protoporphyrin ix has been researched along with Adenocarcinoma in 32 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This research aimed to assess the cytogenetic potential of 5-aminolevulinic acid (5-ALA) activated with laser irradiation (5-ALA/PDT) to damage the intact DNA of adenocarcinoma breast cancer cell line (MCF-7) and hepatocellular carcinoma cell line (HepG2)." | 7.88 | Photodynamic therapy using 5-aminolevulinic acid triggered DNA damage of adenocarcinoma breast cancer and hepatocellular carcinoma cell lines. ( Abo-Elfadl, MT; Abo-Zeid, MAM; Mostafa, SM, 2018) |
| "5-aminolevulinic acid heptyl ester was investigated in human adenocarcinoma WiDr cells and in healthy skin of athymic nude mice in comparison with 5-aminolevulinic acid (ALA)." | 7.75 | A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin. ( Iani, V; Juzeniene, A; Ma, LW; Moan, J; Pudroma, X, 2009) |
| "BALB/c nude mice bearing WiDr human colon adenocarcinoma were used to determine the effect of ultrasound on the production of 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) both in the tumors and in skin overlying the tumors." | 7.70 | Production of protoporphyrin IX induced by 5-aminolevulinic acid in transplanted human colon adenocarcinoma of nude mice can be increased by ultrasound. ( Iani, V; Ma, L; Moan, J; Peng, Q, 1998) |
| " This research aimed to assess the cytogenetic potential of 5-aminolevulinic acid (5-ALA) activated with laser irradiation (5-ALA/PDT) to damage the intact DNA of adenocarcinoma breast cancer cell line (MCF-7) and hepatocellular carcinoma cell line (HepG2)." | 3.88 | Photodynamic therapy using 5-aminolevulinic acid triggered DNA damage of adenocarcinoma breast cancer and hepatocellular carcinoma cell lines. ( Abo-Elfadl, MT; Abo-Zeid, MAM; Mostafa, SM, 2018) |
| "5-aminolevulinic acid heptyl ester was investigated in human adenocarcinoma WiDr cells and in healthy skin of athymic nude mice in comparison with 5-aminolevulinic acid (ALA)." | 3.75 | A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin. ( Iani, V; Juzeniene, A; Ma, LW; Moan, J; Pudroma, X, 2009) |
| " It is shown that sublethal PDT of human WiDr adenocarcinoma cells and D54Mg glioblastoma cells with 5-aminolevulinic acid (ALA), disulfonated tetraphenylporphyrine (TPPS(2a)), or MitoTracker Red (MTR) inhibits their trypsin-induced detachment from a plastic substratum." | 3.72 | Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum. ( Juzeniene, A; Ma, LW; Moan, J; Uzdensky, A, 2004) |
| "Human adenocarcinoma cells of the line WiDr and human leukemia T cells of the line Jurkat were incubated with 5-aminolevulinic acid and found to produce protoporphyrin IX (PpIX)." | 3.71 | Transfer of protoporphyrin IX between cells. ( Ma, LW; Moan, J; Stokke, T, 2002) |
| "The photodynamic effect of a photoproduct of protoporphyrin IX (PpIX) induced by 5-aminolevulinic acid (ALA) was investigated in WiDr cells, a human adenocarcinoma cell line." | 3.71 | The photosensitizing effect of the photoproduct of protoporphyrin IX. ( Bagdonas, S; Ma, L; Moan, J, 2001) |
| "Human colon adenocarcinoma cells (WiDr) and Chinese hamster lung fibroblasts cells (V79) were incubated with different concentrations of 5-aminolevulinic acid (ALA), and the production of protoporphyrin IX (PpIX) was studied using several techniques." | 3.70 | Protoporphyrin IX accumulation in cells treated with 5-aminolevulinic acid: dependence on cell density, cell size and cell cycle. ( Bech, O; Berg, K; Gaullier, JM; Ma, LW; Moan, J; Steen, HB; Stokke, T, 1998) |
| "BALB/c nude mice bearing WiDr human colon adenocarcinoma were used to determine the effect of ultrasound on the production of 5-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) both in the tumors and in skin overlying the tumors." | 3.70 | Production of protoporphyrin IX induced by 5-aminolevulinic acid in transplanted human colon adenocarcinoma of nude mice can be increased by ultrasound. ( Iani, V; Ma, L; Moan, J; Peng, Q, 1998) |
| "The response of human colon adenocarcinoma cells of the line WiDr to the combined treatment of ionizing radiation and photosensitization by 5-aminolevulinic acid-induced protoporphyrin IX was assessed by a colony-forming assay." | 3.69 | Combined treatment of ionizing radiation and photosensitization by 5-aminolevulinic acid-induced protoporphyrin IX. ( Berg, K; Luksiene, Z; Ma, L; Moan, J, 1995) |
| "Chinese hamster cells (V79) and human adenocarcinoma cells (WiDr) were incubated with 5-aminolevulinic acid (ALA) at different pH values and the rate of production of protoporphyrin IX (PpIX) was measured." | 3.69 | The pH dependency of protoporphyrin IX formation in cells incubated with 5-aminolevulinic acid. ( Bech, O; Berg, K; Moan, J, 1997) |
| "Human tumor cells of the lines WiDr (adenocarcinoma of the rectosigmoid colon), NHIK 3025 (carcinoma of the cervix), and V79 Chinese hamster fibroblasts were treated with 5-aminolevulinic acid (ALA) and ALA esterified to C1-C3 and C6-C8 chained aliphatic alcohols (ALA-esters)." | 3.69 | Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture. ( Anholt, H; Berg, K; Gaullier, JM; Ma, LW; Moan, J; Peng, Q; Selbo, PK, 1997) |
| "5-aminolevulinic acid (5-ALA) has been utilized for cancer diagnosis as a fluorescence probe." | 1.56 | 5-ALA-assistant automated detection of lymph node metastasis in gastric cancer patients. ( Harada, Y; Koshiishi, N; Matsumoto, T; Matsuo, H; Murayama, Y; Okochi, K; Otsuji, E; Takamatsu, T; Tanaka, H, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (37.50) | 18.2507 |
| 2000's | 14 (43.75) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Matsumoto, T | 1 |
| Murayama, Y | 2 |
| Matsuo, H | 1 |
| Okochi, K | 1 |
| Koshiishi, N | 1 |
| Harada, Y | 2 |
| Tanaka, H | 2 |
| Takamatsu, T | 2 |
| Otsuji, E | 2 |
| Abo-Zeid, MAM | 1 |
| Abo-Elfadl, MT | 1 |
| Mostafa, SM | 1 |
| Lualdi, M | 1 |
| Cavalleri, A | 1 |
| Battaglia, L | 1 |
| Colombo, A | 1 |
| Garrone, G | 1 |
| Morelli, D | 1 |
| Pignoli, E | 1 |
| Sottotetti, E | 1 |
| Leo, E | 1 |
| Yeh, SC | 1 |
| Sahli, S | 1 |
| Andrews, DW | 1 |
| Patterson, MS | 1 |
| Armstrong, D | 1 |
| Provias, J | 1 |
| Fang, Q | 1 |
| Koizumi, N | 1 |
| Beika, M | 1 |
| Minamikawa, T | 1 |
| Yamaoka, Y | 1 |
| Dai, P | 1 |
| Yanagisawa, A | 1 |
| Ascencio, M | 1 |
| Collinet, P | 1 |
| Farine, MO | 1 |
| Mordon, S | 1 |
| Casas, A | 1 |
| Battah, S | 1 |
| Di Venosa, G | 1 |
| Dobbin, P | 1 |
| Rodriguez, L | 1 |
| Fukuda, H | 2 |
| Batlle, A | 2 |
| MacRobert, AJ | 1 |
| Pudroma, X | 1 |
| Moan, J | 12 |
| Ma, LW | 6 |
| Iani, V | 3 |
| Juzeniene, A | 2 |
| Ziegler, VG | 1 |
| Knaup, J | 1 |
| Stahl, D | 1 |
| Krammer, B | 1 |
| Plaetzer, K | 1 |
| Krieg, RC | 3 |
| Messmann, H | 3 |
| Rauch, J | 1 |
| Seeger, S | 2 |
| Knuechel, R | 3 |
| Stokke, T | 3 |
| Ortner, MA | 1 |
| Ebert, B | 1 |
| Hein, E | 1 |
| Zumbusch, K | 1 |
| Nolte, D | 1 |
| Sukowski, U | 1 |
| Weber-Eibel, J | 1 |
| Fleige, B | 1 |
| Dietel, M | 1 |
| Stolte, M | 1 |
| Oberhuber, G | 1 |
| Porschen, R | 1 |
| Klump, B | 1 |
| Hörtnagl, H | 1 |
| Lochs, H | 1 |
| Rinneberg, H | 1 |
| Schlottmann, K | 1 |
| Endlicher, E | 2 |
| Schölmerich, J | 2 |
| Uzdensky, A | 1 |
| Alvarez, MG | 1 |
| Lacelli, MS | 1 |
| Rivarola, V | 1 |
| Berg, K | 6 |
| Luksiene, Z | 1 |
| Ma, L | 3 |
| Fromm, D | 2 |
| Kessel, D | 2 |
| Webber, J | 2 |
| Noodt, BB | 1 |
| Peng, Q | 4 |
| Nesland, JM | 1 |
| Wyss-Desserich, MT | 1 |
| Sun, CH | 1 |
| Wyss, P | 1 |
| Kurlawalla, CS | 1 |
| Haller, U | 1 |
| Berns, MW | 1 |
| Tadir, Y | 1 |
| Anholt, H | 2 |
| Bech, O | 3 |
| Gederaas, OA | 1 |
| Thorstensen, K | 1 |
| Romslo, I | 1 |
| Heyerdahl, H | 1 |
| Wang, I | 1 |
| Liu, DL | 1 |
| Berg, R | 1 |
| Andersson-Engels, S | 1 |
| Svanberg, S | 1 |
| Svanberg, K | 1 |
| Gaullier, JM | 2 |
| Selbo, PK | 1 |
| Steen, HB | 1 |
| Hinnen, P | 1 |
| de Rooij, FW | 1 |
| Terlouw, EM | 1 |
| Edixhoven, A | 1 |
| van Dekken, H | 1 |
| van Hillegersberg, R | 1 |
| Tilanus, HW | 1 |
| Wilson, JH | 1 |
| Siersema, PD | 1 |
| Bagdonas, S | 1 |
| Brunner, H | 1 |
| Hausmann, F | 1 |
| Pech, O | 1 |
| Nagy, CD | 1 |
| Gossner, L | 1 |
| May, A | 1 |
| Ell, C | 1 |
1 trial available for protoporphyrin ix and Adenocarcinoma
| Article | Year |
|---|---|
Side effects and photosensitization of human tissues after aminolevulinic acid.
Topics: Adenocarcinoma; Administration, Oral; Aminolevulinic Acid; Female; Gastrointestinal Neoplasms; Human | 1997 |
31 other studies available for protoporphyrin ix and Adenocarcinoma
| Article | Year |
|---|---|
5-ALA-assistant automated detection of lymph node metastasis in gastric cancer patients.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Fluorescent Dyes; Follo | 2020 |
Photodynamic therapy using 5-aminolevulinic acid triggered DNA damage of adenocarcinoma breast cancer and hepatocellular carcinoma cell lines.
Topics: Adenocarcinoma; Aminolevulinic Acid; Breast Neoplasms; Carcinoma, Hepatocellular; DNA Damage; Hep G2 | 2018 |
Early detection of colorectal adenocarcinoma: a clinical decision support tool based on plasma porphyrin accumulation and risk factors.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colorectal Neoplasms; Coproporphyrins; Early Diagnos | 2018 |
5-Aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett's esophagus cellular models.
Topics: Adenocarcinoma; Algorithms; Aminolevulinic Acid; Barrett Esophagus; Biomarkers; Esophageal Neoplasms | 2015 |
Highly sensitive fluorescence detection of metastatic lymph nodes of gastric cancer with photo-oxidation of protoporphyrin IX.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cell Line, Tumor; Female; Human | 2016 |
Protoporphyrin IX fluorescence photobleaching is a useful tool to predict the response of rat ovarian cancer following hexaminolevulinate photodynamic therapy.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Female; Microscopy, Fluorescence; Ovarian Neoplasms; P | 2008 |
Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Coloring Agents; Dend | 2009 |
A comparison of 5-aminolaevulinic acid- and its heptyl ester: dark cytotoxicity and protoporphyrin IX synthesis in human adenocarcinoma WiDr cells and in athymic nude mice healthy skin.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Line, Tumor; Drug Screening Assays, Antitumor; Hu | 2009 |
Fluorescence detection and depletion of T47D breast cancer cells from human mononuclear cell-enriched blood preparations by photodynamic treatment: Basic in vitro experiments towards the removal of circulating tumor cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Breast Neoplasms; Cell Line; Cell Line, Tumor; Endothe | 2011 |
Metabolic characterization of tumor cell-specific protoporphyrin IX accumulation after exposure to 5-aminolevulinic acid in human colonic cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship | 2002 |
Transfer of protoporphyrin IX between cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Communication; Cell Line, Tumor; Colonic Neoplasms; Humans | 2002 |
Time gated fluorescence spectroscopy in Barrett's oesophagus.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Biomarkers, | 2003 |
Intracellular localization is a cofactor for the phototoxicity of protoporphyrin IX in the gastrointestinal tract: in vitro study.
Topics: Adenocarcinoma; Colonic Neoplasms; Digestive System; Humans; Photochemotherapy; Photosensitizing Age | 2003 |
Photodynamic inhibition of enzymatic detachment of human cancer cells from a substratum.
Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Adhesion; Cell Line, Tumor; Cell Membrane; Cell Survival; | 2004 |
5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; D | 2007 |
Combined treatment of ionizing radiation and photosensitization by 5-aminolevulinic acid-induced protoporphyrin IX.
Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Cycle; Cell Division; Cell Line; Cell Survival; Colonic Ne | 1995 |
Feasibility of photodynamic therapy using endogenous photosensitization for colon cancer.
Topics: Adenocarcinoma; Administration, Oral; Aminolevulinic Acid; Biopsy; Colectomy; Colon, Sigmoid; Follow | 1996 |
Apoptosis and necrosis induced with light and 5-aminolaevulinic acid-derived protoporphyrin IX.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Apoptosis; Cells, Cultured; Colonic Neoplasms; Criceti | 1996 |
Accumulation of 5-aminolevulinic acid-induced protoporphyrin IX in normal and neoplastic human endometrial epithelial cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Cells, Cultured; Endometrial Neoplasms; Endometrium; Epithelial | 1996 |
The influence of iron chelators on the accumulation of protoporphyrin IX in 5-aminolaevulinic acid-treated cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Colonic Neoplasms; Cricetinae; Cricetulus; Dicarbethox | 1996 |
The effect of brief illumination on intracellular free calcium concentration in cells with 5-aminolevulinic acid-induced protoporphyrin IX synthesis.
Topics: Adenocarcinoma; Aminolevulinic Acid; Calcium; Colonic Neoplasms; Cytosol; DNA; Egtazic Acid; Fluores | 1996 |
The pH dependency of protoporphyrin IX formation in cells incubated with 5-aminolevulinic acid.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Survival; Colonic Neoplasms; Cricetinae; Fibrobla | 1997 |
Pharmacokinetic studies on 5-aminolevulinic acid-induced protoporphyrin IX accumulation in tumours and normal tissues.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Drug Interactions; Humans; Live | 1997 |
Use of 5-aminolevulinic acid esters to improve photodynamic therapy on cells in culture.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Colonic Neoplasms; Cricetinae; Cricetulus; Drug Screen | 1997 |
Protoporphyrin IX accumulation in cells treated with 5-aminolevulinic acid: dependence on cell density, cell size and cell cycle.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Communication; Cell Count; Cell Cycle; Cell Line; | 1998 |
Production of protoporphyrin IX induced by 5-aminolevulinic acid in transplanted human colon adenocarcinoma of nude mice can be increased by ultrasound.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Colonic Neoplasms; Female; Humans; Mice; Mice, Inbred | 1998 |
Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett E | 2000 |
On the pharmacokinetics of topically applied 5-aminolevulinic acid and two of its esters.
Topics: Adenocarcinoma; Administration, Cutaneous; Aminolevulinic Acid; Animals; Colonic Neoplasms; Female; | 2001 |
The photosensitizing effect of the photoproduct of protoporphyrin IX.
Topics: Adenocarcinoma; Aminolevulinic Acid; Cell Membrane; Humans; Methylene Blue; Photochemotherapy; Propi | 2001 |
The effects of 5-aminolevulinic acid esters on protoporphyrin IX production in human adenocarcinoma cell lines.
Topics: Adenocarcinoma; Aminolevulinic Acid; Dose-Response Relationship, Drug; Esters; Fibroblasts; Flow Cyt | 2001 |
Photodynamic therapy of human Barrett's cancer using 5-aminolaevulinic acid-induced protoporphyrin IX: an in-vivo dosimetry study in athymic nude mice.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Barrett Esophagus; Esophageal Neoplasms; Humans; Mice; | 2002 |