Page last updated: 2024-11-03

protoporphyrin ix and Carcinoma, Epidermoid

protoporphyrin ix has been researched along with Carcinoma, Epidermoid in 46 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Research Excerpts

ExcerptRelevanceReference
"Although having shown promising clinical outcomes, the effectiveness of 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) for squamous cell carcinoma (SCC) and glioblastoma remains to be improved."7.91Methadone enhances the effectiveness of 5-aminolevulinic acid-based photodynamic therapy for squamous cell carcinoma and glioblastoma in vitro. ( Buchner, A; Gederaas, OA; Pohla, H; Pongratz, T; Rühm, A; Shi, L; Sroka, R; Stepp, H; Wang, X; Zhang, L; Zimmermann, W, 2019)
" In this study, we used 5-aminolevulinic (ALA) acid and 3 water soluble photosensitizers-PP(Arg)(2), PP(Ser)(2)Arg(2), PP(Ala)(2)Arg(2), all diamino acid derivatives of protoporphyrin IX-to treat benign papillomas in FVB/N mice induced by 7,12-dimethylbenz(a)anthracene (DMBA)-12-O-tetradecanoyl-phorbol-13-acetate (TPA)."7.75Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin. ( Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R, 2009)
"Although having shown promising clinical outcomes, the effectiveness of 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) for squamous cell carcinoma (SCC) and glioblastoma remains to be improved."3.91Methadone enhances the effectiveness of 5-aminolevulinic acid-based photodynamic therapy for squamous cell carcinoma and glioblastoma in vitro. ( Buchner, A; Gederaas, OA; Pohla, H; Pongratz, T; Rühm, A; Shi, L; Sroka, R; Stepp, H; Wang, X; Zhang, L; Zimmermann, W, 2019)
" In this study, we used 5-aminolevulinic (ALA) acid and 3 water soluble photosensitizers-PP(Arg)(2), PP(Ser)(2)Arg(2), PP(Ala)(2)Arg(2), all diamino acid derivatives of protoporphyrin IX-to treat benign papillomas in FVB/N mice induced by 7,12-dimethylbenz(a)anthracene (DMBA)-12-O-tetradecanoyl-phorbol-13-acetate (TPA)."3.75Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin. ( Dziadziuszko, H; Glosnicka, R; Graczyk, A; Jankowski, D; Jaskiewicz, K; Juzeniene, A; Kaliszewski, M; Kunikowska, D; Kwasny, M; Kwitniewski, M; Ma, LW; Moan, J; Peksa, R, 2009)
"Non-melanoma skin cancers are the most frequently occurring type of cancer worldwide."1.48An experimental investigation of a novel iron chelating protoporphyrin IX prodrug for the enhancement of photodynamic therapy. ( Anayo, L; Curnow, A; Magnussen, A; Perry, A; Wood, M, 2018)
"Human head and neck cancer cells AMC-HN3 were treated with cisplatin- and ALA-mediated PDT individually, and also in combination."1.40Cisplatin enhances the efficacy of 5-aminolevulinic acid mediated photodynamic therapy in human head and neck squamous cell carcinoma. ( Ahn, JC; Biswas, R; Chung, PS; Lee, YK; Mondal, A, 2014)
"(R)L-sulforaphane (SF) is a compound that protects against erythema, but it can also induce DNA fragmentation that leads to cell death by apoptosis."1.35Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy. ( Juzeniene, A; Mikolajewska, P; Moan, J, 2008)
"Etretinate-pretreated cells underwent apoptosis in response to ALA-based PDT."1.35Etretinate enhances the susceptibility of human skin squamous cell carcinoma cells to 5-aminolaevulic acid-based photodynamic therapy. ( Akita, Y; Ishida, N; Kuhara, T; Matsumoto, Y; Nakano, A; Takeo, T; Tamada, Y; Watanabe, D; Yamashita, N; Yanagishita, T, 2009)
"Human prostate cancer (DU-145) and squamous carcinoma (A431) cells were used as experimental model."1.35Diamino acid derivatives of PpIX as potential photosensitizers for photodynamic therapy of squamous cell carcinoma and prostate cancer: in vitro studies. ( Glosnicka, R; Graczyk, A; Juzeniene, A; Kwitniewski, M; Ma, LW; Moan, J, 2009)
"Calcitriol pretreatment of the cells elevated their PpIX levels."1.35Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells. ( Cicarma, E; Juzeniene, A; Ma, LW; Moan, J; Tuorkey, M, 2009)
"The prognosis of patients with oral cancer can be improved by early diagnosis."1.33Topical application of photofrin for photodynamic diagnosis of oral neoplasms. ( Chang, CJ; Wilder-Smith, P, 2005)
"It will be the aim of further investigations to verify the optimal time of incubation and dosing of systemical 5-ALA application to enhance fluorescence contrasts and set the basis for fluorescence guided resections."1.31[Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid]. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Leunig, A, 2002)
" We have investigated the effect of 5-ALA mediated PDT in combination with gamma-irradiation on the colony forming ability of several human head and neck tumour cell lines."1.31Effect of photodynamic therapy in combination with ionizing radiation on human squamous cell carcinoma cell lines of the head and neck. ( Allman, R; Cowburn, P; Mason, M, 2000)
"24 patients suffering from oral cancer were included in this investigation."1.31Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies. ( Arbogast, S; Baumgartner, R; Betz, C; Grevers, G; Leunig, A; Mehlmann, M; Stepp, H, 2001)
"In mice with squamous cell carcinoma, the in vivo expression of PpIX in the tumors was highest with ALA methyl ester, which was 1."1.31In vitro and in vivo expression of protoporphyrin IX induced by lipophilic 5-aminolevulinic acid derivatives. ( Ishibashi, A; Itoh, Y; Ninomiya, Y; Tajima, S, 2001)
"Protoporphyrin IX fluorescence was detected in the oral mucosa of all patients after local application of 5-ALA."1.29Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity. ( Alwin, G; Baumgartner, R; Feyh, J; Gutmann, R; Leunig, A; Rick, K; Stepp, H, 1996)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (13.04)18.2507
2000's19 (41.30)29.6817
2010's19 (41.30)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
Schary, N1
Novak, B1
Kämper, L1
Yousf, A1
Lübbert, H1
León, D1
Buchegger, K1
Silva, R1
Riquelme, I1
Viscarra, T1
Mora-Lagos, B1
Zanella, L1
Schafer, F1
Kurachi, C1
Roa, JC1
Ili, C1
Brebi, P1
Anand, S2
Rollakanti, KR2
Brankov, N1
Brash, DE1
Hasan, T3
Maytin, EV3
Anayo, L1
Magnussen, A1
Perry, A1
Wood, M1
Curnow, A3
Shi, L1
Buchner, A1
Pohla, H1
Pongratz, T1
Rühm, A1
Zimmermann, W1
Gederaas, OA1
Zhang, L1
Wang, X1
Stepp, H5
Sroka, R1
Larisch, P1
Verwanger, T2
Onder, K1
Krammer, B2
Yamamoto, M1
Fujita, H1
Katase, N1
Inoue, K1
Nagatsuka, H1
Utsumi, K1
Sasaki, J1
Ohuchi, H1
Ahn, JC1
Biswas, R1
Mondal, A1
Lee, YK1
Chung, PS1
Blake, E1
Allen, J1
Xie, H1
Xie, Z1
Mousavi, M1
Bendsoe, N1
Brydegaard, M1
Axelsson, J1
Andersson-Engels, S1
Davis, SC2
Pogue, BW2
Bay, C1
Togsverd-Bo, K1
Lerche, CM1
Haedersdal, M1
de Souza, AL1
Marra, K1
Gunn, J1
Samkoe, KS1
Kanick, SC1
Chapman, MS1
Lima, CA1
Goulart, VP1
Bechara, EJ1
Correa, L1
Zezell, DM1
Mikolajewska, P1
Juzeniene, A4
Moan, J4
Ishida, N1
Watanabe, D1
Akita, Y1
Nakano, A1
Yamashita, N1
Kuhara, T1
Yanagishita, T1
Takeo, T1
Tamada, Y1
Matsumoto, Y1
Kwitniewski, M2
Ma, LW3
Glosnicka, R2
Graczyk, A2
Cicarma, E1
Tuorkey, M1
Jankowski, D1
Jaskiewicz, K1
Dziadziuszko, H1
Peksa, R1
Kunikowska, D1
Kwasny, M1
Kaliszewski, M1
Moon, YH1
Park, JH1
Kim, SA1
Lee, JB1
Ahn, SG1
Yoon, JH1
Liutkeviciūte-Navickiene, J1
Mordas, A1
Simkute, S1
Bloznelyte-Plesniene, L1
Uekusa, M1
Omura, K1
Nakajima, Y1
Hasegawa, S1
Harada, H1
Morita, KI1
Tsuda, H1
Mallia, RJ1
Subhash, N1
Sebastian, P1
Kumar, R1
Thomas, SS1
Mathews, A1
Madhavan, J1
Lee, CY1
Kim, KH1
Kim, YH1
Milla, LN1
Cogno, IS1
Rodríguez, ME1
Sanz-Rodríguez, F1
Zamarrón, A1
Gilaberte, Y1
Carrasco, E1
Rivarola, VA1
Juarranz, A1
Lv, Y1
Fang, M1
Zheng, J1
Yang, B1
Li, H1
Xiuzigao, Z1
Song, W1
Chen, Y1
Cao, W1
Gaál, M1
Kui, R1
Hunyadi, Z1
Kemény, L1
Gyulai, R1
Sanovic, R1
Aberger, F1
Frischauf, AM1
Leunig, A5
Betz, CS3
Heinrich, P1
Janda, P2
Baumgartner, R5
Charoenbanpachon, S1
Krasieva, T1
Ebihara, A1
Osann, K1
Wilder-Smith, P2
Chang, CJ1
Ji, Z1
Yang, G1
Vasovic, V1
Cunderlikova, B1
Suo, Z1
Nesland, JM1
Peng, Q1
Ogasawara, T1
Miyoshi, N1
Sano, K1
Kitagawa, Y1
Yamada, T1
Ogawa, T1
Miyauchi, K1
Kinoshita, H1
Smits, T1
Kleinpenning, MM1
Blokx, WA1
van de Kerkhof, PC1
van Erp, PE1
Gerritsen, MJ1
Pye, A1
Grant, WE1
Hopper, C1
MacRobert, AJ1
Speight, PM1
Bown, SG1
Iinuma, S1
Farshi, SS1
Ortel, B1
van der Veen, N1
de Bruijn, HS1
Berg, RJ1
Star, WM1
Rick, K1
Gutmann, R1
Alwin, G1
Feyh, J1
Lucroy, MD1
Edwards, BF1
Peavy, GM1
Krasieva, TB1
Griffey, SM1
Stiles, JB1
Madewell, BR1
Mehlmann, M2
Arbogast, S3
Grevers, G3
Allman, R1
Cowburn, P1
Mason, M1
Betz, C1
Ninomiya, Y1
Itoh, Y1
Tajima, S1
Ishibashi, A1
Kennedy, JC1
Pottier, RH1
Pross, DC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Photodynamic Therapy for Treatment of Cutaneous Squamous Cell Carcinoma in Situ[NCT03025724]40 participants (Anticipated)Interventional2017-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for protoporphyrin ix and Carcinoma, Epidermoid

ArticleYear
[Fluorescence diagnosis of non-melanoma skin cancer].
    Orvosi hetilap, 2012, Aug-26, Volume: 153, Issue:34

    Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Basal Cell; Carcinoma, Basosquamous; Carcinoma, Squamous

2012

Trials

1 trial available for protoporphyrin ix and Carcinoma, Epidermoid

ArticleYear
Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience.
    Journal of photochemistry and photobiology. B, Biology, 1990, Volume: 6, Issue:1-2

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Keratosis; Ph

1990

Other Studies

44 other studies available for protoporphyrin ix and Carcinoma, Epidermoid

ArticleYear
Identification and pharmacological modification of resistance mechanisms to protoporphyrin-mediated photodynamic therapy in human cutaneous squamous cell carcinoma cell lines.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 39

    Topics: Aminolevulinic Acid; ATP-Binding Cassette Transporters; Carcinoma, Squamous Cell; Cell Line, Tumor;

2022
Epigallocatechin Gallate Enhances MAL-PDT Cytotoxic Effect on PDT-Resistant Skin Cancer Squamous Cells.
    International journal of molecular sciences, 2020, May-08, Volume: 21, Issue:9

    Topics: Aminolevulinic Acid; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Catechin; Cell Death; Cell H

2020
Fluorouracil Enhances Photodynamic Therapy of Squamous Cell Carcinoma via a p53-Independent Mechanism that Increases Protoporphyrin IX levels and Tumor Cell Death.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:6

    Topics: Animals; Biosynthetic Pathways; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Cell Prolife

2017
An experimental investigation of a novel iron chelating protoporphyrin IX prodrug for the enhancement of photodynamic therapy.
    Lasers in surgery and medicine, 2018, Volume: 50, Issue:5

    Topics: Carcinoma, Squamous Cell; Cell Culture Techniques; Epithelial Cells; Fibroblasts; Humans; Iron Chela

2018
Methadone enhances the effectiveness of 5-aminolevulinic acid-based photodynamic therapy for squamous cell carcinoma and glioblastoma in vitro.
    Journal of biophotonics, 2019, Volume: 12, Issue:10

    Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Drug Synergi

2019
In vitro analysis of photosensitizer accumulation for assessment of applicability of fluorescence diagnosis of squamous cell carcinoma of epidermolysis bullosa patients.
    BioMed research international, 2013, Volume: 2013

    Topics: Anthracenes; Carcinoma, Squamous Cell; Cell Line, Tumor; Epidermolysis Bullosa; False Positive React

2013
Improvement of the efficacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma HSC-4.
    Acta medica Okayama, 2013, Volume: 67, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, S

2013
Cisplatin enhances the efficacy of 5-aminolevulinic acid mediated photodynamic therapy in human head and neck squamous cell carcinoma.
    General physiology and biophysics, 2014, Volume: 33, Issue:1

    Topics: Aminolevulinic Acid; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cel

2014
The effects of protoporphyrin IX-induced photodynamic therapy with and without iron chelation on human squamous carcinoma cells cultured under normoxic, hypoxic and hyperoxic conditions.
    Photodiagnosis and photodynamic therapy, 2013, Volume: 10, Issue:4

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Synergism; Humans; Iron Chelating Agents; Oxygen; P

2013
Design and validation of a fiber optic point probe instrument for therapy guidance and monitoring.
    Journal of biomedical optics, 2014, Volume: 19, Issue:7

    Topics: Aminolevulinic Acid; Animals; Calibration; Carcinoma, Squamous Cell; Equipment Design; Fiber Optic T

2014
Noninvasive Optical Imaging of UV-Induced Squamous Cell Carcinoma in Murine Skin: Studies of Early Tumor Development and Vitamin D Enhancement of Protoporphyrin IX Production.
    Photochemistry and photobiology, 2015, Volume: 91, Issue:6

    Topics: Animals; Carcinoma, Squamous Cell; Fluorescence; Gene Expression Regulation, Neoplastic; Mice; Optic

2015
Skin tumor development after UV irradiation and photodynamic therapy is unaffected by short-term pretreatment with 5-fluorouracil, imiquimod and calcipotriol. An experimental hairless mouse study.
    Journal of photochemistry and photobiology. B, Biology, 2016, Volume: 154

    Topics: Aminolevulinic Acid; Aminoquinolines; Animals; Calcitriol; Carcinoma, Squamous Cell; Female; Fluorou

2016
Comparing desferrioxamine and light fractionation enhancement of ALA-PpIX photodynamic therapy in skin cancer.
    British journal of cancer, 2016, 09-27, Volume: 115, Issue:7

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose Fractio

2016
Optimization and therapeutic effects of PDT mediated by ALA and MAL in the treatment of cutaneous malignant lesions: A comparative study.
    Journal of biophotonics, 2016, Volume: 9, Issue:11-12

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Female; Mice; Photochemotherapy; Photosensit

2016
Effect of (R)L-sulforaphane on 5-aminolevulinic acid-mediated photodynamic therapy.
    Translational research : the journal of laboratory and clinical medicine, 2008, Volume: 152, Issue:3

    Topics: Aminolevulinic Acid; Anticarcinogenic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Scree

2008
Etretinate enhances the susceptibility of human skin squamous cell carcinoma cells to 5-aminolaevulic acid-based photodynamic therapy.
    Clinical and experimental dermatology, 2009, Volume: 34, Issue:3

    Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Squamous Cell; Cell Death; Dose-Response Relationship, Dr

2009
Diamino acid derivatives of PpIX as potential photosensitizers for photodynamic therapy of squamous cell carcinoma and prostate cancer: in vitro studies.
    Journal of photochemistry and photobiology. B, Biology, 2009, Mar-03, Volume: 94, Issue:3

    Topics: Amino Acids, Diamino; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Screening Assays, Antitumor;

2009
Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells.
    The British journal of dermatology, 2009, Volume: 161, Issue:2

    Topics: Aminolevulinic Acid; Calcitriol; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Line, Tumor;

2009
Photodynamic therapy with 5-aminolevulinic acid and diamino acid derivatives of protoporphyrin IX reduces papillomas in mice without eliminating transformation into squamous cell carcinoma of the skin.
    International journal of cancer, 2009, Oct-01, Volume: 125, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Carcinogens; Carcinoma, Squamous Cel

2009
Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma.
    Head & neck, 2010, Volume: 32, Issue:9

    Topics: Aminolevulinic Acid; Blotting, Western; Carcinoma, Squamous Cell; Caspase 3; Cell Death; Cell Surviv

2010
[Fluorescence diagnostics of skin tumors using 5-aminolevulinic acid and its methyl ester].
    Medicina (Kaunas, Lithuania), 2009, Volume: 45, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell

2009
Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.
    International journal of oral and maxillofacial surgery, 2010, Volume: 39, Issue:8

    Topics: Amino Acids, Neutral; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Deferoxamine; Drug Co

2010
In vivo temporal evolution of ALA-induced normalized fluorescence at different anatomical locations of oral cavity: application to improve cancer diagnostic contrast and potential.
    Photodiagnosis and photodynamic therapy, 2010, Volume: 7, Issue:3

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Squamous Cell; Diagnosis, Oral; Humans; Mou

2010
The efficacy of photodynamic diagnosis in defining the lateral border between a tumor and a tumor-free area during Mohs micrographic surgery.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2010, Volume: 36, Issue:11

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carci

2010
Isolation and characterization of squamous carcinoma cells resistant to photodynamic therapy.
    Journal of cellular biochemistry, 2011, Volume: 112, Issue:9

    Topics: Aminolevulinic Acid; beta Catenin; Cadherins; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Cel

2011
Low-intensity ultrasound combined with 5-aminolevulinic acid administration in the treatment of human tongue squamous carcinoma.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 30, Issue:2

    Topics: Aminolevulinic Acid; Animals; Apoptosis; bcl-2-Associated X Protein; Calcium; Carcinoma, Squamous Ce

2012
Gene expression pattern following photodynamic treatment of the carcinoma cell line A-431 analysed by cDNA arrays.
    International journal of oncology, 2002, Volume: 21, Issue:6

    Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Squamous Cell; Cell Survival; Enzyme Induction; Gene Expr

2002
[Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid].
    Laryngo- rhino- otologie, 2002, Volume: 81, Issue:11

    Topics: Administration, Inhalation; Administration, Oral; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous C

2002
Acceleration of ALA-induced PpIX fluorescence development in the oral mucosa.
    Lasers in surgery and medicine, 2003, Volume: 32, Issue:3

    Topics: Administration, Topical; Aminolevulinic Acid; Analysis of Variance; Animals; Carcinoma, Squamous Cel

2003
Topical application of photofrin for photodynamic diagnosis of oral neoplasms.
    Plastic and reconstructive surgery, 2005, Volume: 115, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cheek; Dihematoporphyrin Ether; Female; Fl

2005
Subcellular localization pattern of protoporphyrin IX is an important determinant for its photodynamic efficiency of human carcinoma and normal cell lines.
    Journal of photochemistry and photobiology. B, Biology, 2006, Sep-01, Volume: 84, Issue:3

    Topics: Adenosine Triphosphate; Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor;

2006
Influence of administration methods on the accumulation of ALA-induced Pp-IX in mouse tongue tumors.
    Oral diseases, 2006, Volume: 12, Issue:4

    Topics: Administration, Oral; Administration, Topical; Aminolevulinic Acid; Animals; Carcinoma, Squamous Cel

2006
Fluorescence diagnosis in keratinocytic intraepidermal neoplasias.
    Journal of the American Academy of Dermatology, 2007, Volume: 57, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Proliferation; D

2007
Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2007, Volume: 26, Issue:2

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Line, Tumor; Deferoxamine; Dose-Response Relatio

2007
Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid.
    Lancet (London, England), 1993, Jul-17, Volume: 342, Issue:8864

    Topics: Administration, Oral; Aminolevulinic Acid; Carcinoma, Squamous Cell; Fluorescence; Humans; Laser The

1993
A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin.
    British journal of cancer, 1994, Volume: 70, Issue:1

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Division;

1994
Kinetics and localisation of PpIX fluorescence after topical and systemic ALA application, observed in skin and skin tumours of UVB-treated mice.
    British journal of cancer, 1996, Volume: 73, Issue:7

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Female; Injections,

1996
Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity.
    American journal of surgery, 1996, Volume: 172, Issue:6

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Squamous Cell; Endoscopy; Humans; Middle Ag

1996
Preclinical study in cats of the pro-photosensitizer 5-aminolevulinic acid.
    American journal of veterinary research, 1999, Volume: 60, Issue:11

    Topics: Aminolevulinic Acid; Animals; Biotransformation; Carcinoma, Squamous Cell; Cat Diseases; Cats; Cell

1999
Detection of squamous cell carcinoma of the oral cavity by imaging 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
    The Laryngoscope, 2000, Volume: 110, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Humans; Middle Aged; Mouth; Mout

2000
Effect of photodynamic therapy in combination with ionizing radiation on human squamous cell carcinoma cell lines of the head and neck.
    British journal of cancer, 2000, Volume: 83, Issue:5

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Combined Modality Therapy;

2000
Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies.
    Journal of photochemistry and photobiology. B, Biology, 2001, Volume: 60, Issue:1

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fluorescence; Humans; Microscopy,

2001
In vitro and in vivo expression of protoporphyrin IX induced by lipophilic 5-aminolevulinic acid derivatives.
    Journal of dermatological science, 2001, Volume: 27, Issue:2

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cells, Cultured; HeLa Cells; Humans; Keratin

2001
A comparative study of normal inspection, autofluorescence and 5-ALA-induced PPIX fluorescence for oral cancer diagnosis.
    International journal of cancer, 2002, Jan-10, Volume: 97, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Female; Fluor

2002