Page last updated: 2024-11-03

protoporphyrin ix and Adenocarcinoma

protoporphyrin ix has been researched along with Adenocarcinoma in 32 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" This research aimed to assess the cytogenetic potential of 5-aminolevulinic acid (5-ALA) activated with laser irradiation (5-ALA/PDT) to damage the intact DNA of adenocarcinoma breast cancer cell line (MCF-7) and hepatocellular carcinoma cell line (HepG2)."7.88Photodynamic therapy using 5-aminolevulinic acid triggered DNA damage of adenocarcinoma breast cancer and hepatocellular carcinoma cell lines. ( Abo-Elfadl, MT; Abo-Zeid, MAM; Mostafa, SM, 2018)
"5-aminolevulinic acid heptyl ester was investigated in human adenocarcinoma WiDr cells and in healthy skin of athymic nude mice in comparison with 5-aminolevulinic acid (ALA)."7.75A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin. ( Iani, V; Juzeniene, A; Ma, LW; Moan, J; Pudroma, X, 2009)
"BALB/c nude mice bearing WiDr human colon adenocarcinoma were used to determine the effect of ultrasound on the production of 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) both in the tumors and in skin overlying the tumors."7.70Production of protoporphyrin IX induced by 5-aminolevulinic acid in transplanted human colon adenocarcinoma of nude mice can be increased by ultrasound. ( Iani, V; Ma, L; Moan, J; Peng, Q, 1998)
" This research aimed to assess the cytogenetic potential of 5-aminolevulinic acid (5-ALA) activated with laser irradiation (5-ALA/PDT) to damage the intact DNA of adenocarcinoma breast cancer cell line (MCF-7) and hepatocellular carcinoma cell line (HepG2)."3.88Photodynamic therapy using 5-aminolevulinic acid triggered DNA damage of adenocarcinoma breast cancer and hepatocellular carcinoma cell lines. ( Abo-Elfadl, MT; Abo-Zeid, MAM; Mostafa, SM, 2018)
"5-aminolevulinic acid heptyl ester was investigated in human adenocarcinoma WiDr cells and in healthy skin of athymic nude mice in comparison with 5-aminolevulinic acid (ALA)."3.75A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin. ( Iani, V; Juzeniene, A; Ma, LW; Moan, J; Pudroma, X, 2009)
" It is shown that sublethal PDT of human WiDr adenocarcinoma cells and D54Mg glioblastoma cells with 5-aminolevulinic acid (ALA), disulfonated tetraphenylporphyrine (TPPS(2a)), or MitoTracker Red (MTR) inhibits their trypsin-induced detachment from a plastic substratum."3.72Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum. ( Juzeniene, A; Ma, LW; Moan, J; Uzdensky, A, 2004)
"Human adenocarcinoma cells of the line WiDr and human leukemia T cells of the line Jurkat were incubated with 5-aminolevulinic acid and found to produce protoporphyrin IX (PpIX)."3.71Transfer of protoporphyrin IX between cells. ( Ma, LW; Moan, J; Stokke, T, 2002)
"The photodynamic effect of a photoproduct of protoporphyrin IX (PpIX) induced by 5-aminolevulinic acid (ALA) was investigated in WiDr cells, a human adenocarcinoma cell line."3.71The photosensitizing effect of the photoproduct of protoporphyrin IX. ( Bagdonas, S; Ma, L; Moan, J, 2001)
"Human colon adenocarcinoma cells (WiDr) and Chinese hamster lung fibroblasts cells (V79) were incubated with different concentrations of 5-aminolevulinic acid (ALA), and the production of protoporphyrin IX (PpIX) was studied using several techniques."3.70Protoporphyrin IX accumulation in cells treated with 5-aminolevulinic acid: dependence on cell density, cell size and cell cycle. ( Bech, O; Berg, K; Gaullier, JM; Ma, LW; Moan, J; Steen, HB; Stokke, T, 1998)
"BALB/c nude mice bearing WiDr human colon adenocarcinoma were used to determine the effect of ultrasound on the production of 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) both in the tumors and in skin overlying the tumors."3.70Production of protoporphyrin IX induced by 5-aminolevulinic acid in transplanted human colon adenocarcinoma of nude mice can be increased by ultrasound. ( Iani, V; Ma, L; Moan, J; Peng, Q, 1998)
"The response of human colon adenocarcinoma cells of the line WiDr to the combined treatment of ionizing radiation and photosensitization by 5-aminolevulinic acid-induced protoporphyrin IX was assessed by a colony-forming assay."3.69Combined treatment of ionizing radiation and photosensitization by 5-aminolevulinic acid-induced protoporphyrin IX. ( Berg, K; Luksiene, Z; Ma, L; Moan, J, 1995)
"Chinese hamster cells (V79) and human adenocarcinoma cells (WiDr) were incubated with 5-aminolevulinic acid (ALA) at different pH values and the rate of production of protoporphyrin IX (PpIX) was measured."3.69The pH dependency of protoporphyrin IX formation in cells incubated with 5-aminolevulinic acid. ( Bech, O; Berg, K; Moan, J, 1997)
"Human tumor cells of the lines WiDr (adenocarcinoma of the rectosigmoid colon), NHIK 3025 (carcinoma of the cervix), and V79 Chinese hamster fibroblasts were treated with 5-aminolevulinic acid (ALA) and ALA esterified to C1-C3 and C6-C8 chained aliphatic alcohols (ALA-esters)."3.69Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture. ( Anholt, H; Berg, K; Gaullier, JM; Ma, LW; Moan, J; Peng, Q; Selbo, PK, 1997)
"5-aminolevulinic acid (5-ALA) has been utilized for cancer diagnosis as a fluorescence probe."1.565-ALA-assistant automated detection of lymph node metastasis in gastric cancer patients. ( Harada, Y; Koshiishi, N; Matsumoto, T; Matsuo, H; Murayama, Y; Okochi, K; Otsuji, E; Takamatsu, T; Tanaka, H, 2020)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (37.50)18.2507
2000's14 (43.75)29.6817
2010's5 (15.63)24.3611
2020's1 (3.13)2.80

Authors

AuthorsStudies
Matsumoto, T1
Murayama, Y2
Matsuo, H1
Okochi, K1
Koshiishi, N1
Harada, Y2
Tanaka, H2
Takamatsu, T2
Otsuji, E2
Abo-Zeid, MAM1
Abo-Elfadl, MT1
Mostafa, SM1
Lualdi, M1
Cavalleri, A1
Battaglia, L1
Colombo, A1
Garrone, G1
Morelli, D1
Pignoli, E1
Sottotetti, E1
Leo, E1
Yeh, SC1
Sahli, S1
Andrews, DW1
Patterson, MS1
Armstrong, D1
Provias, J1
Fang, Q1
Koizumi, N1
Beika, M1
Minamikawa, T1
Yamaoka, Y1
Dai, P1
Yanagisawa, A1
Ascencio, M1
Collinet, P1
Farine, MO1
Mordon, S1
Casas, A1
Battah, S1
Di Venosa, G1
Dobbin, P1
Rodriguez, L1
Fukuda, H2
Batlle, A2
MacRobert, AJ1
Pudroma, X1
Moan, J12
Ma, LW6
Iani, V3
Juzeniene, A2
Ziegler, VG1
Knaup, J1
Stahl, D1
Krammer, B1
Plaetzer, K1
Krieg, RC3
Messmann, H3
Rauch, J1
Seeger, S2
Knuechel, R3
Stokke, T3
Ortner, MA1
Ebert, B1
Hein, E1
Zumbusch, K1
Nolte, D1
Sukowski, U1
Weber-Eibel, J1
Fleige, B1
Dietel, M1
Stolte, M1
Oberhuber, G1
Porschen, R1
Klump, B1
Hörtnagl, H1
Lochs, H1
Rinneberg, H1
Schlottmann, K1
Endlicher, E2
Schölmerich, J2
Uzdensky, A1
Alvarez, MG1
Lacelli, MS1
Rivarola, V1
Berg, K6
Luksiene, Z1
Ma, L3
Fromm, D2
Kessel, D2
Webber, J2
Noodt, BB1
Peng, Q4
Nesland, JM1
Wyss-Desserich, MT1
Sun, CH1
Wyss, P1
Kurlawalla, CS1
Haller, U1
Berns, MW1
Tadir, Y1
Anholt, H2
Bech, O3
Gederaas, OA1
Thorstensen, K1
Romslo, I1
Heyerdahl, H1
Wang, I1
Liu, DL1
Berg, R1
Andersson-Engels, S1
Svanberg, S1
Svanberg, K1
Gaullier, JM2
Selbo, PK1
Steen, HB1
Hinnen, P1
de Rooij, FW1
Terlouw, EM1
Edixhoven, A1
van Dekken, H1
van Hillegersberg, R1
Tilanus, HW1
Wilson, JH1
Siersema, PD1
Bagdonas, S1
Brunner, H1
Hausmann, F1
Pech, O1
Nagy, CD1
Gossner, L1
May, A1
Ell, C1

Trials

1 trial available for protoporphyrin ix and Adenocarcinoma

ArticleYear
Side effects and photosensitization of human tissues after aminolevulinic acid.
    The Journal of surgical research, 1997, Feb-15, Volume: 68, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Aminolevulinic Acid; Female; Gastrointestinal Neoplasms; Human

1997

Other Studies

31 other studies available for protoporphyrin ix and Adenocarcinoma

ArticleYear
5-ALA-assistant automated detection of lymph node metastasis in gastric cancer patients.
    Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2020, Volume: 23, Issue:4

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Fluorescent Dyes; Follo

2020
Photodynamic therapy using 5-aminolevulinic acid triggered DNA damage of adenocarcinoma breast cancer and hepatocellular carcinoma cell lines.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 21

    Topics: Adenocarcinoma; Aminolevulinic Acid; Breast Neoplasms; Carcinoma, Hepatocellular; DNA Damage; Hep G2

2018
Early detection of colorectal adenocarcinoma: a clinical decision support tool based on plasma porphyrin accumulation and risk factors.
    BMC cancer, 2018, Aug-22, Volume: 18, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Coproporphyrins; Early Diagnos

2018
5-Aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett's esophagus cellular models.
    Journal of biomedical optics, 2015, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Algorithms; Aminolevulinic Acid; Barrett Esophagus; Biomarkers; Esophageal Neoplasms

2015
Highly sensitive fluorescence detection of metastatic lymph nodes of gastric cancer with photo-oxidation of protoporphyrin IX.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2016, Volume: 42, Issue:8

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cell Line, Tumor; Female; Human

2016
Protoporphyrin IX fluorescence photobleaching is a useful tool to predict the response of rat ovarian cancer following hexaminolevulinate photodynamic therapy.
    Lasers in surgery and medicine, 2008, Volume: 40, Issue:5

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Female; Microscopy, Fluorescence; Ovarian Neoplasms; P

2008
Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, Apr-17, Volume: 135, Issue:2

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Coloring Agents; Dend

2009
A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin.
    Experimental dermatology, 2009, Volume: 18, Issue:11

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Line, Tumor; Drug Screening Assays, Antitumor; Hu

2009
Fluorescence detection and depletion of T47D breast cancer cells from human mononuclear cell-enriched blood preparations by photodynamic treatment: Basic in vitro experiments towards the removal of circulating tumor cells.
    Lasers in surgery and medicine, 2011, Volume: 43, Issue:7

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Breast Neoplasms; Cell Line; Cell Line, Tumor; Endothe

2011
Metabolic characterization of tumor cell-specific protoporphyrin IX accumulation after exposure to 5-aminolevulinic acid in human colonic cells.
    Photochemistry and photobiology, 2002, Volume: 76, Issue:5

    Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship

2002
Transfer of protoporphyrin IX between cells.
    Photochemistry and photobiology, 2002, Volume: 76, Issue:5

    Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Communication; Cell Line, Tumor; Colonic Neoplasms; Humans

2002
Time gated fluorescence spectroscopy in Barrett's oesophagus.
    Gut, 2003, Volume: 52, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Biomarkers,

2003
Intracellular localization is a cofactor for the phototoxicity of protoporphyrin IX in the gastrointestinal tract: in vitro study.
    Photochemistry and photobiology, 2003, Volume: 78, Issue:4

    Topics: Adenocarcinoma; Colonic Neoplasms; Digestive System; Humans; Photochemotherapy; Photosensitizing Age

2003
Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum.
    Biochimica et biophysica acta, 2004, Jan-05, Volume: 1670, Issue:1

    Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Cell Survival;

2004
5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2007, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Aminolevulinic Acid; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; D

2007
Combined treatment of ionizing radiation and photosensitization by 5-aminolevulinic acid-induced protoporphyrin IX.
    Radiation research, 1995, Volume: 142, Issue:3

    Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Cycle; Cell Division; Cell Line; Cell Survival; Colonic Ne

1995
Feasibility of photodynamic therapy using endogenous photosensitization for colon cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1996, Volume: 131, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Aminolevulinic Acid; Biopsy; Colectomy; Colon, Sigmoid; Follow

1996
Apoptosis and necrosis induced with light and 5-aminolaevulinic acid-derived protoporphyrin IX.
    British journal of cancer, 1996, Volume: 74, Issue:1

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Apoptosis; Cells, Cultured; Colonic Neoplasms; Criceti

1996
Accumulation of 5-aminolevulinic acid-induced protoporphyrin IX in normal and neoplastic human endometrial epithelial cells.
    Biochemical and biophysical research communications, 1996, Jul-25, Volume: 224, Issue:3

    Topics: Adenocarcinoma; Aminolevulinic Acid; Cells, Cultured; Endometrial Neoplasms; Endometrium; Epithelial

1996
The influence of iron chelators on the accumulation of protoporphyrin IX in 5-aminolaevulinic acid-treated cells.
    British journal of cancer, 1996, Volume: 74, Issue:5

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Colonic Neoplasms; Cricetinae; Cricetulus; Dicarbethox

1996
The effect of brief illumination on intracellular free calcium concentration in cells with 5-aminolevulinic acid-induced protoporphyrin IX synthesis.
    Scandinavian journal of clinical and laboratory investigation, 1996, Volume: 56, Issue:7

    Topics: Adenocarcinoma; Aminolevulinic Acid; Calcium; Colonic Neoplasms; Cytosol; DNA; Egtazic Acid; Fluores

1996
The pH dependency of protoporphyrin IX formation in cells incubated with 5-aminolevulinic acid.
    Cancer letters, 1997, Feb-26, Volume: 113, Issue:1-2

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Survival; Colonic Neoplasms; Cricetinae; Fibrobla

1997
Pharmacokinetic studies on 5-aminolevulinic acid-induced protoporphyrin IX accumulation in tumours and normal tissues.
    Cancer letters, 1997, Jan-30, Volume: 112, Issue:2

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Drug Interactions; Humans; Live

1997
Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture.
    Cancer research, 1997, Apr-15, Volume: 57, Issue:8

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Colonic Neoplasms; Cricetinae; Cricetulus; Drug Screen

1997
Protoporphyrin IX accumulation in cells treated with 5-aminolevulinic acid: dependence on cell density, cell size and cell cycle.
    International journal of cancer, 1998, Jan-05, Volume: 75, Issue:1

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Communication; Cell Count; Cell Cycle; Cell Line;

1998
Production of protoporphyrin IX induced by 5-aminolevulinic acid in transplanted human colon adenocarcinoma of nude mice can be increased by ultrasound.
    International journal of cancer, 1998, Nov-09, Volume: 78, Issue:4

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Colonic Neoplasms; Female; Humans; Mice; Mice, Inbred

1998
Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid.
    British journal of cancer, 2000, Volume: 83, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett E

2000
On the pharmacokinetics of topically applied 5-aminolevulinic acid and two of its esters.
    International journal of cancer, 2001, Apr-01, Volume: 92, Issue:1

    Topics: Adenocarcinoma; Administration, Cutaneous; Aminolevulinic Acid; Animals; Colonic Neoplasms; Female;

2001
The photosensitizing effect of the photoproduct of protoporphyrin IX.
    Journal of photochemistry and photobiology. B, Biology, 2001, Volume: 60, Issue:2-3

    Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Membrane; Humans; Methylene Blue; Photochemotherapy; Propi

2001
The effects of 5-aminolevulinic acid esters on protoporphyrin IX production in human adenocarcinoma cell lines.
    Photochemistry and photobiology, 2001, Volume: 74, Issue:5

    Topics: Adenocarcinoma; Aminolevulinic Acid; Dose-Response Relationship, Drug; Esters; Fibroblasts; Flow Cyt

2001
Photodynamic therapy of human Barrett's cancer using 5-aminolaevulinic acid-induced protoporphyrin IX: an in-vivo dosimetry study in athymic nude mice.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:6

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Barrett Esophagus; Esophageal Neoplasms; Humans; Mice;

2002