prostaglandin-h2 has been researched along with Dermatitis* in 1 studies
1 other study(ies) available for prostaglandin-h2 and Dermatitis
| Article | Year |
|---|---|
Simultaneous HPLC determination of metabolites of the inflammatory cascade.
A model approach is presented to the in vivo inflammation cascade, in which the activities of key enzymes (phospholipase A2 [3.1.1.4], prostaglandin synthase [EC 1.14.99.1], and lipoxygenases [EC 1.13.11.12]) are determined simultaneously in a single in vitro assay.. Detection of phospholipids (up to 50 pM) and arachidonic acid (up to 33 pM) is attained with high sensitivity and without radiolabelling using a SEDERE light scattering detector.. Thus, in combination with a diode array UV-detector, lipids, prostaglandins, HETEs and other metabolites of the inflammation cascade can be determined with high efficiency using a reversed phase-high performance liquid chromatograph equipped with two highly sensitive detectors in series. Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Chromatography, High Pressure Liquid; Dermatitis; Lipoxygenase; Male; Phospholipases A; Phospholipases A2; Phospholipids; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins H; Sheep; Swine | 1997 |