Page last updated: 2024-10-20

propylene glycol and Brain Swelling

propylene glycol has been researched along with Brain Swelling in 2 studies

Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.

Research Excerpts

ExcerptRelevanceReference
"For the treatment of postoperative seizures and prevention of brain edema, an etomidate drip was used in conjunction with phenytoin, diazepam, pentobarbital, and phenobarbital in a 70-year-old woman."3.68A case of propylene glycol toxic reaction associated with etomidate infusion. ( Bedichek, E; Kirschbaum, B, 1991)
" We believed that this represented an adverse effect that was probably related to the study drug and the study was stopped."2.68Propylene glycol toxicity following continuous etomidate infusion for the control of refractory cerebral edema. ( Aranda, M; Giannotta, SL; Levy, ML; Zelman, V, 1995)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Levy, ML1
Aranda, M1
Zelman, V1
Giannotta, SL1
Bedichek, E1
Kirschbaum, B1

Trials

1 trial available for propylene glycol and Brain Swelling

ArticleYear
Propylene glycol toxicity following continuous etomidate infusion for the control of refractory cerebral edema.
    Neurosurgery, 1995, Volume: 37, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Anesthetics, Intravenous; Brain; Brain Edema; Drug Adm

1995

Other Studies

1 other study available for propylene glycol and Brain Swelling

ArticleYear
A case of propylene glycol toxic reaction associated with etomidate infusion.
    Archives of internal medicine, 1991, Volume: 151, Issue:11

    Topics: Acidosis, Lactic; Aged; Anticonvulsants; Brain Edema; Drug Therapy, Combination; Epilepsy, Tonic-Clo

1991