protoporphyrin ix has been researched along with Acute Liver Injury, Drug-Induced in 3 studies
protoporphyrin IX: RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685
protoporphyrin : A cyclic tetrapyrrole that consists of porphyrin bearing four methyl substituents at positions 3, 8, 13 and 17, two vinyl substituents at positions 7 and 12 and two 2-carboxyethyl substituents at positions 2 and 18. The parent of the class of protoporphyrins.
Excerpt | Relevance | Reference |
---|---|---|
"Combination of isoniazid (INH) and rifampicin (RFP) causes liver injury frequently among tuberculosis patients." | 3.85 | Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin. ( Deng, Y; Guo, Y; He, L; Li, C; Peng, W; Zuo, C, 2017) |
" Treatment with 2500 ppm ACI for 26 weeks after initiation with diethylnitrosamine increased the incidence and multiplicities of altered foci and adenomas in hepatocytes from WT mice; these effects were significantly reduced in CARKO mice." | 3.83 | Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development. ( Ichimura, R; Inoue, K; Kodama, Y; Kuwata, K; Shibutani, M; Takahashi, M; Yoshida, M, 2016) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Li, F | 1 |
Lu, J | 1 |
Cheng, J | 1 |
Wang, L | 1 |
Matsubara, T | 1 |
Csanaky, IL | 1 |
Klaassen, CD | 1 |
Gonzalez, FJ | 1 |
Ma, X | 1 |
Kuwata, K | 1 |
Inoue, K | 1 |
Ichimura, R | 1 |
Takahashi, M | 1 |
Kodama, Y | 1 |
Shibutani, M | 1 |
Yoshida, M | 1 |
He, L | 1 |
Guo, Y | 1 |
Deng, Y | 1 |
Li, C | 1 |
Zuo, C | 1 |
Peng, W | 1 |
3 other studies available for protoporphyrin ix and Acute Liver Injury, Drug-Induced
Article | Year |
---|---|
Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antitubercular Agents; Chemical and Drug Induce | 2013 |
Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development.
Topics: Adenoma; Animals; Aryl Hydrocarbon Hydroxylases; Cell Proliferation; Cell Transformation, Neoplastic | 2016 |
Involvement of protoporphyrin IX accumulation in the pathogenesis of isoniazid/rifampicin-induced liver injury: the prevention of curcumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitubercular Agents; Chemical and Drug Induced L | 2017 |