protocatechuic acid has been researched along with Alloxan Diabetes in 11 studies
protocatechuic acid: RN given refers to parent cpd; structure
3,4-dihydroxybenzoic acid : A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protocatechuic acid (PCA) is a phenolic phytochemical widely reported to possess antidiabetic property." | 5.51 | Protocatechuic acid ameliorates neurobehavioral deficits via suppression of oxidative damage, inflammation, caspase-3 and acetylcholinesterase activities in diabetic rats. ( Adedara, IA; Ajayi, OM; Ayeni, MF; Farombi, EO; Fasina, OB, 2019) |
| "Protocatechuic acid (PCA) is a phenolic phytochemical widely reported to possess antidiabetic property." | 1.51 | Protocatechuic acid ameliorates neurobehavioral deficits via suppression of oxidative damage, inflammation, caspase-3 and acetylcholinesterase activities in diabetic rats. ( Adedara, IA; Ajayi, OM; Ayeni, MF; Farombi, EO; Fasina, OB, 2019) |
| "Protocatechuic acid (PCA) has been reported to exert antioxidant and anti-hyperglycemic activities." | 1.43 | Protocatechuic Acid Restores Vascular Responses in Rats With Chronic Diabetes Induced by Streptozotocin. ( Kongyingyoes, B; Kukongviriyapan, U; Pannangpetch, P; Semaming, Y; Thukhammee, W, 2016) |
| "Protocatechuic acid (PCA) is a phenolic compound, a main metabolite of anthocyanin, which has been reported to display various pharmacological properties." | 1.40 | Protocatechuic acid exerts a cardioprotective effect in type 1 diabetic rats. ( Chattipakorn, N; Chattipakorn, SC; Kumfu, S; Pannangpetch, P; Semaming, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Duman, KE | 1 |
| Dogan, A | 1 |
| Kaptaner, B | 1 |
| Abdelmageed, ME | 1 |
| Shehatou, GSG | 1 |
| Suddek, GM | 1 |
| Salem, HA | 1 |
| Oyedemi, SO | 1 |
| Eze, K | 1 |
| Aiyegoro, OA | 1 |
| Ibeh, RC | 1 |
| Ikechukwu, GC | 1 |
| Swain, SS | 1 |
| Ejiofor, E | 1 |
| Oyedemi, BO | 1 |
| Adedara, IA | 2 |
| Fasina, OB | 1 |
| Ayeni, MF | 1 |
| Ajayi, OM | 1 |
| Farombi, EO | 2 |
| Okpara, ES | 1 |
| Busari, EO | 1 |
| Omole, O | 1 |
| Owumi, SE | 1 |
| Semaming, Y | 3 |
| Kumfu, S | 1 |
| Pannangpetch, P | 3 |
| Chattipakorn, SC | 2 |
| Chattipakorn, N | 2 |
| Sripetchwandee, J | 1 |
| Sa-Nguanmoo, P | 1 |
| Pintana, H | 1 |
| Kukongviriyapan, U | 1 |
| Kongyingyoes, B | 1 |
| Thukhammee, W | 1 |
| Loarca-Piña, G | 1 |
| Mendoza, S | 1 |
| Ramos-Gómez, M | 1 |
| Reynoso, R | 1 |
| Harini, R | 2 |
| Pugalendi, KV | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Consumption of a Beverage of Chaya (Cnidoscolus Chayamansa) on Lipid Concentration, Lipid Peroxidation and Antioxidant Status of Patients With Dyslipidemia[NCT04110392] | 30 participants (Actual) | Interventional | 2019-06-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
11 other studies available for protocatechuic acid and Alloxan Diabetes
| Article | Year |
|---|---|
Ameliorative role of Cyanus depressus (M.Bieb.) Soják plant extract against diabetes-associated oxidative-stress-induced liver, kidney, and pancreas damage in rats.
Topics: Alanine Transaminase; Animals; Antioxidants; Apigenin; Aspartate Aminotransferases; Blood Glucose; C | 2022 |
Protocatechuic acid improves hepatic insulin resistance and restores vascular oxidative status in type-2 diabetic rats.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glycation End | 2021 |
Computational, chemical profiling and biochemical evaluation of antidiabetic potential of
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fa | 2022 |
Protocatechuic acid ameliorates neurobehavioral deficits via suppression of oxidative damage, inflammation, caspase-3 and acetylcholinesterase activities in diabetic rats.
Topics: Acetylcholinesterase; Animals; Antioxidants; Behavior, Animal; Caspase 3; Diabetes Mellitus, Experim | 2019 |
Dietary protocatechuic acid abrogates male reproductive dysfunction in streptozotocin-induced diabetic rats via suppression of oxidative damage, inflammation and caspase-3 activity.
Topics: Animals; Blood Glucose; Body Weight; Caspase 3; Diabetes Mellitus, Experimental; Diet; Hormones; Hyd | 2019 |
Protocatechuic acid exerts a cardioprotective effect in type 1 diabetic rats.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Blotting, Western; Cardiotonic Agents; Diabe | 2014 |
Protocatechuic acid protects brain mitochondrial function in streptozotocin-induced diabetic rats.
Topics: Animals; Anticarcinogenic Agents; Brain; Diabetes Mellitus, Experimental; Disease Models, Animal; Hy | 2015 |
Protocatechuic Acid Restores Vascular Responses in Rats With Chronic Diabetes Induced by Streptozotocin.
Topics: Animals; Antioxidants; Blood Glucose; Blood Pressure; Catalase; Diabetes Mellitus, Experimental; Hea | 2016 |
Antioxidant, antimutagenic, and antidiabetic activities of edible leaves from Cnidoscolus chayamansa Mc. Vaugh.
Topics: Animals; Antimutagenic Agents; Antioxidants; Catechin; Chromatography, High Pressure Liquid; Diabete | 2010 |
Antioxidant and antihyperlipidaemic activity of protocatechuic acid on streptozotocin-diabetic rats.
Topics: Animals; Antioxidants; Ascorbic Acid; Diabetes Mellitus, Experimental; Glutathione; Hydroxybenzoates | 2010 |
Antihyperglycemic effect of protocatechuic acid on streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glyburide; Glycated Hemoglobin | 2010 |