propylthiouracil and Tuberculosis--Pulmonary

propylthiouracil has been researched along with Tuberculosis--Pulmonary* in 1 studies

Other Studies

1 other study(ies) available for propylthiouracil and Tuberculosis--Pulmonary

ArticleYear
Concomitant drug- and infection-induced antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis with multispecific ANCA.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2012, Volume: 21, Issue:5

    To report the first case of concomitant drug- and infection-induced antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) in a patient treated with propylthiouracil (PTU) and suffering from tuberculosis.. A 28-year-old woman with PTU-treated hyperthyroidism presented with fever, purpura, pulmonary cavitations and ANCA to myeloperoxidase, bactericidal/permeability-increasing protein (BPI), proteinase-3 and elastase. Skin histopathology confirmed vasculitis. However, sputum examination revealed Mycobacterium tuberculosis. Remission was achieved after PTU withdrawal and treatment with antituberculosis drugs.. Our case confirmed that BPI-ANCA are elevated in active tuberculosis. Multispecific ANCA were helpful for the diagnosis of concomitant PTU- and M. tuberculosis-induced AAV.

    Topics: Adult; Antibodies, Antineutrophil Cytoplasmic; Antithyroid Agents; Antitubercular Agents; Female; Humans; Hyperthyroidism; Propylthiouracil; Tuberculosis, Pulmonary; Vasculitis

2012