protocatechuic acid has been researched along with Reperfusion Injury in 8 studies
protocatechuic acid: RN given refers to parent cpd; structure
3,4-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protocatechuic acid (PCA), which has antioxidant property, is a simple phenolic compound commonly found in many plants, vegetables, and fruits, notably in green tea and almonds." | 5.46 | Does protocatechuic acid, a natural antioxidant, reduce renal ischemia reperfusion injury in rats? ( Akşit, D; Akşit, H; Aslan, F; Başbuğ, M; Çavdar, F; Çıkman, Ö; Yıldar, M; Yüksel, M, 2017) |
| "Renal reperfusion injury was induced by clamping renal pedicle for 45 minutes after right nephrectomy was performed, followed by reperfusion for 3 hours." | 5.46 | Does protocatechuic acid, a natural antioxidant, reduce renal ischemia reperfusion injury in rats? ( Akşit, D; Akşit, H; Aslan, F; Başbuğ, M; Çavdar, F; Çıkman, Ö; Yıldar, M; Yüksel, M, 2017) |
| "Protocatechuic acid (PCA), which has been widely studied as a polyphenolic compound, induces expression of antioxidative genes that combat oxidative stress and cell apoptosis." | 5.40 | Modulating the p66shc signaling pathway with protocatechuic acid protects the intestine from ischemia-reperfusion injury and alleviates secondary liver damage. ( Chang, H; Chen, Z; Li, Z; Ma, L; Ma, Z; Tian, X; Wang, G; Wang, S; Yao, J; Zhao, H, 2014) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "Age, APACHE score at ICU admission, neurological disease, sepsis and duration of mechanical ventilation were all independent risk factors for the development of delirium in ICU patients." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "The aim of the study is to investigate the effects of Protocatechuic Acid (PCA), which is an antioxidant, anti-inflammatory and anti-apoptotic agent, on ovarian tissue and ovarian reserve against ischemia-reperfusion (IR) injury in a rat ovarian torsion model." | 4.31 | The effect of protocatechuic acid on ovarian histopathology and reserve in rat ovarian torsion model. ( Cetinkaya, A; Erimsah, S, 2023) |
| "A total of 24 Wistar adult female rats were divided into 3 groups as the control (sham operation, n = 8), IR (Ischemia-Reperfusion, n = 8), and IR+PCA (Ischemia-Reperfusion + 80 mg/kg protocatechuic acid, n = 8)." | 4.31 | The effect of protocatechuic acid on ovarian histopathology and reserve in rat ovarian torsion model. ( Cetinkaya, A; Erimsah, S, 2023) |
| "Protocatechuic acid (80 mg/kg) was administered to the IR+PCA group 30 minutes before reperfusion." | 1.91 | The effect of protocatechuic acid on ovarian histopathology and reserve in rat ovarian torsion model. ( Cetinkaya, A; Erimsah, S, 2023) |
| "Protocatechuic acid (PCA) is a natural polyphenol possessing anti-oxidant and anti-inflammatory activities." | 1.72 | Pharmacological Postconditioning by Protocatechuic Acid Attenuates Brain Injury in Ischemia-Reperfusion (I/R) Mice Model: Implications of Nuclear Factor Erythroid-2-Related Factor Pathway. ( Grewal, AK; Khan, H; Kumar, M; Singh, TG, 2022) |
| "Focal ischemia was induced by middle cerebral artery occlusion in adult male Wistar rats and confirmed by measuring infarction of brain by 2,3,5-Triphenyltetrazolium chloride (TTC) staining." | 1.62 | Protocatechuic Acid Prevents Early Hour Ischemic Reperfusion Brain Damage by Restoring Imbalance of Neuronal Cell Death and Survival Proteins. ( Ambulkar, S; Kale, S; Kharat, A; Prakash, A; Sakharkar, AJ; Sarode, LP; Ugale, RR, 2021) |
| "Protocatechuic acid (PCA), which has antioxidant property, is a simple phenolic compound commonly found in many plants, vegetables, and fruits, notably in green tea and almonds." | 1.46 | Does protocatechuic acid, a natural antioxidant, reduce renal ischemia reperfusion injury in rats? ( Akşit, D; Akşit, H; Aslan, F; Başbuğ, M; Çavdar, F; Çıkman, Ö; Yıldar, M; Yüksel, M, 2017) |
| "Renal reperfusion injury was induced by clamping renal pedicle for 45 minutes after right nephrectomy was performed, followed by reperfusion for 3 hours." | 1.46 | Does protocatechuic acid, a natural antioxidant, reduce renal ischemia reperfusion injury in rats? ( Akşit, D; Akşit, H; Aslan, F; Başbuğ, M; Çavdar, F; Çıkman, Ö; Yıldar, M; Yüksel, M, 2017) |
| "Protocatechuic acid (PCA), which has been widely studied as a polyphenolic compound, induces expression of antioxidative genes that combat oxidative stress and cell apoptosis." | 1.40 | Modulating the p66shc signaling pathway with protocatechuic acid protects the intestine from ischemia-reperfusion injury and alleviates secondary liver damage. ( Chang, H; Chen, Z; Li, Z; Ma, L; Ma, Z; Tian, X; Wang, G; Wang, S; Yao, J; Zhao, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, H | 1 |
| Grewal, AK | 1 |
| Kumar, M | 1 |
| Singh, TG | 1 |
| Erimsah, S | 1 |
| Cetinkaya, A | 1 |
| Kale, S | 1 |
| Sarode, LP | 1 |
| Kharat, A | 1 |
| Ambulkar, S | 1 |
| Prakash, A | 1 |
| Sakharkar, AJ | 1 |
| Ugale, RR | 1 |
| Ma, L | 1 |
| Wang, G | 1 |
| Chen, Z | 1 |
| Li, Z | 1 |
| Yao, J | 1 |
| Zhao, H | 1 |
| Wang, S | 1 |
| Ma, Z | 1 |
| Chang, H | 1 |
| Tian, X | 1 |
| Yüksel, M | 1 |
| Yıldar, M | 1 |
| Başbuğ, M | 1 |
| Çavdar, F | 1 |
| Çıkman, Ö | 1 |
| Akşit, H | 1 |
| Aslan, F | 1 |
| Akşit, D | 1 |
| Wang, GZ | 1 |
| Yao, JH | 1 |
| Jing, HR | 1 |
| Zhang, F | 1 |
| Lin, MS | 1 |
| Shi, L | 1 |
| Wu, H | 1 |
| Gao, DY | 1 |
| Liu, KX | 1 |
| Tian, XF | 1 |
| Ste-Marie, L | 1 |
| Vachon, P | 1 |
| Vachon, L | 1 |
| Bémeur, C | 1 |
| Guertin, MC | 1 |
| Montgomery, J | 1 |
1 review available for protocatechuic acid and Reperfusion Injury
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
1 trial available for protocatechuic acid and Reperfusion Injury
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
7 other studies available for protocatechuic acid and Reperfusion Injury
| Article | Year |
|---|---|
Pharmacological Postconditioning by Protocatechuic Acid Attenuates Brain Injury in Ischemia-Reperfusion (I/R) Mice Model: Implications of Nuclear Factor Erythroid-2-Related Factor Pathway.
Topics: Animals; Antioxidants; Brain; Brain Injuries; Brain Ischemia; Cerebral Infarction; Humans; Hydroxybe | 2022 |
The effect of protocatechuic acid on ovarian histopathology and reserve in rat ovarian torsion model.
Topics: Animals; Antioxidants; Female; Humans; Ischemia; Ovarian Diseases; Ovarian Torsion; Rats; Rats, Wist | 2023 |
Protocatechuic Acid Prevents Early Hour Ischemic Reperfusion Brain Damage by Restoring Imbalance of Neuronal Cell Death and Survival Proteins.
Topics: Animals; Apoptosis; Brain; Caspase 3; Cyclic AMP Response Element-Binding Protein; Disease Models, A | 2021 |
Modulating the p66shc signaling pathway with protocatechuic acid protects the intestine from ischemia-reperfusion injury and alleviates secondary liver damage.
Topics: Animals; Hydroxybenzoates; Intestinal Mucosa; Intestines; Liver Diseases; Male; Mice; Mice, Inbred I | 2014 |
Does protocatechuic acid, a natural antioxidant, reduce renal ischemia reperfusion injury in rats?
Topics: Acute Kidney Injury; Animals; Antioxidants; Hydroxybenzoates; Random Allocation; Rats; Rats, Sprague | 2017 |
Suppression of the p66shc adapter protein by protocatechuic acid prevents the development of lung injury induced by intestinal ischemia reperfusion in mice.
Topics: Animals; Anticarcinogenic Agents; bcl-X Protein; Disease Models, Animal; Hydroxybenzoates; Lung Inju | 2012 |
Hydroxyl radical production in the cortex and striatum in a rat model of focal cerebral ischemia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Cerebral Cortex; Cerebrovascular Circulat | 2000 |