development after UV irradiation and photodynamic therapy is unaffected by short-term pretreatment with 5-fluorouracil, imiquimod and calcipotriol. An experimental hairless mouse study.
Topics: Aminolevulinic Acid; Aminoquinolines; Animals; Calcitriol; Carcinoma, Squamous Cell; Female; Fluorou | 2016 |
Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose Fractio | 2016 |
Optimization and therapeutic effects of PDT mediated by ALA and MAL in the treatment of cutaneous malignant lesions: A comparative study.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Female; Mice; Photochemotherapy; Photosensit | 2016 |
Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy.
Topics: Aminolevulinic Acid; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Scree | 2008 |
Etretinate enhances the susceptibility of human skin squamous cell carcinoma cells to 5-aminolaevulic acid-based photodynamic therapy.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Squamous Cell; Cell Death; Dose-Response Relationship, Dr | 2009 |
Diamino acid derivatives of PpIX as potential photosensitizers for photodynamic therapy of squamous cell carcinoma and prostate cancer: in vitro studies.
Topics: Amino Acids, Diamino; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Screening Assays, Antitumor; | 2009 |
Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells.
Topics: Aminolevulinic Acid; Calcitriol; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2009 |
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Carcinogens; Carcinoma, Squamous Cel | 2009 |
Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma.
Topics: Aminolevulinic Acid; Blotting, Western; Carcinoma, Squamous Cell; Caspase 3; Cell Death; Cell Surviv | 2010 |
[Fluorescence diagnostics of skin tumors using 5-aminolevulinic acid and its methyl ester].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell | 2009 |
Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.
Topics: Amino Acids, Neutral; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Deferoxamine; Drug Co | 2010 |
In vivo temporal evolution of ALA-induced normalized fluorescence at different anatomical locations of oral cavity: application to improve cancer diagnostic contrast and potential.
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Squamous Cell; Diagnosis, Oral; Humans; Mou | 2010 |
The efficacy of photodynamic diagnosis in defining the lateral border between a tumor and a tumor-free area during Mohs micrographic surgery.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carci | 2010 |
Isolation and characterization of squamous carcinoma cells resistant to photodynamic therapy.
Topics: Aminolevulinic Acid; beta Catenin; Cadherins; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cel | 2011 |
Low-intensity ultrasound combined with 5-aminolevulinic acid administration in the treatment of human tongue squamous carcinoma.
Topics: Aminolevulinic Acid; Animals; Apoptosis; bcl-2-Associated X Protein; Calcium; Carcinoma, Squamous Ce | 2012 |
Gene expression pattern following photodynamic treatment of the carcinoma cell line A-431 analysed by cDNA arrays.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Squamous Cell; Cell Survival; Enzyme Induction; Gene Expr | 2002 |
[Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid].
Topics: Administration, Inhalation; Administration, Oral; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous C | 2002 |
Acceleration of ALA-induced PpIX fluorescence development in the oral mucosa.
Topics: Administration, Topical; Aminolevulinic Acid; Analysis of Variance; Animals; Carcinoma, Squamous Cel | 2003 |
Topical application of photofrin for photodynamic diagnosis of oral neoplasms.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cheek; Dihematoporphyrin Ether; Female; Fl | 2005 |
Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines.
Topics: Adenosine Triphosphate; Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; | 2006 |
Influence of administration methods on the accumulation of ALA-induced Pp-IX in mouse tongue tumors.
Topics: Administration, Oral; Administration, Topical; Aminolevulinic Acid; Animals; Carcinoma, Squamous Cel | 2006 |
Fluorescence diagnosis in keratinocytic intraepidermal neoplasias.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Proliferation; D | 2007 |
Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose-Response Relatio | 2007 |
Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid.
Topics: Administration, Oral; Aminolevulinic Acid; Carcinoma, Squamous Cell; Fluorescence; Humans; Laser The | 1993 |
A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Division; | 1994 |
Kinetics and localisation of PpIX fluorescence after topical and systemic ALA application, observed in skin and skin tumours of UVB-treated mice.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Female; Injections, | 1996 |
Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity.
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Squamous Cell; Endoscopy; Humans; Middle Ag | 1996 |
Preclinical study in cats of the pro-photosensitizer 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Biotransformation; Carcinoma, Squamous Cell; Cat Diseases; Cats; Cell | 1999 |
Detection of squamous cell carcinoma of the oral cavity by imaging 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
Topics: Adult; Aged; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Humans; Middle Aged; Mouth; Mout | 2000 |
Effect of photodynamic therapy in combination with ionizing radiation on human squamous cell carcinoma cell lines of the head and neck.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Combined Modality Therapy; | 2000 |
Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fluorescence; Humans; Microscopy, | 2001 |
In vitro and in vivo expression of protoporphyrin IX induced by lipophilic 5-aminolevulinic acid derivatives.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cells, Cultured; HeLa Cells; Humans; Keratin | 2001 |
A comparative study of normal inspection, autofluorescence and 5-ALA-induced PPIX fluorescence for oral cancer diagnosis.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Female; Fluor | 2002 |