Page last updated: 2024-10-20

propylene glycol and Acute Kidney Failure

propylene glycol has been researched along with Acute Kidney Failure in 6 studies

Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.

Research Excerpts

ExcerptRelevanceReference
" He received a high-dose lorazepam infusion for alcohol withdrawal during hospitalization and developed severe hyperosmolality, high anion gap metabolic acidosis, and acute kidney injury on his eighth day of hospitalization."7.74Acute kidney injury, hyperosmolality and metabolic acidosis associated with lorazepam. ( Graeber, C; Sullivan, A; Yusufzai, I; Zar, T, 2007)
" He received a high-dose lorazepam infusion for alcohol withdrawal during hospitalization and developed severe hyperosmolality, high anion gap metabolic acidosis, and acute kidney injury on his eighth day of hospitalization."3.74Acute kidney injury, hyperosmolality and metabolic acidosis associated with lorazepam. ( Graeber, C; Sullivan, A; Yusufzai, I; Zar, T, 2007)
" We believed that this represented an adverse effect that was probably related to the study drug and the study was stopped."2.68Propylene glycol toxicity following continuous etomidate infusion for the control of refractory cerebral edema. ( Aranda, M; Giannotta, SL; Levy, ML; Zelman, V, 1995)
"Propylene glycol is a solvent that is used in many oral, injectable, and topical medications."2.40Propylene glycol-induced proximal renal tubular cell injury. ( Al-Uzri, A; Boyer-Hassen, LV; Davenport, K; Johnson, MI; Theodorou, AA; Yorgin, PD, 1997)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nelsen, J1
Marraffa, JM1
Stork, CM1
Hodgman, M1
Holland, MG1
Jin, K1
Zar, T1
Yusufzai, I1
Sullivan, A1
Graeber, C1
Parmar, MS1
Levy, ML1
Aranda, M1
Zelman, V1
Giannotta, SL1
Yorgin, PD1
Theodorou, AA1
Al-Uzri, A1
Davenport, K1
Boyer-Hassen, LV1
Johnson, MI1

Reviews

1 review available for propylene glycol and Acute Kidney Failure

ArticleYear
Propylene glycol-induced proximal renal tubular cell injury.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1997, Volume: 30, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Humans; Kidney Tubules, Proximal; Male; Pharmaceutical Vehicles; Pr

1997

Trials

1 trial available for propylene glycol and Acute Kidney Failure

ArticleYear
Propylene glycol toxicity following continuous etomidate infusion for the control of refractory cerebral edema.
    Neurosurgery, 1995, Volume: 37, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Anesthetics, Intravenous; Brain; Brain Edema; Drug Adm

1995

Other Studies

4 other studies available for propylene glycol and Acute Kidney Failure

ArticleYear
An unusual case of dipropylene glycol toxicity.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:1

    Topics: Acute Kidney Injury; Humans; Nervous System Diseases; Propylene Glycol; Solvents

2009
Rhabdomyolysis, methemoglobinemia and acute kidney injury after indoxacarb poisoning.
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:3

    Topics: Acute Kidney Injury; Aged; Charcoal; Gastric Lavage; Glasgow Coma Scale; Humans; Insecticides; Intub

2012
Acute kidney injury, hyperosmolality and metabolic acidosis associated with lorazepam.
    Nature clinical practice. Nephrology, 2007, Volume: 3, Issue:9

    Topics: Acidosis; Acute Kidney Injury; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Drug Compounding; H

2007
Re: Acute kidney injury, hyperosmolality and metabolic acidosis associated with lorazepam.
    Nature clinical practice. Nephrology, 2007, Volume: 3, Issue:11

    Topics: Acidosis; Acute Kidney Injury; Anti-Anxiety Agents; Drug Compounding; Humans; Lorazepam; Osmolar Con

2007