prostaglandin-f1 has been researched along with Dermatitis--Contact* in 1 studies
1 other study(ies) available for prostaglandin-f1 and Dermatitis--Contact
| Article | Year |
|---|---|
Arachidonic acid metabolism in skin: experimental contact dermatitis in guinea pigs.
The cutaneous metabolism of exogenous arachidonic acid and endoperoxide (PGH2) to prostaglandins and hydroxy-fatty acids was investigated in experimental contact dermatitis in guinea pigs and compared to normal skin, unsensitized animals treated with the allergen dinitrochlorobenzene, and Trafuril-induced irritant dermatitis. The main alterations of cutaneous arachidonate metabolism in contact dermatitis comprise: (1) an inhibition of PGD2 synthesis; (2) a switch from predominant PGD2 production to a predominance of PGE2 and (3) a marked inhibition of the lipoxygenase activity. Topics: Animals; Arachidonic Acids; Chromatography, Thin Layer; Dermatitis, Contact; Dinitrochlorobenzene; Dinoprost; Dinoprostone; Female; Guinea Pigs; Lipoxygenase; Prostaglandins D; Prostaglandins E; Prostaglandins F; Skin | 1982 |