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protocatechuic acid and Melanoma

protocatechuic acid has been researched along with Melanoma in 2 studies

protocatechuic acid: RN given refers to parent cpd; structure
3,4-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
" Pear fruits are often used in traditional medicine for the treatment of melasma; therefore, we investigated the effects of pear extract (PE) and its component, protocatechuic acid (PCA), on melanogenesis in mouse melanoma cells."7.85Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells. ( Jeon, TI; Jeong, HY; Lee, YG; Moon, JH; Park, SH; Truong, XT, 2017)
" Pear fruits are often used in traditional medicine for the treatment of melasma; therefore, we investigated the effects of pear extract (PE) and its component, protocatechuic acid (PCA), on melanogenesis in mouse melanoma cells."3.85Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells. ( Jeon, TI; Jeong, HY; Lee, YG; Moon, JH; Park, SH; Truong, XT, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Truong, XT1
Park, SH1
Lee, YG1
Jeong, HY1
Moon, JH1
Jeon, TI1
Smit, NP1
Pavel, S1
Kammeyer, A1
Westerhof, W1

Other Studies

2 other studies available for protocatechuic acid and Melanoma

ArticleYear
Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells.
    International journal of molecular sciences, 2017, Aug-21, Volume: 18, Issue:8

    Topics: Animals; Humans; Hydroxybenzoates; Melanins; Melanocytes; Melanoma; Melanoma, Experimental; Mice; Mi

2017
Determination of catechol O-methyltransferase activity in relation to melanin metabolism using high-performance liquid chromatography with fluorimetric detection.
    Analytical biochemistry, 1990, Nov-01, Volume: 190, Issue:2

    Topics: Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Humans; Hydroxybenzoates; Melani

1990