protocatechuic acid has been researched along with Cerebral Hemorrhage in 3 studies
protocatechuic acid: RN given refers to parent cpd; structure
3,4-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protocatechuic acid (PCA) is a phenolic acid been proved neuroprotection in ICH without understanding of details." | 5.62 | Protocatechuic Acid Suppresses Microglia Activation and Facilitates M1 to M2 Phenotype Switching in Intracerebral Hemorrhage Mice. ( Bian, L; Chen, X; Sun, Q; Sun, Y; Wang, B; Xi, Z; Xu, C; Zhong, Z, 2021) |
| "Protocatechuic acid (PCA) has been proved possessing neuroprotection in ICH." | 5.56 | Protocatechuic acid attenuates brain edema and blood-brain barrier disruption after intracerebral hemorrhage in mice by promoting Nrf2/HO-1 pathway. ( Bian, L; Chen, X; Sun, Q; Sun, Y; Wang, B; Xi, Z; Xu, C; Zhong, Z, 2020) |
| "The brain edema following intracerebral hemorrhage (ICH) plays a key role in the recovery process." | 5.56 | Protocatechuic acid attenuates brain edema and blood-brain barrier disruption after intracerebral hemorrhage in mice by promoting Nrf2/HO-1 pathway. ( Bian, L; Chen, X; Sun, Q; Sun, Y; Wang, B; Xi, Z; Xu, C; Zhong, Z, 2020) |
| "Protocatechuic acid (PCA) is a phenolic acid been proved neuroprotection in ICH without understanding of details." | 1.62 | Protocatechuic Acid Suppresses Microglia Activation and Facilitates M1 to M2 Phenotype Switching in Intracerebral Hemorrhage Mice. ( Bian, L; Chen, X; Sun, Q; Sun, Y; Wang, B; Xi, Z; Xu, C; Zhong, Z, 2021) |
| "Protocatechuic acid (PCA) has been proved possessing neuroprotection in ICH." | 1.56 | Protocatechuic acid attenuates brain edema and blood-brain barrier disruption after intracerebral hemorrhage in mice by promoting Nrf2/HO-1 pathway. ( Bian, L; Chen, X; Sun, Q; Sun, Y; Wang, B; Xi, Z; Xu, C; Zhong, Z, 2020) |
| "The brain edema following intracerebral hemorrhage (ICH) plays a key role in the recovery process." | 1.56 | Protocatechuic acid attenuates brain edema and blood-brain barrier disruption after intracerebral hemorrhage in mice by promoting Nrf2/HO-1 pathway. ( Bian, L; Chen, X; Sun, Q; Sun, Y; Wang, B; Xi, Z; Xu, C; Zhong, Z, 2020) |
| "Protocatechuic acid (PCA) has been well studied for its neuroprotection value in several diseases, but the effect in intracerebral haemorrhage (ICH) has not been reported." | 1.51 | Protocatechuic acid exerts protective effects via suppression of the P38/JNK- NF-κB signalling pathway in an experimental mouse model of intracerebral haemorrhage. ( Bian, L; Chen, X; Hu, X; Ren, J; Sun, Q; Sun, Y; Wang, B; Xi, Z; Yang, GY; Yang, Y; Zhong, Z, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Xi, Z | 3 |
| Chen, X | 3 |
| Xu, C | 2 |
| Wang, B | 3 |
| Zhong, Z | 3 |
| Sun, Q | 3 |
| Sun, Y | 3 |
| Bian, L | 3 |
| Hu, X | 1 |
| Yang, Y | 1 |
| Ren, J | 1 |
| Yang, GY | 1 |
3 other studies available for protocatechuic acid and Cerebral Hemorrhage
| Article | Year |
|---|---|
Protocatechuic acid attenuates brain edema and blood-brain barrier disruption after intracerebral hemorrhage in mice by promoting Nrf2/HO-1 pathway.
Topics: Animals; Aquaporin 4; Blood-Brain Barrier; Brain; Brain Edema; Cerebral Hemorrhage; Gene Knockdown T | 2020 |
Protocatechuic Acid Suppresses Microglia Activation and Facilitates M1 to M2 Phenotype Switching in Intracerebral Hemorrhage Mice.
Topics: Adaptor Proteins, Signal Transducing; Animals; Anti-Inflammatory Agents; Cell Cycle Proteins; Cell L | 2021 |
Protocatechuic acid exerts protective effects via suppression of the P38/JNK- NF-κB signalling pathway in an experimental mouse model of intracerebral haemorrhage.
Topics: Animals; Apoptosis; Brain Edema; Cell Line, Tumor; Cerebral Hemorrhage; Cytokines; Disease Models, A | 2019 |