propylene glycol has been researched along with Alcohol Abuse in 14 studies
Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.
| Excerpt | Relevance | Reference |
|---|---|---|
| "While some case reports indicate that high doses of propylene glycol (PG) may result in metabolic acidosis, there has been no large-scale study that evaluated the risk of metabolic acidosis in patients receiving PG-containing benzodiazepines for acute alcohol withdrawal." | 3.88 | Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model. ( Bodreau, C; Elbarbry, F; Farthing, K; Jahn, A, 2018) |
| "A new case of alcoholic ketoacidosis (AKA) is presented because of unusual clinical and biochemical features." | 1.32 | Major ketogenesis and the absence of an osmolar gap in an atypical case of alcoholic ketoacidosis. ( Azar, R; Dehon, B; Kim, I; Maisonneuve, N; Renom, G, 2003) |
| "The chronic administration of ethanol to pregnant rats at term results in the appearance of high concentrations of glycols such as 2,3-butanediol and 1,2-propanediol in their blood and urine." | 1.27 | The appearance of 2,3-butanediol in the chronic ethanol treated pregnant rat. ( Argilés, JM; López-Soriano, FJ; López-Tejero, D, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beauchamp, GA | 1 |
| Valento, M | 1 |
| Kim, J | 1 |
| Jahn, A | 1 |
| Bodreau, C | 1 |
| Farthing, K | 1 |
| Elbarbry, F | 1 |
| Yan, MT | 1 |
| Chau, T | 1 |
| Cheng, CJ | 1 |
| Lin, SH | 1 |
| Fung, EC | 1 |
| Crook, MA | 1 |
| Tuohy, KA | 1 |
| Nicholson, WJ | 1 |
| Schiffman, F | 1 |
| Renom, G | 1 |
| Maisonneuve, N | 1 |
| Kim, I | 1 |
| Dehon, B | 1 |
| Azar, R | 1 |
| Tsao, YT | 1 |
| Tsai, WC | 1 |
| Yang, SP | 1 |
| Rutstein, DD | 1 |
| Veech, RL | 5 |
| Nickerson, RJ | 1 |
| Felver, ME | 1 |
| Vernon, AA | 1 |
| Needham, LL | 1 |
| Kishore, P | 1 |
| Thacker, SB | 1 |
| Xu, D | 1 |
| Dhillon, AS | 1 |
| Abelmann, A | 1 |
| Croft, K | 1 |
| Peters, TJ | 1 |
| Palmer, TN | 1 |
| Casazza, JP | 4 |
| Song, BJ | 1 |
| Frietas, J | 1 |
| Stambuk, D | 1 |
| Morgan, MY | 1 |
| Gitomer, WL | 1 |
| López-Tejero, D | 1 |
| López-Soriano, FJ | 1 |
| Argilés, JM | 1 |
2 reviews available for propylene glycol and Alcohol Abuse
| Article | Year |
|---|---|
Toxic alcohol ingestion: prompt recognition and management in the emergency department [digest].
Topics: 2-Propanol; Alcoholism; Antidotes; Diagnosis, Differential; Emergency Service, Hospital; Ethanol; Et | 2016 |
Short chain diol metabolism in human disease states.
Topics: Acetoin; Alcoholism; Butylene Glycols; Diabetic Ketoacidosis; Humans; Infant, Newborn; Infant, Prema | 1990 |
1 trial available for propylene glycol and Alcohol Abuse
| Article | Year |
|---|---|
2,3-butanediol: an unusual metabolite in the serum of severely alcoholic men during acute intoxication.
Topics: Acute Disease; Alcoholic Intoxication; Alcoholism; Animals; Butylene Glycols; Clinical Trials as Top | 1983 |
11 other studies available for propylene glycol and Alcohol Abuse
| Article | Year |
|---|---|
Assessing Propylene Glycol Toxicity in Alcohol Withdrawal Patients Receiving Intravenous Benzodiazepines: A One-Compartment Pharmacokinetic Model.
Topics: Acid-Base Equilibrium; Acidosis; Alcoholism; Benzodiazepines; Diazepam; Female; Humans; Injections, | 2018 |
Hunting down a double gap metabolic acidosis.
Topics: Acidosis; Aged; Alcoholism; Fatal Outcome; Female; Humans; Kidney Failure, Chronic; Lorazepam; Pneum | 2010 |
Closing in on the gaps.
Topics: Acidosis; Aged; Alcoholism; Female; Humans; Kidney Failure, Chronic; Lorazepam; Pneumonia, Ventilato | 2010 |
Agitation by sedation.
Topics: Alcoholism; Antidotes; Chemistry, Pharmaceutical; Ethylene Glycol; Female; Fomepizole; Humans; Hypno | 2003 |
Major ketogenesis and the absence of an osmolar gap in an atypical case of alcoholic ketoacidosis.
Topics: Acidosis; Adult; Alcoholism; Female; Humans; Ketone Bodies; Ketosis; Osmolar Concentration; Propylen | 2003 |
A life-threatening double gap metabolic acidosis.
Topics: Acidosis; Alcoholism; Diagnosis, Differential; Humans; Hypnotics and Sedatives; Lorazepam; Male; Mid | 2008 |
Alcohol-related diols cause acute insulin resistance in vivo.
Topics: Alcoholism; Animals; Blood Glucose; Butylene Glycols; Diabetes Mellitus, Type 2; Glycogen; Insulin; | 1998 |
The measurement of 1,2-propanediol, D, L-2,3-butanediol and meso-2,3-butanediol in controls and alcoholic cirrhotics.
Topics: Alcoholism; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Butylene Glycols; Ethanol; | 1987 |
Metabolic pathways leading to diol formation.
Topics: Acetaldehyde; Acetoin; Alcoholism; Butylene Glycols; Chemical Phenomena; Chemistry; Ethanol; Humans; | 1987 |
The appearance of 2,3-butanediol in the chronic ethanol treated pregnant rat.
Topics: Alcoholism; Animals; Butylene Glycols; Ethanol; Female; Inactivation, Metabolic; Maternal-Fetal Exch | 1986 |
The production of 1,2-propanediol in ethanol treated rats.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans | 1985 |