Page last updated: 2024-11-03

protoporphyrin ix and Barrett Epithelium

protoporphyrin ix has been researched along with Barrett Epithelium in 23 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Research Excerpts

ExcerptRelevanceReference
"Surveillance of patients with Barrett's esophagus or ulcerative colitis for dysplasia is confined to biopsy specimens taken randomly during endoscopy because dysplasia remains undetectable by visual inspection."5.30Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization. ( Bäumler, W; Holstege, A; Knüchel, R; Messmann, H; Schölmerich, J, 1999)
" The aim of this study was to establish the optimum dosage regime for ALA-PDT for Barrett's esophagus."2.71Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus. ( Ackroyd, R; Brown, NJ; Brown, SB; Kelty, CJ; Reed, MW, 2004)
"Barrett's esophagus has been identified as the premalignant precursor of esophageal adenocarcinoma."2.41Barrett's esophagus: treatment with 5-aminolevulinic acid photodynamic therapy. ( Barr, H, 2000)
"Preliminary studies in early esophageal cancer also show effectiveness."2.41Photodynamic therapy for esophageal cancer. Update. ( Greenwald, BD, 2000)
"Barrett's esophagus is strongly associated with adenocarcinoma."1.32Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid. ( Dorta, G; Felley, C; Fontolliet, C; Gabrecht, T; Grosjean, P; Jornod, P; Lange, N; Monnier, P; Stepinac, T; van den Bergh, H; vanMelle, G; Wagnières, G, 2003)
"Surveillance of patients with Barrett's esophagus or ulcerative colitis for dysplasia is confined to biopsy specimens taken randomly during endoscopy because dysplasia remains undetectable by visual inspection."1.30Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization. ( Bäumler, W; Holstege, A; Knüchel, R; Messmann, H; Schölmerich, J, 1999)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (30.43)18.2507
2000's13 (56.52)29.6817
2010's3 (13.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yeh, SC2
Ling, CS1
Andrews, DW2
Patterson, MS2
Diamond, KR1
Hayward, JE1
Armstrong, D2
Fang, Q2
Sahli, S1
Provias, J1
Holz, JA1
Boerwinkel, DF1
Meijer, SL1
Visser, M1
van Leeuwen, TG1
Bergman, JJ1
Aalders, MC1
Hinnen, P4
de Rooij, FW4
Hop, WC1
Edixhoven, A4
van Dekken, H2
Wilson, JH4
Siersema, PD5
Brand, S1
Wang, TD1
Schomacker, KT1
Poneros, JM1
Lauwers, GY1
Compton, CC1
Pedrosa, MC1
Nishioka, NS1
Ortner, MA1
Ebert, B1
Hein, E1
Zumbusch, K1
Nolte, D1
Sukowski, U1
Weber-Eibel, J1
Fleige, B1
Dietel, M1
Stolte, M1
Oberhuber, G1
Porschen, R1
Klump, B1
Hörtnagl, H1
Lochs, H2
Rinneberg, H1
Stepinac, T1
Felley, C1
Jornod, P1
Lange, N1
Gabrecht, T1
Fontolliet, C1
Grosjean, P1
vanMelle, G1
van den Bergh, H1
Monnier, P1
Wagnières, G1
Dorta, G1
Kelty, CJ1
Ackroyd, R2
Brown, NJ1
Brown, SB1
Reed, MW1
Barr, H2
Shepherd, NA1
Dix, A1
Roberts, DJ1
Tan, WC1
Krasner, N1
Vonarx, V1
Eleouet, S1
Carre, J1
Ioss, P1
Gouyette, A1
Leray, AM1
Merle, C1
Lajat, Y2
Patrice, T2
Ortner, M1
Messmann, H2
Knüchel, R2
Endlicher, E1
Hauser, T1
Szeimies, RM1
Kullmann, F1
Bäumler, W2
Schölmerich, J2
van Velthuysen, ML1
van Hillegersberg, R3
Tilanus, HW2
Holstege, A1
Brown, N1
Vernon, D1
Roberts, D1
Stephenson, T1
Marcus, S1
Stoddard, C1
Reed, M1
Wang, KK1
Terlouw, EM1
Greenwald, BD1
van den Boogert, J1
van Staveren, HJ1
de Bruin, RW1
Bourre, L1
Thibaut, S1
Briffaud, A1
Pech, O1
Nagy, CD1
Gossner, L1
May, A1
Ell, C1

Reviews

3 reviews available for protoporphyrin ix and Barrett Epithelium

ArticleYear
Barrett's esophagus: treatment with 5-aminolevulinic acid photodynamic therapy.
    Gastrointestinal endoscopy clinics of North America, 2000, Volume: 10, Issue:3

    Topics: Aminolevulinic Acid; Barrett Esophagus; Esophagoscopy; Humans; Injections, Intravenous; Intestinal M

2000
Photodynamic therapy of Barrett's esophagus.
    Gastrointestinal endoscopy clinics of North America, 2000, Volume: 10, Issue:3

    Topics: Aminolevulinic Acid; Barrett Esophagus; Esophagoscopy; Fiber Optic Technology; Hematoporphyrin Deriv

2000
Photodynamic therapy for esophageal cancer. Update.
    Chest surgery clinics of North America, 2000, Volume: 10, Issue:3

    Topics: Animals; Barrett Esophagus; Dihematoporphyrin Ether; Esophageal Neoplasms; Humans; Photochemotherapy

2000

Trials

3 trials available for protoporphyrin ix and Barrett Epithelium

ArticleYear
Timing of 5-aminolaevulinic acid-induced photodynamic therapy for the treatment of patients with Barrett's oesophagus.
    Journal of photochemistry and photobiology. B, Biology, 2002, Volume: 68, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Endoscopy; Female

2002
Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus.
    Surgical endoscopy, 2004, Volume: 18, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Cohort

2004
5-Aminolevulinic acid photosensitization of dysplastic Barrett's esophagus: a pharmacokinetic study.
    Photochemistry and photobiology, 1999, Volume: 70, Issue:4

    Topics: Aminolevulinic Acid; Barrett Esophagus; Humans; Photochemotherapy; Photosensitizing Agents; Protopor

1999

Other Studies

17 other studies available for protoporphyrin ix and Barrett Epithelium

ArticleYear
5-aminolevulinic acid for quantitative seek-and-treat of high-grade dysplasia in Barrett's esophagus cellular models.
    Journal of biomedical optics, 2015, Volume: 20, Issue:2

    Topics: Aminolevulinic Acid; Barrett Esophagus; Cell Line, Tumor; Cell Survival; Humans; Intracellular Space

2015
5-Aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett's esophagus cellular models.
    Journal of biomedical optics, 2015, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Algorithms; Aminolevulinic Acid; Barrett Esophagus; Biomarkers; Esophageal Neoplasms

2015
Fluorescence characteristics of human Barrett tissue specimens grafted on chick chorioallantoic membrane.
    Lasers in medical science, 2016, Volume: 31, Issue:1

    Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Biopsy; Chickens; Chorioallantoic Membrane; Humans;

2016
Detection of high-grade dysplasia in Barrett's esophagus by spectroscopy measurement of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
    Gastrointestinal endoscopy, 2002, Volume: 56, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esopha

2002
Time gated fluorescence spectroscopy in Barrett's oesophagus.
    Gut, 2003, Volume: 52, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Biomarkers,

2003
Two course illuminating scheme improves aminolevulinic acid photodynamic therapy in cell cultures.
    Cellular and molecular biology (Noisy-le-Grand, France), 2002, Volume: 48, Issue:8

    Topics: Aminolevulinic Acid; Barrett Esophagus; Cell Line, Transformed; Cells, Cultured; Ferrochelatase; Hum

2002
Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid.
    Endoscopy, 2003, Volume: 35, Issue:8

    Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Carcinoma in Situ; Esopha

2003
Eradication of high-grade dysplasia in columnar-lined (Barrett's) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX.
    Lancet (London, England), 1996, Aug-31, Volume: 348, Issue:9027

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Humans; Male; Middle Aged; Photoche

1996
Potential efficacy of a delta 5-aminolevulinic acid bioadhesive gel formulation for the photodynamic treatment of lesions of the gastrointestinal tract in mice.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:7

    Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Biocompatible Materials; Disease Models, Animal; Fi

1997
[Eradication of high-grade dysplasia in Barrett esophagus by photodynamic therapy with endogenously generated protoporphyrin IX].
    Zeitschrift fur Gastroenterologie, 1998, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Fe

1998
[Photodynamic diagnosis of gastrointestinal precancerous lesions after sensitization with 5-aminolevulinic acid. A pilot study].
    Deutsche medizinische Wochenschrift (1946), 1998, Apr-24, Volume: 123, Issue:17

    Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colorectal Neopla

1998
Biochemical basis of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation: a study in patients with (pre)malignant lesions of the oesophagus.
    British journal of cancer, 1998, Volume: 78, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Female; Ferroc

1998
Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization.
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:1

    Topics: Adenomatous Polyps; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Colitis, Ulcerative

1999
Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid.
    British journal of cancer, 2000, Volume: 83, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett E

2000
Fractionated illumination for oesophageal ALA-PDT: effect on blood flow and PpIX formation.
    Lasers in medical science, 2001, Volume: 16, Issue:1

    Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Esophagus; Male; Photochemotherapy; Protoporphyrins

2001
Potential efficacy of a delta 5-aminolevulinic acid thermosetting gel formulation for use in photodynamic therapy of lesions of the gastrointestinal tract.
    Pharmacological research, 2002, Volume: 45, Issue:2

    Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Drug Stability; Gastric Mucosa; Gels; Male; Mice; M

2002
Photodynamic therapy of human Barrett's cancer using 5-aminolaevulinic acid-induced protoporphyrin IX: an in-vivo dosimetry study in athymic nude mice.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:6

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Barrett Esophagus; Esophageal Neoplasms; Humans; Mice;

2002