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propylene glycol and Status Epilepticus

propylene glycol has been researched along with Status Epilepticus in 3 studies

Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.

Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Research Excerpts

ExcerptRelevanceReference
"To report a case of probable propylene glycol (PG) toxicity in a patient receiving continuous infusion of pentobarbital for refractory status epilepticus."7.74Propylene glycol-induced lactic acidosis in a patient receiving continuous infusion pentobarbital. ( Forni, A; Miller, MA; Yogaratnam, D, 2008)
"We present a case of propylene glycol toxicity associated with the use of high-dose intravenous pentobarbital and phenobarbital during the treatment of refractory status epilepticus."7.74Propylene glycol toxicity complicating use of barbiturate coma. ( Bledsoe, KA; Kramer, AH, 2008)
"A case of propylene glycol poisoning is described in a 39 year old woman which resulted in her admission to hospital in status epilepticus."7.67Cerebral depression due to propylene glycol in a patient with chronic epilepsy--the value of the plasma osmolal gap in diagnosis. ( Flanagan, RJ; Francis, DA; Lascelles, PT; Little, P; Lolin, Y, 1988)
"To report a case of probable propylene glycol (PG) toxicity in a patient receiving continuous infusion of pentobarbital for refractory status epilepticus."3.74Propylene glycol-induced lactic acidosis in a patient receiving continuous infusion pentobarbital. ( Forni, A; Miller, MA; Yogaratnam, D, 2008)
"We present a case of propylene glycol toxicity associated with the use of high-dose intravenous pentobarbital and phenobarbital during the treatment of refractory status epilepticus."3.74Propylene glycol toxicity complicating use of barbiturate coma. ( Bledsoe, KA; Kramer, AH, 2008)
"A case of propylene glycol poisoning is described in a 39 year old woman which resulted in her admission to hospital in status epilepticus."3.67Cerebral depression due to propylene glycol in a patient with chronic epilepsy--the value of the plasma osmolal gap in diagnosis. ( Flanagan, RJ; Francis, DA; Lascelles, PT; Little, P; Lolin, Y, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, MA1
Forni, A1
Yogaratnam, D1
Bledsoe, KA1
Kramer, AH1
Lolin, Y1
Francis, DA1
Flanagan, RJ1
Little, P1
Lascelles, PT1

Other Studies

3 other studies available for propylene glycol and Status Epilepticus

ArticleYear
Propylene glycol-induced lactic acidosis in a patient receiving continuous infusion pentobarbital.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:10

    Topics: Acidosis, Lactic; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Middle Aged; Pent

2008
Propylene glycol toxicity complicating use of barbiturate coma.
    Neurocritical care, 2008, Volume: 9, Issue:1

    Topics: Adult; Anticonvulsants; Barbiturates; Coma; Critical Care; Fatal Outcome; Humans; Infusions, Intrave

2008
Cerebral depression due to propylene glycol in a patient with chronic epilepsy--the value of the plasma osmolal gap in diagnosis.
    Postgraduate medical journal, 1988, Volume: 64, Issue:754

    Topics: Acidosis; Adult; Epilepsy; Female; Humans; Osmolar Concentration; Propylene Glycol; Propylene Glycol

1988