protocatechuic acid has been researched along with Melanoma in 2 studies
protocatechuic acid: RN given refers to parent cpd; structure
3,4-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pear fruits are often used in traditional medicine for the treatment of melasma; therefore, we investigated the effects of pear extract (PE) and its component, protocatechuic acid (PCA), on melanogenesis in mouse melanoma cells." | 7.85 | Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells. ( Jeon, TI; Jeong, HY; Lee, YG; Moon, JH; Park, SH; Truong, XT, 2017) |
| " Pear fruits are often used in traditional medicine for the treatment of melasma; therefore, we investigated the effects of pear extract (PE) and its component, protocatechuic acid (PCA), on melanogenesis in mouse melanoma cells." | 3.85 | Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells. ( Jeon, TI; Jeong, HY; Lee, YG; Moon, JH; Park, SH; Truong, XT, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Truong, XT | 1 |
| Park, SH | 1 |
| Lee, YG | 1 |
| Jeong, HY | 1 |
| Moon, JH | 1 |
| Jeon, TI | 1 |
| Smit, NP | 1 |
| Pavel, S | 1 |
| Kammeyer, A | 1 |
| Westerhof, W | 1 |
2 other studies available for protocatechuic acid and Melanoma
| Article | Year |
|---|---|
Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells.
Topics: Animals; Humans; Hydroxybenzoates; Melanins; Melanocytes; Melanoma; Melanoma, Experimental; Mice; Mi | 2017 |
Determination of catechol O-methyltransferase activity in relation to melanin metabolism using high-performance liquid chromatography with fluorimetric detection.
Topics: Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Humans; Hydroxybenzoates; Melani | 1990 |