propylene glycol has been researched along with Drug Overdose in 2 studies
Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.
Drug Overdose: Accidental or deliberate use of a medication or street drug in excess of normal dosage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propylene glycol is a diluent found in many intravenous and oral drugs, including phenytoin, diazepam, and lorazepam." | 5.36 | Severe lactic acidosis after an iatrogenic propylene glycol overdose. ( Egelhoff, E; Heard, K; Zosel, A, 2010) |
| "Ingestion of massive doses of propylene glycol, previously not reported as a cause of D-lactic acidosis, should be added to the differential diagnosis of this rare condition." | 3.72 | Unusual D-lactic acid acidosis from propylene glycol metabolism in overdose. ( Coucke, V; Couttenye, MM; Demey, HE; Jorens, PG; Schepens, PJ; Van Hoof, V; Verpooten, GA, 2004) |
| "Propylene glycol is a diluent found in many intravenous and oral drugs, including phenytoin, diazepam, and lorazepam." | 1.36 | Severe lactic acidosis after an iatrogenic propylene glycol overdose. ( Egelhoff, E; Heard, K; Zosel, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zosel, A | 1 |
| Egelhoff, E | 1 |
| Heard, K | 1 |
| Jorens, PG | 1 |
| Demey, HE | 1 |
| Schepens, PJ | 1 |
| Coucke, V | 1 |
| Verpooten, GA | 1 |
| Couttenye, MM | 1 |
| Van Hoof, V | 1 |
2 other studies available for propylene glycol and Drug Overdose
| Article | Year |
|---|---|
Severe lactic acidosis after an iatrogenic propylene glycol overdose.
Topics: Acidosis, Lactic; Drug Overdose; Humans; Iatrogenic Disease; Infusions, Intravenous; Male; Pharmaceu | 2010 |
Unusual D-lactic acid acidosis from propylene glycol metabolism in overdose.
Topics: Acidosis, Lactic; Aged; Brain Diseases, Metabolic; Drug Overdose; Fatal Outcome; Humans; Male; Propy | 2004 |