propylthiouracil and Hypokalemic-Periodic-Paralysis

propylthiouracil has been researched along with Hypokalemic-Periodic-Paralysis* in 5 studies

Other Studies

5 other study(ies) available for propylthiouracil and Hypokalemic-Periodic-Paralysis

ArticleYear
Thyrotoxic periodic paralysis: an endocrine cause of paraparesis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2014, Volume: 24 Suppl 2

    Periodic paralysis is a muscle disorder that belongs to the family of diseases called channelopathies, manifested by episodes of painless muscle weakness. Periodic paralysis is classified as hypokalemic when episodes occur in association with low potassium levels. Most cases are hereditary. Acquired cases have been described in association with hyperthyroidism. Diagnosis is made on clinical and biochemical grounds. Patients may be markedly hypokalemic during the episode and respond well to potassium supplementation. Episodes can be prevented by achieving a euthyroid state. This report describes a young gentleman presenting with thyrotoxic hypokalemic paraparesis. The condition needs to be considered in the differential diagnosis of neuromuscular weakness in the context of hypokalemia by the treating physicians.

    Topics: Adult; Antithyroid Agents; Graves Disease; Humans; Hyperthyroidism; Hypokalemic Periodic Paralysis; Male; Muscle Weakness; Paraparesis; Potassium; Propranolol; Propylthiouracil; Thyroid Function Tests; Thyrotoxicosis; Treatment Outcome

2014
Hypokalemic periodic paralysis associated with thyrotoxicosis, renal tubular acidosis and nephrogenic diabetes insipidus.
    Endocrine journal, 2010, Volume: 57, Issue:4

    A 19-year-old girl presented at our emergency room with hypokalemic periodic paralysis. She had a thyrotoxic goiter and had experienced three paralytic attacks during the previous 2 years on occasions when she stopped taking antithyroid drugs. In addition to thyrotoxic periodic paralysis (TPP), she had metabolic acidosis, urinary potassium loss, polyuria and polydipsia. Her reduced ability to acidify urine during spontaneous metabolic acidosis was confirmed by detection of coexisting distal renal tubular acidosis (RTA). The polyuria and polydipsia were caused by nephrogenic diabetes insipidus, which was diagnosed using the water deprivation test and vasopressin administration. Her recurrent and frequent paralytic attacks may have been the combined effects of thyrotoxicosis and RTA. Although the paralytic attack did not recur after improving the thyroid function, mild acidosis and nephrogenic DI have been remained subsequently. Patients with TPP, especially females with atypical metabolic features, should be investigated for possible precipitating factors.

    Topics: Acidosis, Renal Tubular; Adult; Antithyroid Agents; Diabetes Insipidus, Nephrogenic; Female; Goiter; Humans; Hypokalemic Periodic Paralysis; Medication Adherence; Polyuria; Propylthiouracil; Recurrence; Thyrotoxicosis; Vasopressins; Water Deprivation

2010
Hypokalemic periodic paralysis due to Graves Disease.
    The American journal of medicine, 2009, Volume: 122, Issue:12

    Topics: Adult; Anti-Arrhythmia Agents; Antithyroid Agents; Anxiety; Arrhythmias, Cardiac; Dyspnea; Graves Disease; Humans; Hypokalemic Periodic Paralysis; Malaysia; Male; Methimazole; Muscle Weakness; Neurologic Examination; Potassium; Propranolol; Propylthiouracil; Sleep Initiation and Maintenance Disorders; Tremor; Weight Loss

2009
An unusual cause of muscle weakness: a case report.
    The American journal of the medical sciences, 2006, Volume: 332, Issue:3

    Thyrotoxic hypokalemic periodic paralysis (THPP) has been reported earlier in the Asian population. However, it is now becoming increasingly common in the Western countries as well. Thus, its in-depth knowledge is a must for every physician so that this diagnosis is not overlooked in any case presenting with extremity weakness and paralysis, especially considering its reversible nature. We present an interesting case of THPP in a Vietnamese patient presenting with bilateral lower extremity weakness and extremely low serum potassium levels. We also present a comprehensive discussion and review of literature related to THPP, which would be helpful for the internists to diagnose and appropriately manage this disease.

    Topics: Adrenergic beta-Antagonists; Antithyroid Agents; Asian People; Humans; Hypokalemic Periodic Paralysis; Male; Middle Aged; Propranolol; Propylthiouracil; Thyrotoxicosis; Vietnam

2006
Thyrotoxic periodic paralysis complicated by near-fatal ventricular arrhythmias.
    Singapore medical journal, 2005, Volume: 46, Issue:2

    A 35-year-old Chinese man presented with acute thyrotoxic periodic paralysis complicated by near-fatal cardiac arrhythmias due to persistent hypokalaemia, despite maximum potassium supplementation. He was eventually resuscitated with external cadioversion. In this unusual case of severe refractory hypokalaemia leading to ventricular fibrillation in a patient with underlying thyrotoxicosis, the potential dangers concerning the use of dextrose infusion and beta-adrenergic agent for resuscitation are highlighted.

    Topics: Adult; Antithyroid Agents; Glucose; Humans; Hypokalemic Periodic Paralysis; Male; Propylthiouracil; Sweetening Agents; Thyrotoxicosis; Ventricular Fibrillation

2005