propylene glycol has been researched along with Coronary Disease in 2 studies
Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We found that this solvent, used in a commercially available IV nitroglycerin solution, may cause hyperosmolality, hemolysis and lactic acidosis." | 3.67 | Propylene glycol-induced side effects during intravenous nitroglycerin therapy. ( Bossaert, LL; Daelemans, RA; De Broe, ME; Demey, HE; Lakiere, FV; Schepens, PJ; Van Campenhout, CM; Verpooten, GA, 1988) |
| " Patients treated with simultaneous IV nitroglycerin and IV heparin must be monitored often to avoid inadequate anticoagulation, and heparin dosage should be decreased when stopping IV nitroglycerin therapy to avoid hemorrhage." | 1.27 | Heparin resistance induced by intravenous nitroglycerin. A word of caution when both drugs are used concomitantly. ( Habbab, MA; Haft, JI, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Habbab, MA | 1 |
| Haft, JI | 1 |
| Demey, HE | 1 |
| Daelemans, RA | 1 |
| Verpooten, GA | 1 |
| De Broe, ME | 1 |
| Van Campenhout, CM | 1 |
| Lakiere, FV | 1 |
| Schepens, PJ | 1 |
| Bossaert, LL | 1 |
2 other studies available for propylene glycol and Coronary Disease
| Article | Year |
|---|---|
Heparin resistance induced by intravenous nitroglycerin. A word of caution when both drugs are used concomitantly.
Topics: Adult; Coronary Disease; Drug Resistance; Drug Therapy, Combination; Heparin; Heparin Antagonists; H | 1987 |
Propylene glycol-induced side effects during intravenous nitroglycerin therapy.
Topics: Acidosis, Lactic; Adult; Aged; Coronary Disease; Female; Hemolysis; Humans; Kidney; Male; Middle Age | 1988 |