protocatechuic acid has been researched along with B16 Melanoma in 3 studies
protocatechuic acid: RN given refers to parent cpd; structure
3,4-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pear fruits are often used in traditional medicine for the treatment of melasma; therefore, we investigated the effects of pear extract (PE) and its component, protocatechuic acid (PCA), on melanogenesis in mouse melanoma cells." | 7.85 | Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells. ( Jeon, TI; Jeong, HY; Lee, YG; Moon, JH; Park, SH; Truong, XT, 2017) |
| " Pear fruits are often used in traditional medicine for the treatment of melasma; therefore, we investigated the effects of pear extract (PE) and its component, protocatechuic acid (PCA), on melanogenesis in mouse melanoma cells." | 3.85 | Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells. ( Jeon, TI; Jeong, HY; Lee, YG; Moon, JH; Park, SH; Truong, XT, 2017) |
| "Finally, PCA inhibited metastasis of B16/F10 melanoma cells to the liver in mice." | 1.37 | Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-κB pathway and MMP-2 production by targeting RhoB activation. ( Chen, JH; Chou, FP; Lin, HH; Wang, CJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakashima, S | 1 |
| Matsuda, H | 1 |
| Oda, Y | 1 |
| Nakamura, S | 1 |
| Xu, F | 1 |
| Yoshikawa, M | 1 |
| Truong, XT | 1 |
| Park, SH | 1 |
| Lee, YG | 1 |
| Jeong, HY | 1 |
| Moon, JH | 1 |
| Jeon, TI | 1 |
| Lin, HH | 1 |
| Chen, JH | 1 |
| Chou, FP | 1 |
| Wang, CJ | 1 |
3 other studies available for protocatechuic acid and B16 Melanoma
| Article | Year |
|---|---|
Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells.
Topics: Agaricales; Animals; Antineoplastic Agents; Brassicaceae; Cell Proliferation; Cell Survival; Drug Sc | 2010 |
Protocatechuic Acid from Pear Inhibits Melanogenesis in Melanoma Cells.
Topics: Animals; Humans; Hydroxybenzoates; Melanins; Melanocytes; Melanoma; Melanoma, Experimental; Mice; Mi | 2017 |
Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-κB pathway and MMP-2 production by targeting RhoB activation.
Topics: Animals; Anticarcinogenic Agents; Blotting, Western; Down-Regulation; Electrophoretic Mobility Shift | 2011 |