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propranolol and Ventricular Dysfunction, Left

propranolol has been researched along with Ventricular Dysfunction, Left in 14 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.

Research Excerpts

ExcerptRelevanceReference
" Segmental longitudinal (LS), radial (RS), and circumferential strain (CS) measurements by 3D-STI were compared with those by sonomicrometry at baseline and during pharmacological stress tests (dobutamine and propranolol infusion) and acute myocardial ischemia induced by coronary artery occlusion."3.75Validation of 3-dimensional speckle tracking imaging to quantify regional myocardial deformation. ( Aonuma, K; Enomoto, Y; Ishizu, T; Kawamura, R; Machino, T; Seo, Y; Sugimori, H; Yamamoto, M, 2009)
"The role of the adrenergic system on ventricular remodeling induced by cigarette smoking is unknown."1.35Effects of the administration of beta-blockers on ventricular remodeling induced by cigarette smoking in rats. ( Azevedo, PS; Campana, AO; Duarte, DR; Matsubara, BB; Matsubara, LS; Minicucci, MF; Oliveira, LC; Paiva, SA; Zornoff, LA, 2009)
"Ventricular arrhythmias and contractile dysfunction are the main causes of death in human heart failure (HF)."1.31Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness. ( Bers, DM; Li, L; Pogwizd, SM; Schlotthauer, K; Yuan, W, 2001)
"Propranolol treatment, which can induce cardiac depression in the normal heart, actually prevented cardiac dilation and the depressed left ventricular function characteristic of older TG mice, and abolished premature mortality."1.30Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse. ( Asai, K; Bishop, S; Geng, YJ; Homcy, CJ; Ishikawa, Y; Shannon, RP; Takagi, G; Vatner, DE; Vatner, SF; Wagner, TE; Yang, GP, 1999)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's10 (71.43)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duarte, DR1
Oliveira, LC1
Minicucci, MF1
Azevedo, PS1
Matsubara, BB1
Matsubara, LS1
Campana, AO1
Paiva, SA1
Zornoff, LA1
Seo, Y1
Ishizu, T1
Enomoto, Y1
Sugimori, H1
Yamamoto, M1
Machino, T1
Kawamura, R1
Aonuma, K1
Kajimoto, K1
Imai, T1
Minami, Y1
Kasanuki, H1
Evlakhov, VI1
Poyassov, IZ1
Mircoli, L1
Fedele, L1
Benetti, M1
Bolla, GB1
Radaelli, A1
Perlini, S1
Ferrari, AU1
Kyuma, M1
Tsuchihashi, K1
Shinshi, Y1
Hase, M1
Nakata, T1
Ooiwa, H1
Abiru, M1
Hikita, N1
Adachi, T1
Shoji, T1
Fujise, Y1
Shimamoto, K1
Duncker, DJ1
Haitsma, DB1
Liem, DA1
Verdouw, PD1
Merkus, D1
Simarro, E1
Rodríguez, MA1
Bayón, J1
Lastra, JA1
Prieto, P1
Suárez, G1
García Porrero, E1
Fernández, R1
Garrido, J1
Velasco, J1
Asai, K1
Yang, GP1
Geng, YJ1
Takagi, G1
Bishop, S1
Ishikawa, Y1
Shannon, RP1
Wagner, TE1
Vatner, DE1
Homcy, CJ1
Vatner, SF1
Knowles, JW1
Esposito, G1
Mao, L1
Hagaman, JR1
Fox, JE1
Smithies, O1
Rockman, HA1
Maeda, N1
Pogwizd, SM1
Schlotthauer, K1
Li, L1
Yuan, W1
Bers, DM1
Hart, CY1
Meyer, DM1
Tazelaar, HD1
Grande, JP1
Burnett , JC1
Housmans, PR1
Redfield, MM1
Takeichi, Y1
Yokota, M1
Iwase, M1
Izawa, H1
Nishizawa, T1
Ishiki, R1
Somura, F1
Nagata, K1
Isobe, S1
Noda, A1
Vasil'ev, AP1
Strel'tsova, NN1
Gorbunova, TIu1
Mal'tseva, IA1
Zykova, EL1

Trials

2 trials available for propranolol and Ventricular Dysfunction, Left

ArticleYear
[The effect of gallopamil and propranolol in patients with ischemic cardiopathy and moderate depression of ventricular function].
    Revista espanola de cardiologia, 1995, Volume: 48, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method

1995
[Antioxidant and antiarrhythmic activity of carvedilol in patients with ischemic heart disease. Comparison with anaprilin].
    Terapevticheskii arkhiv, 2001, Volume: 73, Issue:10

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Anti-Arrhythmia Agents; Antioxidants; Arrhythmias, Car

2001

Other Studies

12 other studies available for propranolol and Ventricular Dysfunction, Left

ArticleYear
Effects of the administration of beta-blockers on ventricular remodeling induced by cigarette smoking in rats.
    Arquivos brasileiros de cardiologia, 2009, Volume: 92, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Inhalation Exposure; Male; Models, Animal; Propranolol; Rats;

2009
Validation of 3-dimensional speckle tracking imaging to quantify regional myocardial deformation.
    Circulation. Cardiovascular imaging, 2009, Volume: 2, Issue:6

    Topics: Animals; Dobutamine; Echocardiography; Endocardium; Exercise Test; Image Enhancement; Imaging, Three

2009
Comparison of acute reduction in left ventricular outflow tract pressure gradient in obstructive hypertrophic cardiomyopathy by disopyramide versus pilsicainide versus cibenzoline.
    The American journal of cardiology, 2010, Nov-01, Volume: 106, Issue:9

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Disopyramide; Echocardiography, D

2010
Role of variations in pulmonary and cardiac hemodynamics in the reduction of the venous return during experimental ischemia of the left ventricular myocardium.
    Bulletin of experimental biology and medicine, 2012, Volume: 152, Issue:4

    Topics: Animals; Blood Pressure; Cats; Electric Stimulation; Heart; Heart Rate; Heart Ventricles; Lung; Myoc

2012
Preservation of the baroreceptor heart rate reflex by chemical sympathectomy in experimental heart failure.
    Circulation, 2002, Aug-13, Volume: 106, Issue:7

    Topics: Adrenergic beta-Antagonists; Animals; Baroreflex; Blood Pressure; Body Weight; Bradycardia; Catechol

2002
Effect of intravenous propranolol on left ventricular apical ballooning without coronary artery stenosis (ampulla cardiomyopathy): three cases.
    Circulation journal : official journal of the Japanese Circulation Society, 2002, Volume: 66, Issue:12

    Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Echocardiography; Electrocardiography; Female; Hu

2002
Exercise unmasks autonomic dysfunction in swine with a recent myocardial infarction.
    Cardiovascular research, 2005, Mar-01, Volume: 65, Issue:4

    Topics: Animals; Atropine; Autonomic Nervous System; Coronary Circulation; Disease Models, Animal; Exercise

2005
Beta-adrenergic receptor blockade arrests myocyte damage and preserves cardiac function in the transgenic G(salpha) mouse.
    The Journal of clinical investigation, 1999, Volume: 104, Issue:5

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiomyopathy, Dilated; Cy

1999
Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A-deficient mice.
    The Journal of clinical investigation, 2001, Volume: 107, Issue:8

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Enalapril; Furosemide; Guanylate Cyc

2001
Arrhythmogenesis and contractile dysfunction in heart failure: Roles of sodium-calcium exchange, inward rectifier potassium current, and residual beta-adrenergic responsiveness.
    Circulation research, 2001, Jun-08, Volume: 88, Issue:11

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Caffeine; Calc

2001
Load versus humoral activation in the genesis of early hypertensive heart disease.
    Circulation, 2001, Jul-10, Volume: 104, Issue:2

    Topics: Angiotensin II; Animals; Catecholamines; Diastole; Disease Models, Animal; Dogs; Endothelin-1; Heart

2001
Biphasic changes in left ventricular end-diastolic pressure during dynamic exercise in patients with nonobstructive hypertrophic cardiomyopathy.
    Journal of the American College of Cardiology, 2001, Volume: 38, Issue:2

    Topics: Adult; Aged; Blood Pressure; Cardiomyopathy, Hypertrophic; Catecholamines; Diastole; Electrocardiogr

2001