protoporphyrin ix has been researched along with Acute Liver Injury, Drug-Induced in 3 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Combination of isoniazid (INH) and rifampicin (RFP) causes liver injury frequently among tuberculosis patients." | 3.85 | Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin. ( Deng, Y; Guo, Y; He, L; Li, C; Peng, W; Zuo, C, 2017) |
| " Treatment with 2500 ppm ACI for 26 weeks after initiation with diethylnitrosamine increased the incidence and multiplicities of altered foci and adenomas in hepatocytes from WT mice; these effects were significantly reduced in CARKO mice." | 3.83 | Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development. ( Ichimura, R; Inoue, K; Kodama, Y; Kuwata, K; Shibutani, M; Takahashi, M; Yoshida, M, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, F | 1 |
| Lu, J | 1 |
| Cheng, J | 1 |
| Wang, L | 1 |
| Matsubara, T | 1 |
| Csanaky, IL | 1 |
| Klaassen, CD | 1 |
| Gonzalez, FJ | 1 |
| Ma, X | 1 |
| Kuwata, K | 1 |
| Inoue, K | 1 |
| Ichimura, R | 1 |
| Takahashi, M | 1 |
| Kodama, Y | 1 |
| Shibutani, M | 1 |
| Yoshida, M | 1 |
| He, L | 1 |
| Guo, Y | 1 |
| Deng, Y | 1 |
| Li, C | 1 |
| Zuo, C | 1 |
| Peng, W | 1 |
3 other studies available for protoporphyrin ix and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antitubercular Agents; Chemical and Drug Induce | 2013 |
Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development.
Topics: Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cell Transformation, Neoplastic | 2016 |
Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Chemical and Drug Induced L | 2017 |