Page last updated: 2024-08-24

prostratin and HIV Infections

prostratin has been researched along with HIV Infections in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (37.93)	29.6817
2010's	12 (41.38)	24.3611
2020's	6 (20.69)	2.80

Authors

Authors	Studies
Akari, H; Irie, K; Kikumori, M; Murata, M; Seki, Y; Tan, W; Tang, Y; Wardani, NP; Washizaki, A	1
Covino, DA; Desimio, MG; Doria, M	1
Dong, KL; Gopee, K; Khathi, SP; Madlala, P; Maikoo, S; Mkhize, Z; Naicker, S; Ndung'u, T	1
Alcami, J; Bedoya, LM; Beltrán, M; Bueno, P; Cachet, X; Camarero, S; De la Torre-Tarazona, HE; Fernández-García, JL; Jiménez, R; Litaudon, M; Nothias, LF; Paolini, J; Román, L	1
Benner, NL; Chun, TW; Dimapasoc, M; Keenan, KN; Marsden, MD; Sloane, JL; Soliman, MSA; Wender, PA; Wu, X; Zack, JA; Zang, X	1
Ahmed, S; Curreli, F; Debnath, AK; Victor, SMB	1
Li, X; Lu, H; Lu, P; Ma, Z; Qu, X; Shen, Y; Wang, P; Wu, H; Xu, J; Zeng, H; Zhu, H; Zhu, X; Zhu, Y	1
Andersen, RJ; Brockman, MA; Brumme, ZL; de Silva, ED; Richard, K; Tietjen, I; Williams, DE	1
Andersen, RJ; Ntie-Kang, F; Tietjen, I	1
Beans, EJ; Chun, TW; Fournogerakis, D; Gauntlett, C; Heumann, LV; Kramer, R; Marsden, MD; Murray, D; Wender, PA; Zack, JA	1
Bhattacharyya, D; Chan, JK; Greene, WC; Lassen, KG; Ruelas, D	1
Bullen, CK; Durand, CM; Hill, AL; Laird, GM; Martin, AR; Rosenbloom, DI; Siliciano, JD; Siliciano, RF	1
Miana, GA; Paracha, RZ; Paracha, UZ; Riaz, M; Shahzad-ul-Hussan, S	1
Li, L; Li, M; Lin, J; Pan, X; Zeng, X; Zhang, M; Zhao, W	1
Gaj, T; Limsirichai, P; Schaffer, DV	1
Aweya, JJ; Chen, D; Chen, M; Chen, R; Chen, X; Chen, Y; Liu, M; Lu, J; Wang, H; Wu, X	1
Rochat, MA; Schlaepfer, E; Speck, RF	1
Hamer, D; Marsden, MD; Xu, J; Zack, JA	1
Banack, SA; Cox, PA; Johnson, HE	1
Avettand, V; Burny, A; Calao, M; Cherrier, T; Clumeck, N; Collette, Y; de Launoit, Y; De Wit, S; Demonte, D; Gatot, JS; Guiguen, A; Herbein, G; Kabeya, K; Lambotte, O; Lamine, A; Martinelli, V; Moutschen, M; Piette, J; Poutrel, S; Quivy, V; Reuse, S; Rohr, O; Rouzioux, C; Vaira, D; Van Lint, C; Vanhulle, C; Veithen, E	1
Abbas, W; Herbein, G; Tripathy, MK	1
Brooks, DG; Brown, S; Korin, YD; Korotzer, A; Zack, JA	1
Blumberg, PM; Bocklandt, S; Hamer, DH	1
Arlen, PA; Berger, EA; Bristol, G; Brooks, DG; Gao, L; Hamer, DH; Kitchen, CM; Zack, JA	1
Hamer, DH; Kulkosky, J; Pomerantz, RJ; Souder, E; Sullivan, J; Xu, Y	1
Hezareh, M	1
Darnell, GA; Gardner, J; Harrich, D; Suhrbier, A; Warrilow, D	1
Boyd, MR; Culnan, DM; Dornadula, G; Kulkosky, J; Pomerantz, RJ; Roman, J; Schnell, M	1

Reviews

4 review(s) available for prostratin and HIV Infections

Article	Year
Natural product-derived compounds in HIV suppression, remission, and eradication strategies. Antiviral research, 2018, Volume: 158 Topics: Anti-HIV Agents; Biological Products; Bryostatins; Depsipeptides; Disease Reservoirs; Diterpenes; Drug Discovery; Gene Products, tat; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Phorbol Esters; rev Gene Products, Human Immunodeficiency Virus; Virus Latency; Vorinostat	2018
Prostratin: An Overview. Mini reviews in medicinal chemistry, 2015, Volume: 15, Issue:13 Topics: Animals; Anti-HIV Agents; Antineoplastic Agents, Phytogenic; Drug Discovery; HIV Infections; HIV-1; Humans; Magnoliopsida; Neoplasms; Phorbol Esters; Protein Kinase C; Signal Transduction; Virus Internalization; Virus Latency	2015
Epigenetic regulation of HIV-1 transcription. Epigenomics, 2011, Volume: 3, Issue:4 Topics: Azepines; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Viral; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Histone-Lysine N-Methyltransferase; Histones; HIV Infections; HIV-1; Humans; Nucleosomes; Phorbol Esters; Piperazines; Quinazolines; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Virus Integration	2011
Prostratin as a new therapeutic agent targeting HIV viral reservoirs. Drug news & perspectives, 2005, Volume: 18, Issue:8 Topics: Animals; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; HIV Infections; HIV-1; Humans; Phorbol Esters; Protein Kinase C; Virus Activation; Virus Latency	2005

Other Studies

25 other study(ies) available for prostratin and HIV Infections

Article	Year
The Novel PKC Activator 10-Methyl-Aplog-1 Combined with JQ1 Induced Strong and Synergistic HIV Reactivation with Tolerable Global T Cell Activation. Viruses, 2021, 10-09, Volume: 13, Issue:10 Topics: Anti-HIV Agents; Azepines; Bryostatins; CD4-Positive T-Lymphocytes; Cell Line; HIV Infections; HIV-1; Humans; Lymphocyte Activation; Phorbol Esters; Signal Transduction; Triazoles; Virus Latency	2021
Impact of IL-15 and latency reversing agent combinations in the reactivation and NK cell-mediated suppression of the HIV reservoir. Scientific reports, 2022, 11-03, Volume: 12, Issue:1 Topics: CD4-Positive T-Lymphocytes; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Interleukin-15; Killer Cells, Natural; Panobinostat; Virus Activation; Virus Latency	2022
Genetic variation of the HIV-1 subtype C transmitted/founder viruses long terminal repeat elements and the impact on transcription activation potential and clinical disease outcomes. PLoS pathogens, 2023, Volume: 19, Issue:6 Topics: Gene Expression Regulation, Viral; Genetic Variation; HIV Infections; HIV Long Terminal Repeat; HIV-1; Humans; tat Gene Products, Human Immunodeficiency Virus; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha	2023
4-Deoxyphorbol inhibits HIV-1 infection in synergism with antiretroviral drugs and reactivates viral reservoirs through PKC/MEK activation synergizing with vorinostat. Biochemical pharmacology, 2020, Volume: 177 Topics: Anti-HIV Agents; Bryostatins; CD4-Positive T-Lymphocytes; Cell Survival; Drug Synergism; HIV Infections; HIV-1; Humans; Jurkat Cells; Mitogen-Activated Protein Kinase Kinases; Phorbol Esters; Protein Kinase C; Signal Transduction; Virus Activation; Virus Latency; Vorinostat	2020
Prodrugs of PKC modulators show enhanced HIV latency reversal and an expanded therapeutic window. Proceedings of the National Academy of Sciences of the United States of America, 2020, 05-19, Volume: 117, Issue:20 Topics: Animals; Anti-HIV Agents; Bryostatins; Cell Line, Tumor; Cells, Cultured; Diterpenes; HIV Infections; HIV-1; Humans; Mice; Mice, Inbred C57BL; Phorbol Esters; Prodrugs; Protein Kinase C; Virus Latency	2020
Identification of Combinations of Protein Kinase C Activators and Histone Deacetylase Inhibitors That Potently Reactivate Latent HIV. Viruses, 2020, 06-03, Volume: 12, Issue:6 Topics: CD4-Positive T-Lymphocytes; Drug Synergism; Enzyme Activation; Enzyme Activators; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Indoles; Lactams; Phenylbutyrates; Phorbol Esters; Protein Kinase C; Virus Activation; Virus Latency	2020
Reactivation of HIV-1 from Latency by an Ingenol Derivative from Euphorbia Kansui. Scientific reports, 2017, 08-25, Volume: 7, Issue:1 Topics: Anti-HIV Agents; Cell Death; Cell Survival; Cells, Cultured; Diterpenes; Drug Synergism; Drug Therapy, Combination; Euphorbia; HIV Infections; HIV-1; Humans; NF-kappa B; Phorbol Esters; Positive Transcriptional Elongation Factor B; Protein Kinase C; Signal Transduction; T-Lymphocytes; Transcriptional Activation; Virus Activation; Virus Latency	2017
Identification of Novel HIV-1 Latency-Reversing Agents from a Library of Marine Natural Products. Viruses, 2018, 06-27, Volume: 10, Issue:7 Topics: Anti-HIV Agents; Aquatic Organisms; Biological Products; CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Disulfides; Drug Discovery; High-Throughput Screening Assays; HIV Infections; HIV-1; Humans; Panobinostat; Phorbol Esters; Proviruses; Tyrosine; Virus Activation; Virus Latency	2018
Highly potent, synthetically accessible prostratin analogs induce latent HIV expression in vitro and ex vivo. Proceedings of the National Academy of Sciences of the United States of America, 2013, Jul-16, Volume: 110, Issue:29 Topics: Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Flow Cytometry; Gene Expression Regulation, Viral; HIV Infections; Humans; Lectins, C-Type; Magnetic Resonance Spectroscopy; Molecular Structure; Phorbol Esters; Protein Binding; Protein Kinase C; Virus Activation	2013
Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV. PloS one, 2013, Volume: 8, Issue:10 Topics: Calcineurin; Calcium; Calcium Signaling; CD4-Positive T-Lymphocytes; Cell Line, Tumor; HIV Infections; HIV Long Terminal Repeat; HIV-1; Humans; Jurkat Cells; Lymphocyte Activation; NF-kappa B; NFATC Transcription Factors; Phorbol Esters; Signal Transduction; Transcription Factors; Transcription, Genetic; Virus Latency	2013
Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations. The Journal of clinical investigation, 2015, Volume: 125, Issue:5 Topics: Adult; Anti-HIV Agents; Azepines; Bryostatins; CD4-Positive T-Lymphocytes; Cells, Cultured; Disulfiram; Drug Evaluation, Preclinical; Drug Synergism; Female; Histone Deacetylase Inhibitors; HIV Infections; HIV-1; Humans; Lymphocyte Activation; Lymphokines; Male; Middle Aged; Phorbol Esters; Protein Kinase C; RNA, Messenger; RNA, Viral; Transcription, Genetic; Triazoles; Virion; Virus Latency	2015
[Euphorbia fischeriana extract reactivates latent HIV through nuclear factor-κB pathway]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2015, Volume: 35, Issue:11 Topics: Euphorbia; Flow Cytometry; HIV; HIV Infections; Humans; NF-kappa B; Nitriles; Phorbol Esters; Plant Extracts; Signal Transduction; Sulfones; Tumor Necrosis Factor-alpha; Virus Latency	2015
CRISPR-mediated Activation of Latent HIV-1 Expression. Molecular therapy : the journal of the American Society of Gene Therapy, 2016, Volume: 24, Issue:3 Topics: Cell Line; Clustered Regularly Interspaced Short Palindromic Repeats; CRISPR-Cas Systems; Drug Synergism; Epigenesis, Genetic; Gene Editing; Gene Expression Regulation, Viral; Histone Deacetylase Inhibitors; HIV Infections; HIV Long Terminal Repeat; HIV-1; Humans; Phorbol Esters; Protein Binding; RNA, Guide, Kinetoplastida; Transcriptional Activation; Virus Activation; Virus Latency	2016
HMBA Enhances Prostratin-Induced Activation of Latent HIV-1 via Suppressing the Expression of Negative Feedback Regulator A20/TNFAIP3 in NF-κB Signaling. BioMed research international, 2016, Volume: 2016 Topics: Acetamides; Drug Synergism; Feedback, Physiological; Gene Expression Regulation; HEK293 Cells; HeLa Cells; HIV Infections; HIV-1; Humans; I-kappa B Proteins; NF-kappa B; Phorbol Esters; Phosphorylation; Positive Transcriptional Elongation Factor B; Proviruses; Signal Transduction; Transcriptional Activation; Tumor Necrosis Factor alpha-Induced Protein 3	2016
Promising Role of Toll-Like Receptor 8 Agonist in Concert with Prostratin for Activation of Silent HIV. Journal of virology, 2017, 02-15, Volume: 91, Issue:4 Topics: Adult; Animals; CD4 Lymphocyte Count; Cell Communication; Cell Line; Coculture Techniques; Dose-Response Relationship, Drug; Drug Synergism; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Mitogen-Activated Protein Kinases; Phorbol Esters; Protein Kinase C beta; Syk Kinase; T-Lymphocyte Subsets; Toll-Like Receptor 8; Tumor Necrosis Factor-alpha; Viral Load; Virus Activation; Virus Latency	2017
Short communication: Activating stimuli enhance immunotoxin-mediated killing of HIV-infected macrophages. AIDS research and human retroviruses, 2008, Volume: 24, Issue:11 Topics: Anti-HIV Agents; Cells, Cultured; Granulocyte-Macrophage Colony-Stimulating Factor; HIV Infections; Humans; Immunologic Factors; Immunotoxins; Leukocytes, Mononuclear; Macrophages; Phorbol Esters	2008
Variability in content of the anti-AIDS drug candidate prostratin in Samoan populations of Homalanthus nutans. Journal of natural products, 2008, Volume: 71, Issue:12 Topics: Anti-HIV Agents; Euphorbiaceae; HIV Infections; Humans; Phorbol Esters; Plant Bark; Plants, Medicinal; Samoa	2008
Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. PloS one, 2009, Jun-30, Volume: 4, Issue:6 Topics: Adult; Aged; Anti-HIV Agents; CD8-Positive T-Lymphocytes; Cell Nucleus; Cytoplasm; Drug Synergism; Enzyme Inhibitors; HIV Infections; HIV-1; Humans; I-kappa B Proteins; Middle Aged; Monocytes; NF-kappa B; NF-KappaB Inhibitor alpha; Nucleosomes; Phorbol Esters; Virus Latency	2009
Effects of prostratin on T-cell activation and human immunodeficiency virus latency. Journal of virology, 2002, Volume: 76, Issue:16 Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Cell Cycle; Disease Models, Animal; HIV Infections; HIV-1; Humans; In Vitro Techniques; Lectins, C-Type; Lymphocyte Activation; Mice; Mice, SCID; Phorbol Esters; Receptors, Interleukin-2; T-Lymphocytes; Virus Replication	2002
Activation of latent HIV-1 expression by the potent anti-tumor promoter 12-deoxyphorbol 13-phenylacetate. Antiviral research, 2003, Volume: 59, Issue:2 Topics: Anti-HIV Agents; Carcinogens; CD4 Antigens; Cell Line; Down-Regulation; Gene Expression Profiling; HIV Infections; HIV-1; Humans; Macromolecular Substances; Models, Molecular; Oligonucleotide Array Sequence Analysis; Phorbol Esters; Protein Kinase C; Receptors, CXCR4; Virus Activation; Virus Replication	2003
Molecular characterization, reactivation, and depletion of latent HIV. Immunity, 2003, Volume: 19, Issue:3 Topics: Adjuvants, Immunologic; Animals; HIV Core Protein p24; HIV Infections; HIV-1; Immunotoxins; Interleukin-7; Mice; Mice, SCID; Phorbol Esters; T-Lymphocytes; Virus Latency	2003
Expression of latent HAART-persistent HIV type 1 induced by novel cellular activating agents. AIDS research and human retroviruses, 2004, Volume: 20, Issue:5 Topics: Amino Acid Sequence; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; HIV Core Protein p24; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Muromonab-CD3; Phorbol Esters; Phytohemagglutinins	2004
HIV type 1 inhibition by protein kinase C modulatory compounds. AIDS research and human retroviruses, 2006, Volume: 22, Issue:9 Topics: CD4 Antigens; Cells, Cultured; Diterpenes; Down-Regulation; Gene Expression Regulation; HeLa Cells; HIV Infections; HIV-1; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Phorbol Esters; Protein Kinase C; Protein Kinase Inhibitors; Receptors, Chemokine; Tetradecanoylphorbol Acetate; Virus Activation; Virus Latency	2006
Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART. Blood, 2001, Nov-15, Volume: 98, Issue:10 Topics: Antiretroviral Therapy, Highly Active; CD4 Antigens; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Gene Expression Profiling; Gene Expression Regulation; HIV Infections; HIV-1; HL-60 Cells; Humans; Leukemia, Monocytic, Acute; Lymphocyte Activation; Monocytes; Myeloid Cells; Oligonucleotide Array Sequence Analysis; Phorbol Esters; Protein Kinase C; Proviruses; Receptors, CCR5; Receptors, CXCR4; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Viral Load; Virus Activation; Virus Latency	2001
New kinds of treatment. AIDS treatment news, 2001, Jan-25, Issue:377 Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adjuvants, Immunologic; Anti-HIV Agents; Enzyme Inhibitors; HIV Infections; Humans; Naltrexone; Phorbol Esters; Topoisomerase I Inhibitors	2001