Page last updated: 2024-11-03

protoporphyrin ix and Cancer of Mouth

protoporphyrin ix has been researched along with Cancer of Mouth in 21 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Research Excerpts

ExcerptRelevanceReference
"Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX was found as a valuable tool in the diagnosis of oral premalignancy."2.72Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. ( El-Maaytah, M; Hopper, C; Jerjes, W; Khalil, HS; MacRobert, AJ; Salih, V; Sharwani, A, 2006)
"The prognosis of patients with oral cancer can be improved by early diagnosis."1.33Topical application of photofrin for photodynamic diagnosis of oral neoplasms. ( Chang, CJ; Wilder-Smith, P, 2005)
"It will be the aim of further investigations to verify the optimal time of incubation and dosing of systemical 5-ALA application to enhance fluorescence contrasts and set the basis for fluorescence guided resections."1.31[Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid]. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Leunig, A, 2002)
"24 patients suffering from oral cancer were included in this investigation."1.31Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies. ( Arbogast, S; Baumgartner, R; Betz, C; Grevers, G; Leunig, A; Mehlmann, M; Stepp, H, 2001)
"Protoporphyrin IX fluorescence was detected in the oral mucosa of all patients after local application of 5-ALA."1.29Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity. ( Alwin, G; Baumgartner, R; Feyh, J; Gutmann, R; Leunig, A; Rick, K; Stepp, H, 1996)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (14.29)18.2507
2000's10 (47.62)29.6817
2010's8 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosin, FCP1
Teixeira, MG1
Pelissari, C1
Corrêa, L1
Sarkar, R1
Chatterjee, K1
Ojha, D1
Chakraborty, B1
Sengupta, S1
Chattopadhyay, D1
RoyChaudhuri, C1
Barui, A1
Yamamoto, M1
Fujita, H1
Katase, N1
Inoue, K1
Nagatsuka, H1
Utsumi, K1
Sasaki, J1
Ohuchi, H1
Yang, SJ1
Lin, CF1
Kuo, ML1
Tan, CT1
Moon, YH1
Park, JH1
Kim, SA1
Lee, JB1
Ahn, SG1
Yoon, JH1
Uekusa, M1
Omura, K1
Nakajima, Y1
Hasegawa, S1
Harada, H1
Morita, KI1
Tsuda, H1
Mallia, RJ1
Subhash, N1
Sebastian, P1
Kumar, R1
Thomas, SS1
Mathews, A1
Madhavan, J1
Jiang, CF1
Wang, CY1
Chiang, CP1
Zheng, W2
Soo, KC2
Sivanandan, R1
Olivo, M2
Leunig, A5
Betz, CS3
Heinrich, P1
Janda, P2
Baumgartner, R5
Charoenbanpachon, S1
Krasieva, T1
Ebihara, A1
Osann, K1
Wilder-Smith, P2
Chang, CJ1
Sharwani, A1
Jerjes, W1
Salih, V1
MacRobert, AJ2
El-Maaytah, M1
Khalil, HS1
Hopper, C2
Sharma, S1
Jajoo, A1
Dube, A1
Grant, WE1
Speight, PM1
Bown, SG1
Rick, K1
Stepp, H4
Gutmann, R1
Alwin, G1
Feyh, J1
Zenk, W1
Dietel, W1
Schleier, P1
Günzel, S1
Mehlmann, M2
Arbogast, S3
Grevers, G3
Betz, C1

Trials

1 trial available for protoporphyrin ix and Cancer of Mouth

ArticleYear
Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy.
    Journal of photochemistry and photobiology. B, Biology, 2006, Apr-03, Volume: 83, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Humans; Middle Aged; Mouth Neoplasms; P

2006

Other Studies

20 other studies available for protoporphyrin ix and Cancer of Mouth

ArticleYear
Resistance of oral cancer cells to 5-ALA-mediated photodynamic therapy.
    Journal of cellular biochemistry, 2018, Volume: 119, Issue:4

    Topics: Aminolevulinic Acid; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Movement; Cell Proliferati

2018
Liaison between heme metabolism and bioenergetics pathways-a multimodal elucidation for early diagnosis of oral cancer.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 21

    Topics: 5-Aminolevulinate Synthetase; Adult; Aged; ATP Binding Cassette Transporter, Subfamily G, Member 2;

2018
Improvement of the efficacy of 5-aminolevulinic acid-mediated photodynamic treatment in human oral squamous cell carcinoma HSC-4.
    Acta medica Okayama, 2013, Volume: 67, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, S

2013
Photodynamic detection of oral cancers with high-performance chitosan-based nanoparticles.
    Biomacromolecules, 2013, Sep-09, Volume: 14, Issue:9

    Topics: Animals; Cell Line, Tumor; Chitosan; Female; Fluoresceins; Fluorescent Dyes; Folic Acid; Folic Acid

2013
Anticancer effect of photodynamic therapy with hexenyl ester of 5-aminolevulinic acid in oral squamous cell carcinoma.
    Head & neck, 2010, Volume: 32, Issue:9

    Topics: Aminolevulinic Acid; Blotting, Western; Carcinoma, Squamous Cell; Caspase 3; Cell Death; Cell Surviv

2010
Uptake and kinetics of 5-aminolevulinic acid in oral squamous cell carcinoma.
    International journal of oral and maxillofacial surgery, 2010, Volume: 39, Issue:8

    Topics: Amino Acids, Neutral; Animals; Carcinoma, Squamous Cell; Cell Differentiation; Deferoxamine; Drug Co

2010
In vivo temporal evolution of ALA-induced normalized fluorescence at different anatomical locations of oral cavity: application to improve cancer diagnostic contrast and potential.
    Photodiagnosis and photodynamic therapy, 2010, Volume: 7, Issue:3

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Squamous Cell; Diagnosis, Oral; Humans; Mou

2010
Comparative study of protoporphyrin IX fluorescence image enhancement methods to improve an optical imaging system for oral cancer detection.
    Journal of biomedical optics, 2011, Volume: 16, Issue:7

    Topics: Aminolevulinic Acid; Diagnostic Imaging; Fluorescence; Humans; Image Enhancement; Mouth Neoplasms; O

2011
Detection of neoplasms in the oral cavity by digitized endoscopic imaging of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
    International journal of oncology, 2002, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Aminolevulinic Acid; Endoscopy; Female; Fluorescent Dyes

2002
[Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid].
    Laryngo- rhino- otologie, 2002, Volume: 81, Issue:11

    Topics: Administration, Inhalation; Administration, Oral; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous C

2002
Acceleration of ALA-induced PpIX fluorescence development in the oral mucosa.
    Lasers in surgery and medicine, 2003, Volume: 32, Issue:3

    Topics: Administration, Topical; Aminolevulinic Acid; Analysis of Variance; Animals; Carcinoma, Squamous Cel

2003
The use of digitized endoscopic imaging of 5-ALA-induced PPIX fluorescence to detect and diagnose oral premalignant and malignant lesions in vivo.
    International journal of cancer, 2004, Jun-10, Volume: 110, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Diagnostic Imaging; Endoscopy; Female; Fluoresc

2004
Topical application of photofrin for photodynamic diagnosis of oral neoplasms.
    Plastic and reconstructive surgery, 2005, Volume: 115, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cheek; Dihematoporphyrin Ether; Female; Fl

2005
5-Aminolevulinic acid-induced protoporphyrin-IX accumulation and associated phototoxicity in macrophages and oral cancer cell lines.
    Journal of photochemistry and photobiology. B, Biology, 2007, Sep-25, Volume: 88, Issue:2-3

    Topics: Aminolevulinic Acid; Animals; Biological Assay; Carcinoma, Transitional Cell; Cell Line, Tumor; Huma

2007
Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid.
    Lancet (London, England), 1993, Jul-17, Volume: 342, Issue:8864

    Topics: Administration, Oral; Aminolevulinic Acid; Carcinoma, Squamous Cell; Fluorescence; Humans; Laser The

1993
Fluorescence imaging and spectroscopy of 5-aminolevulinic acid induced protoporphyrin IX for the detection of neoplastic lesions in the oral cavity.
    American journal of surgery, 1996, Volume: 172, Issue:6

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Squamous Cell; Endoscopy; Humans; Middle Ag

1996
[Visualizing carcinomas of the mouth cavity by stimulating synthesis of fluorescent protoporphyrin IX].
    Mund-, Kiefer- und Gesichtschirurgie : MKG, 1999, Volume: 3, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Female; Humans; Male; Middle Aged; Mout

1999
Detection of squamous cell carcinoma of the oral cavity by imaging 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
    The Laryngoscope, 2000, Volume: 110, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Humans; Middle Aged; Mouth; Mout

2000
Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies.
    Journal of photochemistry and photobiology. B, Biology, 2001, Volume: 60, Issue:1

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fluorescence; Humans; Microscopy,

2001
A comparative study of normal inspection, autofluorescence and 5-ALA-induced PPIX fluorescence for oral cancer diagnosis.
    International journal of cancer, 2002, Jan-10, Volume: 97, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Female; Fluor

2002