propylthiouracil and Ulcer

propylthiouracil has been researched along with Ulcer* in 3 studies

Reviews

1 review(s) available for propylthiouracil and Ulcer

Article	Year
Propylthiouracil-induced agranulocytosis: an unusual presentation and a possible mechanism. The American journal of medicine, 1988, Volume: 85, Issue:5 Topics: Adolescent; Agranulocytosis; Humans; Male; Mouth Diseases; Propylthiouracil; Thyrotoxicosis; Ulcer	1988

Other Studies

2 other study(ies) available for propylthiouracil and Ulcer

Article	Year
Intestinal ulcers due to drug-induced perinuclear anti-neutrophilic cytoplasmic antibody-positive vasculitis and antiphospholipid syndrome. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:4 Topics: Antibodies, Antineutrophil Cytoplasmic; Antiphospholipid Syndrome; Biopsy, Needle; Dose-Response Relationship, Drug; Endoscopy, Gastrointestinal; Female; Follow-Up Studies; Gastric Mucosa; Humans; Hyperthyroidism; Immunohistochemistry; Intestinal Diseases; Methylprednisolone; Middle Aged; Propylthiouracil; Severity of Illness Index; Treatment Outcome; Ulcer; Vasculitis, Leukocytoclastic, Cutaneous	2005
Colonic ulcers in propylthiouracil induced vasculitis with secondary antiphospholipid syndrome. Postgraduate medical journal, 2005, Volume: 81, Issue:955 A 48 year old white woman was admitted to the hospital because of several bouts of migratory polyarthritis, weight loss, fever, and abdominal pain over a period of 15 months. She had been taking propylthiouracil 100 mg daily for three years for hyperthyroidism treatment. A test for antineutrophil cytoplasmic autoantibodies (ANCA) was positive with a perinuclear pattern of staining. Antiphospholipid antibodies were also detected. Colonoscopy showed several ulcers on intestinal mucosa and the biopsy specimen showed intense microscopic vasculitis. The patient is well after methylprednisolone pulse therapy and eight months of oral azathioprine. A surveillance colonoscopy showed complete healing of intestinal ulcers. No recurrence of symptoms has occurred and autoantibodies are negative, 10 months after treatment finished. The sequence of events suggests a propylthiouracil induced vasculitis p-ANCA positive and an antiphospholipid syndrome. This is the first report of colonic ulcers diagnosed and successfully treated in such circumstances. Topics: Antiphospholipid Syndrome; Antithyroid Agents; Colonic Diseases; Female; Humans; Hyperthyroidism; Middle Aged; Propylthiouracil; Ulcer; Vasculitis	2005

Article

Year

Intestinal ulcers due to drug-induced perinuclear anti-neutrophilic cytoplasmic antibody-positive vasculitis and antiphospholipid syndrome.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2005, Volume: 3, Issue:4

Topics: Antibodies, Antineutrophil Cytoplasmic; Antiphospholipid Syndrome; Biopsy, Needle; Dose-Response Relationship, Drug; Endoscopy, Gastrointestinal; Female; Follow-Up Studies; Gastric Mucosa; Humans; Hyperthyroidism; Immunohistochemistry; Intestinal Diseases; Methylprednisolone; Middle Aged; Propylthiouracil; Severity of Illness Index; Treatment Outcome; Ulcer; Vasculitis, Leukocytoclastic, Cutaneous

2005

Colonic ulcers in propylthiouracil induced vasculitis with secondary antiphospholipid syndrome.

Postgraduate medical journal, 2005, Volume: 81, Issue:955

A 48 year old white woman was admitted to the hospital because of several bouts of migratory polyarthritis, weight loss, fever, and abdominal pain over a period of 15 months. She had been taking propylthiouracil 100 mg daily for three years for hyperthyroidism treatment. A test for antineutrophil cytoplasmic autoantibodies (ANCA) was positive with a perinuclear pattern of staining. Antiphospholipid antibodies were also detected. Colonoscopy showed several ulcers on intestinal mucosa and the biopsy specimen showed intense microscopic vasculitis. The patient is well after methylprednisolone pulse therapy and eight months of oral azathioprine. A surveillance colonoscopy showed complete healing of intestinal ulcers. No recurrence of symptoms has occurred and autoantibodies are negative, 10 months after treatment finished. The sequence of events suggests a propylthiouracil induced vasculitis p-ANCA positive and an antiphospholipid syndrome. This is the first report of colonic ulcers diagnosed and successfully treated in such circumstances.

Topics: Antiphospholipid Syndrome; Antithyroid Agents; Colonic Diseases; Female; Humans; Hyperthyroidism; Middle Aged; Propylthiouracil; Ulcer; Vasculitis

2005