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propylene glycol and Abnormalities, Drug-Induced

propylene glycol has been researched along with Abnormalities, Drug-Induced in 2 studies

Propylene Glycol: A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
propane-1,2-diol : The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
" Severe adverse effects have been noted with pharmaceutical formulations containing diethylene glycol monoethyl-ethers and this led to withdrawal from the French market."2.44[Hormone replacement therapy: toxicity of glycol ethers]. ( Biggi-Bernard, U; Descotes, J; Timour, Q, 2007)
" In these teratology studies, pregnant females were dosed during the period of organogenesis, followed by an assessment of fetal external, visceral, and skeletal development."1.36Assessment of hydroxypropyl methylcellulose, propylene glycol, polysorbate 80, and hydroxypropyl-β-cyclodextrin for use in developmental and reproductive toxicology studies. ( Enright, BP; Kopytek, SJ; McIntyre, BS; Thackaberry, EA; Treinen, KA, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Enright, BP1
McIntyre, BS1
Thackaberry, EA1
Treinen, KA1
Kopytek, SJ1
Timour, Q1
Biggi-Bernard, U1
Descotes, J1

Reviews

1 review available for propylene glycol and Abnormalities, Drug-Induced

ArticleYear
[Hormone replacement therapy: toxicity of glycol ethers].
    Journal de gynecologie, obstetrique et biologie de la reproduction, 2007, Volume: 36, Issue:1

    Topics: Abnormalities, Drug-Induced; Ethyl Ethers; Ethylene Glycol; Female; Fertility; Hormone Replacement T

2007

Other Studies

1 other study available for propylene glycol and Abnormalities, Drug-Induced

ArticleYear
Assessment of hydroxypropyl methylcellulose, propylene glycol, polysorbate 80, and hydroxypropyl-β-cyclodextrin for use in developmental and reproductive toxicology studies.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2010, Volume: 89, Issue:6

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Abnormalities, Drug-Induced; Animals; beta-Cyclodextrins; Dose-Re

2010