protocatechuic acid has been researched along with Brain Injuries in 4 studies
protocatechuic acid: RN given refers to parent cpd; structure
3,4-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protocatechuic acid (PCA) is a natural polyphenol possessing anti-oxidant and anti-inflammatory activities." | 1.72 | Pharmacological Postconditioning by Protocatechuic Acid Attenuates Brain Injury in Ischemia-Reperfusion (I/R) Mice Model: Implications of Nuclear Factor Erythroid-2-Related Factor Pathway. ( Grewal, AK; Khan, H; Kumar, M; Singh, TG, 2022) |
| "Protocatechuic acid groups were orally administered (50 &100 mg/kg) once daily for 10 consecutive days after cyclophosphamide injection." | 1.72 | Immunomodulatory effect of protocatechuic acid on cyclophosphamide induced brain injury in rat: Modulation of inflammosomes NLRP3 and SIRT1. ( Amin, MM; Elgohary, R; Elwahab, SA; Salama, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, H | 1 |
| Grewal, AK | 1 |
| Kumar, M | 1 |
| Singh, TG | 1 |
| Salama, A | 1 |
| Elgohary, R | 1 |
| Amin, MM | 1 |
| Elwahab, SA | 1 |
| Marklund, N | 2 |
| Lewander, T | 2 |
| Clausen, F | 2 |
| Hillered, L | 2 |
4 other studies available for protocatechuic acid and Brain Injuries
| Article | Year |
|---|---|
Pharmacological Postconditioning by Protocatechuic Acid Attenuates Brain Injury in Ischemia-Reperfusion (I/R) Mice Model: Implications of Nuclear Factor Erythroid-2-Related Factor Pathway.
Topics: Animals; Antioxidants; Brain; Brain Injuries; Brain Ischemia; Cerebral Infarction; Humans; Hydroxybe | 2022 |
Immunomodulatory effect of protocatechuic acid on cyclophosphamide induced brain injury in rat: Modulation of inflammosomes NLRP3 and SIRT1.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Brain Injuries; Caspase 3; Cyclophosphamide; Cytoki | 2022 |
Effects of the nitrone radical scavengers PBN and S-PBN on in vivo trapping of reactive oxygen species after traumatic brain injury in rats.
Topics: Animals; Benzenesulfonates; Blood-Brain Barrier; Brain Injuries; Cyclic N-Oxides; Free Radical Scave | 2001 |
Monitoring of reactive oxygen species production after traumatic brain injury in rats with microdialysis and the 4-hydroxybenzoic acid trapping method.
Topics: Animals; Blood Pressure; Body Temperature; Brain; Brain Injuries; Chromatography, High Pressure Liqu | 2001 |