propylene glycol has been researched along with Alcoholism in 14 studies
Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "While some case reports indicate that high doses of propylene glycol (PG) may result in metabolic acidosis, there has been no large-scale study that evaluated the risk of metabolic acidosis in patients receiving PG-containing benzodiazepines for acute alcohol withdrawal." | 3.88 | Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model. ( Bodreau, C; Elbarbry, F; Farthing, K; Jahn, A, 2018) |
| "A new case of alcoholic ketoacidosis (AKA) is presented because of unusual clinical and biochemical features." | 1.32 | Major ketogenesis and the absence of an osmolar gap in an atypical case of alcoholic ketoacidosis. ( Azar, R; Dehon, B; Kim, I; Maisonneuve, N; Renom, G, 2003) |
| "The chronic administration of ethanol to pregnant rats at term results in the appearance of high concentrations of glycols such as 2,3-butanediol and 1,2-propanediol in their blood and urine." | 1.27 | The appearance of 2,3-butanediol in the chronic ethanol treated pregnant rat. ( Argilés, JM; López-Soriano, FJ; López-Tejero, D, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beauchamp, GA | 1 |
| Valento, M | 1 |
| Kim, J | 1 |
| Jahn, A | 1 |
| Bodreau, C | 1 |
| Farthing, K | 1 |
| Elbarbry, F | 1 |
| Yan, MT | 1 |
| Chau, T | 1 |
| Cheng, CJ | 1 |
| Lin, SH | 1 |
| Fung, EC | 1 |
| Crook, MA | 1 |
| Tuohy, KA | 1 |
| Nicholson, WJ | 1 |
| Schiffman, F | 1 |
| Renom, G | 1 |
| Maisonneuve, N | 1 |
| Kim, I | 1 |
| Dehon, B | 1 |
| Azar, R | 1 |
| Tsao, YT | 1 |
| Tsai, WC | 1 |
| Yang, SP | 1 |
| Rutstein, DD | 1 |
| Veech, RL | 5 |
| Nickerson, RJ | 1 |
| Felver, ME | 1 |
| Vernon, AA | 1 |
| Needham, LL | 1 |
| Kishore, P | 1 |
| Thacker, SB | 1 |
| Xu, D | 1 |
| Dhillon, AS | 1 |
| Abelmann, A | 1 |
| Croft, K | 1 |
| Peters, TJ | 1 |
| Palmer, TN | 1 |
| Casazza, JP | 4 |
| Song, BJ | 1 |
| Frietas, J | 1 |
| Stambuk, D | 1 |
| Morgan, MY | 1 |
| Gitomer, WL | 1 |
| López-Tejero, D | 1 |
| López-Soriano, FJ | 1 |
| Argilés, JM | 1 |
2 reviews available for propylene glycol and Alcoholism
| Article | Year |
|---|---|
Toxic alcohol ingestion: prompt recognition and management in the emergency department [digest].
Topics: 2-Propanol; Alcoholism; Antidotes; Diagnosis, Differential; Emergency Service, Hospital; Ethanol; Et | 2016 |
Short chain diol metabolism in human disease states.
Topics: Acetoin; Alcoholism; Butylene Glycols; Diabetic Ketoacidosis; Humans; Infant, Newborn; Infant, Prema | 1990 |
1 trial available for propylene glycol and Alcoholism
| Article | Year |
|---|---|
2,3-butanediol: an unusual metabolite in the serum of severely alcoholic men during acute intoxication.
Topics: Acute Disease; Alcoholic Intoxication; Alcoholism; Animals; Butylene Glycols; Clinical Trials as Top | 1983 |
11 other studies available for propylene glycol and Alcoholism
| Article | Year |
|---|---|
Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model.
Topics: Acid-Base Equilibrium; Acidosis; Alcoholism; Benzodiazepines; Diazepam; Female; Humans; Injections, | 2018 |
Hunting down a double gap metabolic acidosis.
Topics: Acidosis; Aged; Alcoholism; Fatal Outcome; Female; Humans; Kidney Failure, Chronic; Lorazepam; Pneum | 2010 |
Closing in on the gaps.
Topics: Acidosis; Aged; Alcoholism; Female; Humans; Kidney Failure, Chronic; Lorazepam; Pneumonia, Ventilato | 2010 |
Agitation by sedation.
Topics: Alcoholism; Antidotes; Chemistry, Pharmaceutical; Ethylene Glycol; Female; Fomepizole; Humans; Hypno | 2003 |
Major ketogenesis and the absence of an osmolar gap in an atypical case of alcoholic ketoacidosis.
Topics: Acidosis; Adult; Alcoholism; Female; Humans; Ketone Bodies; Ketosis; Osmolar Concentration; Propylen | 2003 |
A life-threatening double gap metabolic acidosis.
Topics: Acidosis; Alcoholism; Diagnosis, Differential; Humans; Hypnotics and Sedatives; Lorazepam; Male; Mid | 2008 |
Alcohol-related diols cause acute insulin resistance in vivo.
Topics: Alcoholism; Animals; Blood Glucose; Butylene Glycols; Diabetes Mellitus, Type 2; Glycogen; Insulin; | 1998 |
The measurement of 1,2-propanediol, D, L-2,3-butanediol and meso-2,3-butanediol in controls and alcoholic cirrhotics.
Topics: Alcoholism; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Butylene Glycols; Ethanol; | 1987 |
Metabolic pathways leading to diol formation.
Topics: Acetaldehyde; Acetoin; Alcoholism; Butylene Glycols; Chemical Phenomena; Chemistry; Ethanol; Humans; | 1987 |
The appearance of 2,3-butanediol in the chronic ethanol treated pregnant rat.
Topics: Alcoholism; Animals; Butylene Glycols; Ethanol; Female; Inactivation, Metabolic; Maternal-Fetal Exch | 1986 |
The production of 1,2-propanediol in ethanol treated rats.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans | 1985 |