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protoporphyrin ix and Acute Liver Injury, Drug-Induced

protoporphyrin ix has been researched along with Acute Liver Injury, Drug-Induced in 3 studies

protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.

Research Excerpts

ExcerptRelevanceReference
"Combination of isoniazid (INH) and rifampicin (RFP) causes liver injury frequently among tuberculosis patients."3.85Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin. ( Deng, Y; Guo, Y; He, L; Li, C; Peng, W; Zuo, C, 2017)
" Treatment with 2500 ppm ACI for 26 weeks after initiation with diethylnitrosamine increased the incidence and multiplicities of altered foci and adenomas in hepatocytes from WT mice; these effects were significantly reduced in CARKO mice."3.83Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development. ( Ichimura, R; Inoue, K; Kodama, Y; Kuwata, K; Shibutani, M; Takahashi, M; Yoshida, M, 2016)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, F1
Lu, J1
Cheng, J1
Wang, L1
Matsubara, T1
Csanaky, IL1
Klaassen, CD1
Gonzalez, FJ1
Ma, X1
Kuwata, K1
Inoue, K1
Ichimura, R1
Takahashi, M1
Kodama, Y1
Shibutani, M1
Yoshida, M1
He, L1
Guo, Y1
Deng, Y1
Li, C1
Zuo, C1
Peng, W1

Other Studies

3 other studies available for protoporphyrin ix and Acute Liver Injury, Drug-Induced

ArticleYear
Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy.
    Nature medicine, 2013, Volume: 19, Issue:4

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antitubercular Agents; Chemical and Drug Induce

2013
Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 151, Issue:2

    Topics: Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cell Transformation, Neoplastic

2016
Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin.
    Xenobiotica; the fate of foreign compounds in biological systems, 2017, Volume: 47, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Chemical and Drug Induced L

2017