protoporphyrin ix has been researched along with Carcinoma, Basal Cell, Pigmented in 35 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Excerpt | Relevance | Reference |
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"In superficial basal cell carcinomas treated with photodynamic therapy with topical delta-aminolevulinic acid, we examined effects of light irradiance on photodynamic efficiency and pain." | 7.74 | Irradiance-dependent photobleaching and pain in delta-aminolevulinic acid-photodynamic therapy of superficial basal cell carcinomas. ( Cottrell, WJ; Foster, TH; Keymel, KR; Oseroff, AR; Paquette, AD, 2008) |
"In superficial basal cell carcinomas treated with photodynamic therapy with topical delta-aminolevulinic acid, we examined effects of light irradiance on photodynamic efficiency and pain." | 3.74 | Irradiance-dependent photobleaching and pain in delta-aminolevulinic acid-photodynamic therapy of superficial basal cell carcinomas. ( Cottrell, WJ; Foster, TH; Keymel, KR; Oseroff, AR; Paquette, AD, 2008) |
" This method of enhancement was safely applied to a clinical PDT protocol with no unexpected adverse effects reported." | 2.73 | Enhancement of methyl-aminolevulinate photodynamic therapy by iron chelation with CP94: an in vitro investigation and clinical dose-escalating safety study for the treatment of nodular basal cell carcinoma. ( Campbell, S; Curnow, A; Pye, A, 2008) |
"Of the 60 patients (20 Bowen's disease, 20 SCC, and 20 BCC), malignant neoplasms could be clearly distinguished from adjacent healthy tissue under fluorescence illumination (P < 0." | 1.48 | Topical application of Photofrin ( Chang, CJ; Chiang, YF; Hsiao, YC; Lin, YT, 2018) |
" However, in the case of deep, nodular-ulcerative lesions, the complete response rates are lower, possibly related to a lower bioavailability of PpIX." | 1.35 | Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma. ( Ballini, JP; Dögnitz, N; Gabrecht, T; Lange, N; Salomon, D; van den Bergh, H; Wagnières, G; Zellweger, M, 2008) |
"Calcitriol pretreatment of the cells elevated their PpIX levels." | 1.35 | Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells. ( Cicarma, E; Juzeniene, A; Ma, LW; Moan, J; Tuorkey, M, 2009) |
"Ten basal cell carcinomas were coated with an ointment containing 10% ALA prior to excision; five served as controls." | 1.29 | Penetration potency of topical applied delta-aminolevulinic acid for photodynamic therapy of basal cell carcinoma. ( Landthaler, M; Sassy, T; Szeimies, RM, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 8 (22.86) | 18.2507 |
2000's | 14 (40.00) | 29.6817 |
2010's | 12 (34.29) | 24.3611 |
2020's | 1 (2.86) | 2.80 |
Authors | Studies |
---|---|
Stringasci, MD | 1 |
Salvio, AG | 1 |
Moriyama, LT | 1 |
Vollet-Filho, JD | 1 |
Fortunato, TC | 1 |
Bagnato, VS | 1 |
Kurachi, C | 1 |
Lin, YT | 1 |
Hsiao, YC | 1 |
Chiang, YF | 1 |
Chang, CJ | 1 |
Salas-García, I | 2 |
Fanjul-Vélez, F | 2 |
Arce-Diego, JL | 2 |
Salas-García, T | 1 |
López-Gómez, A | 1 |
Dorado-Fernández, M | 1 |
Ruiz-Martínez, J | 1 |
Kulyk, O | 1 |
Ibbotson, SH | 1 |
Moseley, H | 2 |
Valentine, RM | 2 |
Samuel, ID | 1 |
El Hoshy, K | 1 |
Bosseila, M | 1 |
El Sharkawy, D | 1 |
Sobhi, R | 1 |
Cottrell, WJ | 2 |
Paquette, AD | 1 |
Keymel, KR | 1 |
Foster, TH | 2 |
Oseroff, AR | 2 |
Dögnitz, N | 1 |
Salomon, D | 1 |
Zellweger, M | 1 |
Ballini, JP | 1 |
Gabrecht, T | 1 |
Lange, N | 1 |
van den Bergh, H | 1 |
Wagnières, G | 1 |
de Haas, ER | 2 |
de Bruijn, HS | 1 |
Sterenborg, HJ | 2 |
Neumann, HA | 2 |
Robinson, DJ | 2 |
Cicarma, E | 1 |
Tuorkey, M | 1 |
Juzeniene, A | 1 |
Ma, LW | 1 |
Moan, J | 2 |
Wang, KK | 1 |
Mitra, S | 1 |
Liutkeviciūte-Navickiene, J | 1 |
Mordas, A | 1 |
Simkute, S | 1 |
Bloznelyte-Plesniene, L | 1 |
Lee, CY | 1 |
Kim, KH | 1 |
Kim, YH | 1 |
Ortega-Quijano, N | 1 |
Brown, CT | 1 |
Ibbotson, S | 1 |
Wood, K | 1 |
van der Beek, N | 1 |
de Leeuw, J | 1 |
Demmendal, C | 1 |
Bjerring, P | 1 |
Gaál, M | 1 |
Kui, R | 1 |
Hunyadi, Z | 1 |
Kemény, L | 1 |
Gyulai, R | 1 |
Blake, E | 2 |
Allen, J | 2 |
Thorn, C | 1 |
Shore, A | 1 |
Curnow, A | 3 |
Campbell, S | 2 |
Mathew, J | 1 |
Helliwell, P | 1 |
Choudry, K | 1 |
Brooke, RC | 1 |
Farrar, W | 1 |
Rhodes, LE | 1 |
Shen, SC | 1 |
Lee, WR | 1 |
Fang, YP | 1 |
Hu, CH | 1 |
Fang, JY | 1 |
Thompson, MS | 1 |
Andersson-Engels, S | 4 |
Svanberg, S | 4 |
Johansson, T | 1 |
Palsson, S | 1 |
Bendsoe, N | 1 |
Derjabo, A | 1 |
Kapostins, J | 1 |
Stenram, U | 1 |
Spigulis, J | 1 |
Svanberg, K | 4 |
Star, WM | 1 |
van't Veen, AJ | 1 |
Munte, K | 1 |
Won, Y | 1 |
Hong, SH | 1 |
Yu, HY | 1 |
Kwon, YH | 1 |
Yun, SJ | 1 |
Lee, SC | 1 |
Lee, JB | 1 |
Pye, A | 1 |
Roberts, DJ | 1 |
Cairnduff, F | 1 |
Szeimies, RM | 1 |
Sassy, T | 1 |
Landthaler, M | 1 |
Martin, A | 2 |
Tope, WD | 2 |
Grevelink, JM | 1 |
Starr, JC | 1 |
Fewkes, JL | 1 |
Flotte, TJ | 1 |
Deutsch, TF | 1 |
Anderson, RR | 2 |
Heyerdahl, H | 1 |
Wang, I | 3 |
Liu, DL | 1 |
Berg, R | 1 |
Peng, Q | 1 |
Ross, EV | 1 |
Kollias, N | 1 |
Gillies, R | 1 |
Wennberg, AM | 1 |
Gudmundson, F | 1 |
Stenquist, B | 1 |
Ternesten, A | 1 |
Mölne, L | 1 |
Rosén, A | 1 |
Larko, O | 1 |
af Klinteberg, C | 2 |
Enejder, AM | 1 |
Canti, G | 1 |
Cubeddu, R | 1 |
Eker, C | 1 |
Pifferi, A | 1 |
Taroni, P | 1 |
Valentini, G | 1 |
Fischer, F | 1 |
Dickson, EF | 1 |
Kennedy, JC | 2 |
Pottier, RH | 2 |
Pross, DC | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Fluorescence and Thermal Imaging of the Skin Before and During Photodynamic Therapy[NCT03167762] | 18 participants (Actual) | Interventional | 2017-06-22 | Completed | |||
Photodynamic Therapy for Treatment of Cutaneous Squamous Cell Carcinoma in Situ[NCT03025724] | 40 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
3 reviews available for protoporphyrin ix and Carcinoma, Basal Cell, Pigmented
Article | Year |
---|---|
Daylight photodynamic therapy.
Topics: Carcinoma, Basal Cell; Humans; Keratosis, Actinic; Meteorological Concepts; Photochemotherapy; Photo | 2015 |
[Fluorescence diagnosis of non-melanoma skin cancer].
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Basal Cell; Carcinoma, Basosquamous; Carcinoma, Squamous | 2012 |
Photodynamic therapy of primary skin cancer: a review.
Topics: Aged; Aminolevulinic Acid; Antineoplastic Agents; Bowen's Disease; Carcinoma, Basal Cell; Female; Fo | 1995 |
14 trials available for protoporphyrin ix and Carcinoma, Basal Cell, Pigmented
Article | Year |
---|---|
Development of a handheld fluorescence imaging device to investigate the characteristics of protoporphyrin IX fluorescence in healthy and diseased skin.
Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Keratosis, Actinic; Optical Imaging; Photosensit | 2015 |
PpIX fluorescence combined with auto-fluorescence is more accurate than PpIX fluorescence alone in fluorescence detection of non-melanoma skin cancer: an intra-patient direct comparison study.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Bowen's Disease; Carcinoma; Carcinoma, Basal Cell; False Neg | 2012 |
Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Humans; Keratosis, Actinic; Oxygen; Pho | 2013 |
The time-dependent accumulation of protoporphyrin IX fluorescence in nodular basal cell carcinoma following application of methyl aminolevulinate with an oxygen pressure injection device.
Topics: Aminolevulinic Acid; Biological Transport; Carcinoma, Basal Cell; Injections; Oxygen; Photosensitizi | 2012 |
The effect of an iron chelating agent on protoporphyrin IX levels and phototoxicity in topical 5-aminolaevulinic acid photodynamic therapy.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Car | 2003 |
Photodynamic therapy of nodular basal cell carcinoma with multifiber contact light delivery.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Fluorescence; Humans; Lasers; Male; | 2006 |
Topical 5-aminolevulinic acid mediated photodynamic therapy of superficial basal cell carcinoma using two light fractions with a two-hour interval: long-term follow-up.
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Fluorescence; Humans; M | 2006 |
Enhancement of methyl-aminolevulinate photodynamic therapy by iron chelation with CP94: an in vitro investigation and clinical dose-escalating safety study for the treatment of nodular basal cell carcinoma.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Cell Line, Tumor; Humans; In Vi | 2008 |
Lack of selectivity of protoporphyrin IX fluorescence for basal cell carcinoma after topical application of 5-aminolevulinic acid: implications for photodynamic treatment.
Topics: Administration, Cutaneous; Adult; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Humans; Male; | 1995 |
Protoporphyrin IX fluorescence induced in basal cell carcinoma by oral delta-aminolevulinic acid.
Topics: Administration, Oral; Aminolevulinic Acid; Carcinoma, Basal Cell; Drug Interactions; Fluorescence; H | 1998 |
In vivo detection of basal cell carcinoma using imaging spectroscopy.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma, Basal Ce | 1999 |
Kinetic fluorescence studies of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation in basal cell carcinomas.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; | 1999 |
Preliminary evaluation of two fluorescence imaging methods for the detection and the delineation of basal cell carcinomas of the skin.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Male; Photosensi | 2000 |
Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Keratosis; Ph | 1990 |
18 other studies available for protoporphyrin ix and Carcinoma, Basal Cell, Pigmented
Article | Year |
---|---|
Energy analysis of PDT using thermography during the treatment of basal cell carcinoma.
Topics: Aged; Carcinoma, Basal Cell; Female; Humans; Male; Middle Aged; Optical Imaging; Photochemotherapy; | 2020 |
Topical application of Photofrin
Topics: Adult; Aged; Aged, 80 and over; Bowen's Disease; Carcinoma, Basal Cell; Dihematoporphyrin Ether; Fem | 2018 |
Superficial radially resolved fluorescence and 3D photochemical time-dependent model for photodynamic therapy.
Topics: Carcinoma, Basal Cell; Humans; Models, Biological; Photochemical Processes; Photochemotherapy; Photo | 2014 |
Can basal cell carcinoma lateral border be determined by fluorescence diagnosis?: Verification by Mohs micrographic surgery.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Diagnostic Techniques, Surgical; Female; Fl | 2016 |
Irradiance-dependent photobleaching and pain in delta-aminolevulinic acid-photodynamic therapy of superficial basal cell carcinomas.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Huma | 2008 |
Comparison of ALA- and ALA hexyl-ester-induced PpIX depth distribution in human skin carcinoma.
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Dose-Response Relationship, Dru | 2008 |
Microscopic distribution of protoporphyrin (PpIX) fluorescence in superficial basal cell carcinoma during light-fractionated aminolaevulinic acid photodynamic therapy.
Topics: Aminolevulinic Acid; Biopsy; Carcinoma, Basal Cell; Humans; Immunohistochemistry; Ki-67 Antigen; Mic | 2008 |
Calcitriol treatment improves methyl aminolaevulinate-based photodynamic therapy in human squamous cell carcinoma A431 cells.
Topics: Aminolevulinic Acid; Calcitriol; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cell Line, Tumor; | 2009 |
Simulations of measured photobleaching kinetics in human basal cell carcinomas suggest blood flow reductions during ALA-PDT.
Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Models, Cardiovascular; Photobleaching; Photoche | 2009 |
[Fluorescence diagnostics of skin tumors using 5-aminolevulinic acid and its methyl ester].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell | 2009 |
The efficacy of photodynamic diagnosis in defining the lateral border between a tumor and a tumor-free area during Mohs micrographic surgery.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carci | 2010 |
Photodynamic effects on basal cell carcinoma with topical Photosensitizer.
Topics: Administration, Topical; Carcinoma, Basal Cell; Dermatology; Humans; Monte Carlo Method; Necrosis; O | 2010 |
Monte Carlo modeling of in vivo protoporphyrin IX fluorescence and singlet oxygen production during photodynamic therapy for patients presenting with superficial basal cell carcinomas.
Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Models, Biological; Monte Carlo Method; Phantoms | 2011 |
In vitro percutaneous absorption and in vivo protoporphyrin IX accumulation in skin and tumors after topical 5-aminolevulinic acid application with enhancement using an erbium:YAG laser.
Topics: Administration, Cutaneous; Aluminum; Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Cell Line, | 2006 |
Photodetection of basal cell carcinoma using methyl 5-aminolaevulinate-induced protoporphyrin IX based on fluorescence image analysis.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Facial Neoplasms; Female; Humans; Male; Middle Age | 2007 |
Penetration potency of topical applied delta-aminolevulinic acid for photodynamic therapy of basal cell carcinoma.
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Microscopy, Fluorescenc | 1994 |
Pharmacokinetic studies on 5-aminolevulinic acid-induced protoporphyrin IX accumulation in tumours and normal tissues.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Drug Interactions; Humans; Live | 1997 |
An affordable, portable fluorescence imaging device for skin lesion detection using a dual wavelength approach for image contrast enhancement and aminolaevulinic acid-induced protoporphyrin IX. Part II. In vivo testing.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Female; Humans; Mice; Mice, Inbred BALB C; Phot | 2001 |