Page last updated: 2024-11-03

propranolol and Vascular Malformations

propranolol has been researched along with Vascular Malformations in 11 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Vascular Malformations: A spectrum of congenital, inherited, or acquired abnormalities in BLOOD VESSELS that can adversely affect the normal blood flow in ARTERIES or VEINS. Most are congenital defects such as abnormal communications between blood vessels (fistula), shunting of arterial blood directly into veins bypassing the CAPILLARIES (arteriovenous malformations), formation of large dilated blood blood-filled vessels (cavernous angioma), and swollen capillaries (capillary telangiectases). In rare cases, vascular malformations can result from trauma or diseases.

Research Excerpts

ExcerptRelevanceReference
"Propranolol is a nonselective β-adrenergic receptor (AR) blocker that has been the first-line therapy for problematic infantile hemangioma (IH), the most frequent childhood vascular tumor."8.12A transcription factor is the target of propranolol treatment in infantile hemangioma. ( Boscolo, E; Schrenk, S, 2022)
"Haemangiomas are the most common soft tissue tumours in infancy, occurring in approximately 5-10% of 1-year-old children."5.36Propranolol as a novel treatment for congenital visceral haemangioma. ( Cornette, L; Decaluwe, W; Van Geet, C; Vandelanotte, M; Vanlander, A, 2010)
"Propranolol is a nonselective β-adrenergic receptor (AR) blocker that has been the first-line therapy for problematic infantile hemangioma (IH), the most frequent childhood vascular tumor."4.12A transcription factor is the target of propranolol treatment in infantile hemangioma. ( Boscolo, E; Schrenk, S, 2022)
" The most common vascular tumor is infantile hemangioma, which treatment, when necessary, is propranolol."3.88[Benign aggressive vascular anomalies in children]. ( Boccara, O; Léauté-Labrèze, C; Maruani, A, 2018)
"Oral propranolol has become first-line intervention for problematic infantile hemangioma (IH) that is not amenable to topical or intralesional therapies."1.46Propranolol Treatment of Vascular Anomalies Other Than Infantile Hemangioma. ( Alomari, MH; Goss, JA; Greene, AK; Konczyk, DJ; Maclellan, RA, 2017)
"This case report describes propranolol treatment of vascular malformations such as Klippel-Trénaunay syndrome or Parkes-Weber syndrome in adults."1.42Successful treatment of a congenital extra-truncal vascular malformation by orally administered propranolol. ( Buecker, A; Janssen, E; Müller, CS; Pföhler, C; Vogt, T, 2015)
"Haemangiomas are the most common soft tissue tumours in infancy, occurring in approximately 5-10% of 1-year-old children."1.36Propranolol as a novel treatment for congenital visceral haemangioma. ( Cornette, L; Decaluwe, W; Van Geet, C; Vandelanotte, M; Vanlander, A, 2010)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (81.82)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Schrenk, S1
Boscolo, E1
Li, L1
Yang, B1
Wei, L1
Zhang, B1
Han, XF1
Xu, ZG1
Ma, L1
Díaz-Fontenla, F1
Castillo-Pradillo, M1
Díaz-Gómez, A1
Ibañez-Samaniego, L1
Gancedo, P1
Guzmán-de-Villoria, JA1
Fernández-García, P1
Bañares-Cañizares, R1
García-Martínez, R1
Goss, JA1
Konczyk, DJ1
Alomari, MH1
Maclellan, RA1
Greene, AK1
Boccara, O1
Maruani, A1
Léauté-Labrèze, C1
Pföhler, C1
Janssen, E1
Buecker, A1
Vogt, T1
Müller, CS1
Trenor, CC1
Slaughter, KA1
Chen, T1
Williams, E1
Vanlander, A1
Decaluwe, W1
Vandelanotte, M1
Van Geet, C1
Cornette, L1
Freshwater, MF1
Blei, F1

Reviews

3 reviews available for propranolol and Vascular Malformations

ArticleYear
Medical management of vascular anomalies.
    Seminars in cutaneous medicine and surgery, 2016, Volume: 35, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiogenesis Inhibitors; Bevacizumab; Clinical Decision-Making; Drug Th

2016
Vascular Lesions.
    Facial plastic surgery clinics of North America, 2016, Volume: 24, Issue:4

    Topics: Adrenergic beta-Antagonists; Combined Modality Therapy; Hemangioma; Humans; Plastic Surgery Procedur

2016
Medical management of vascular anomalies.
    Facial plastic surgery : FPS, 2012, Volume: 28, Issue:6

    Topics: Adrenergic beta-Antagonists; Hemangioendothelioma; Hemangioma; Humans; Kasabach-Merritt Syndrome; Pr

2012

Other Studies

8 other studies available for propranolol and Vascular Malformations

ArticleYear
A transcription factor is the target of propranolol treatment in infantile hemangioma.
    The Journal of clinical investigation, 2022, 02-01, Volume: 132, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Child; Hemangioma; Humans; Mice; Propranolol; SOXF Transcripti

2022
Application of the adenosine triphosphate sensitivity assay in infantile vascular anomalies.
    BMC pediatrics, 2020, 02-19, Volume: 20, Issue:1

    Topics: Adenosine Triphosphate; Hemangioma, Capillary; Humans; Infant; Propranolol; Vascular Malformations

2020
Refractory hepatic encephalopathy in a patient with hypothyroidism: Another element in ammonia metabolism.
    World journal of gastroenterology, 2017, Jul-28, Volume: 23, Issue:28

    Topics: Adrenergic beta-Antagonists; Alcoholism; Ammonia; Antithyroid Agents; Brain; Carbimazole; Diagnosis,

2017
Propranolol Treatment of Vascular Anomalies Other Than Infantile Hemangioma.
    The Journal of craniofacial surgery, 2017, Volume: 28, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Child; Child, Preschool; Diagnostic Errors; Female; Hemangioma,

2017
[Benign aggressive vascular anomalies in children].
    Bulletin du cancer, 2018, Volume: 105, Issue:6

    Topics: Adolescent; Adrenergic alpha-1 Receptor Antagonists; Arteriovenous Malformations; Child; Child, Pres

2018
Successful treatment of a congenital extra-truncal vascular malformation by orally administered propranolol.
    The Journal of dermatological treatment, 2015, Volume: 26, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Female; Humans; Klippel-Trenaunay-Weber Sy

2015
Propranolol as a novel treatment for congenital visceral haemangioma.
    Neonatology, 2010, Volume: 98, Issue:3

    Topics: Abdominal Neoplasms; Hemangioma; Humans; Infant, Newborn; Male; Propranolol; Umbilical Cord; Vascula

2010
Treatment of vascular anomalies of the upper extremity.
    The Journal of hand surgery, 2011, Volume: 36, Issue:2

    Topics: Child; Child, Preschool; Female; Hemangioma; Humans; Male; Propranolol; Radiography; Risk Assessment

2011