prostaglandin-f1 has been researched along with Arrhythmias--Cardiac* in 2 studies
2 other study(ies) available for prostaglandin-f1 and Arrhythmias--Cardiac
| Article | Year |
|---|---|
Influence of 15-keto-metabolites and 13,14-dihydro-15-keto-metabolites of PGE2 and PGF2 alpha as well as of 6-keto-PGF1 alpha as a metabolite of PGI2 on aconitine induced cardiac arrhythmia in rats.
The 15-keto-metabolites of PGE2 and PGF2 alpha produced an antiarrhythmic effect on aconitine induced arrhythmias in rats. The ED50 values of these metabolites were approximately 2.0 micrograms/kg. The 13,14-dihydro-15-keto-metabolites of PGE2 and PGF2 alpha had no statistically significant antiarrhythmic effect. PGI2 (0.25-1.00 micrograms/kg) produced an antiarrhythmic effect between 15-54% (ED50 0.75 micrograms/kg), whereas 6-keto-PGF1 alpha, a metabolite of PGI2, showed no significant antiarrhythmic effect. The results suggest a participation of 15-keto-metabolites in the antiarrhythmic effects of PGE2 and PGF2 alpha. Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dinoprost; Dinoprostone; Epoprostenol; Female; Male; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains | 1982 |
Prostaglandins show marked differences when tested against early ischemic dysrhythmias in rat.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Aspirin; Blood Pressure; Coronary Disease; Dinoprostone; Epoprostenol; Male; Prostaglandins; Prostaglandins E; Prostaglandins F; Quinidine; Rats | 1981 |