propylthiouracil and Hypoparathyroidism

Topics: Adult; Calcium; Carbimazole; Congenital Hypothyroidism; Dihydrotachysterol; Female; Humans; Hyperparathyroidism; Hyperthyroidism; Hypoparathyroidism; Hypothyroidism; Infant, Newborn; Parathyroid Diseases; Parathyroid Glands; Pregnancy; Pregnancy Complications; Propylthiouracil; Puerperal Disorders; Thyroid Diseases; Thyroxine

We report a case of 26-year-old woman with Graves' disease and idiopathic hypoparathyroidism diagnosed at 11 years of age, who subsequently developed insulin-dependent diabetes mellitus (IDDM) at 17 years of age. Treatment with antithyroid agents had failed to control her Graves' disease and her IDDM was unmanageable despite insulin therapy. Surgical intervention was carried out, resulting in an improvement of both her hyperthyroidism and IDDM. This case is the first report of polyglandular autoimmune (PGA) syndrome, presenting the association of IDDM, Graves' disease and idiopathic hypoparathyroidism.

Topics: Adult; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Female; Glycosuria; Graves Disease; Humans; Hypoparathyroidism; Insulin; Propylthiouracil; Thyroid Hormones

Topics: Adolescent; Female; Goiter; Hemorrhage; Humans; Hyperthyroidism; Hypoparathyroidism; Hypothyroidism; Iodine; Methylthiouracil; Postoperative Care; Postoperative Complications; Potassium Iodide; Preoperative Care; Propylthiouracil; Thyroid Diseases; Thyroidectomy; Thyroiditis; Time Factors; Vocal Cord Paralysis

Topics: Adolescent; Anesthesia, General; Carbimazole; Female; Follow-Up Studies; Goiter; Halothane; Horner Syndrome; Humans; Hyperthyroidism; Hypoparathyroidism; Laryngeal Edema; Male; Nitrous Oxide; Oxygen; Postoperative Complications; Preoperative Care; Propylthiouracil; Thyroidectomy; Thyroxine; Tracheotomy

Topics: Adolescent; Calcium; Calcium, Dietary; Child; Drug Therapy; Humans; Hyperthyroidism; Hypoparathyroidism; Infant; Postoperative Complications; Propylthiouracil; Thyroid Hormones; Thyroidectomy; Thyrotoxicosis; Vitamin D; Vocal Cord Paralysis