propylthiouracil and Hemorrhagic-Disorders

propylthiouracil has been researched along with Hemorrhagic-Disorders* in 3 studies

Other Studies

3 other study(ies) available for propylthiouracil and Hemorrhagic-Disorders

ArticleYear
Propylthiouracil-related hemorrhagic diathesis: a case report and review of the literature.
    The Mount Sinai journal of medicine, New York, 2006, Volume: 73, Issue:7

    We present an unusual case of a drug-related hemorrhagic diathesis. One month prior to admission, the patient was diagnosed at another medical center as having Graves' disease and propylthiouracil therapy (PTU) was initiated. Since clinical recovery was not achieved, the PTU was quickly increased to an unconventional daily dose of 1,000 mg. The patient was referred to our hospital because of spontaneous epistaxis, multiple ecchymoses and prolonged prothrombin time (PT) and activated partial thromboplastin time (aPTT), which developed soon after the increase in PTU dose. Drug-related hemorrhagic diathesis was considered, after other possible causes had been eliminated. To the best of our knowledge, this is the first reported case of spontaneous hemorrhage due to PTU use.

    Topics: Adult; Antithyroid Agents; Female; Graves Disease; Hemorrhagic Disorders; Humans; Partial Thromboplastin Time; Propylthiouracil; Prothrombin Time

2006
Hypoprothrombinemia due to propylthiouracil therapy.
    JAMA, 1960, Jul-02, Volume: 173

    Topics: Hemorrhagic Disorders; Humans; Hypoprothrombinemias; Propylthiouracil; Thiouracil

1960
Deficiency of prothrombin and proconvertin after therapy with propylthiouracil.
    Journal of the American Medical Association, 1959, Dec-26, Volume: 171

    Topics: Blood Coagulation Tests; Factor VII; Hemorrhagic Disorders; Hemostatics; Humans; Propylthiouracil; Prothrombin; Thiouracil

1959