propranolol has been researched along with Varicose Veins in 22 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Varicose Veins: Enlarged and tortuous VEINS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A prospective randomized double-blind study was conducted to evaluate the efficacy of propranolol in patients with portal hypertension undergoing long-term endoscopic sclerotherapy (EST) for recurrent variceal bleeding." | 5.07 | A prospective randomized study to evaluate propranolol in patients undergoing long-term endoscopic sclerotherapy. ( Acharya, SK; Dasarathy, S; Pande, JN; Saksena, S, 1993) |
| " propranolol before initiating secondary prophylaxis for variceal bleeding is a useful tool in predicting the efficacy of non-selective beta-blockers." | 3.75 | Prognostic value of acute hemodynamic response to i.v. propranolol in patients with cirrhosis and portal hypertension. ( Abraldes, JG; Berzigotti, A; Bosch, J; García-Pagán, JC; La Mura, V; Raffa, S; Retto, O, 2009) |
| "220 patients with known esophageal varices on upper GI endoscopy and no previous history of GI bleed were randomized to group A (Carvedilol) and group B (Propranolol)." | 3.30 | Comparison of carvedilol and propranolol for primary prophylaxis of esophageal variceal bleed in cirrhotic patients. ( Aneeza Ilyas, -; Khalid Mahmud Khan, -; Maria, -; Muhammad Adnan Iqbal, -; Muhammad Farooq Hanif, -; Nooman Gilani, -; Raja Omer Fiaz, -, 2023) |
| "Such varices are often the source of difficult-to-treat recurrent or chronic bleeding." | 1.33 | Chronic stomal variceal bleeding after colonic surgery in patients with portal hypertension: efficacy of beta-blocking agents? ( Detry, RJ; Douala, HC; Druez, PM; Geubel, AP; Kartheuser, AH; Kartheuzer, AH; Noubibou, M, 2006) |
| "Ectopic intestinal varices are rarely responsible for lower gastrointestinal (GI) haemorrhage." | 1.32 | Ectopic intestinal varices as a rare cause of lower gastrointestinal haemorrhage. ( Ahmed, I; Alam, A; Alvi, A; Butt, AK; Khan, AA; Niazi, A; Sarwar, S; Shafqat, F; Tarique, S, 2003) |
| "Portal hypertension is due to cirrhosis in 10 cases and to metastases to the liver in 4 cases." | 1.28 | [Colostomy-induced varices in portal hypertension]. ( Damamme, B; Poilleux, J, 1992) |
| "Bleeding from ileal varices can be managed by either local control or portal vein decompression." | 1.27 | Variceal bleeding from an ileostomy stoma. ( Dunn, GD; McGrew, W; Wang, MM, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 5 (22.73) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, V | 1 |
| Kumar, P | 1 |
| Verma, N | 1 |
| Vijayvergiya, R | 1 |
| Singh, A | 1 |
| Bhalla, A | 1 |
| Hofer, BS | 1 |
| Simbrunner, B | 2 |
| Bauer, DJM | 1 |
| Paternostro, R | 2 |
| Schwabl, P | 1 |
| Scheiner, B | 2 |
| Semmler, G | 1 |
| Hartl, L | 2 |
| Jachs, M | 2 |
| Datterl, B | 1 |
| Staettermayer, AF | 1 |
| Trauner, M | 2 |
| Mandorfer, M | 2 |
| Reiberger, T | 2 |
| Bauer, D | 1 |
| Balcar, L | 1 |
| Hofer, B | 1 |
| Pfisterer, N | 1 |
| Schwarz, M | 1 |
| Stättermayer, AF | 1 |
| Pinter, M | 1 |
| Muhammad Farooq Hanif, - | 1 |
| Raja Omer Fiaz, - | 1 |
| Muhammad Adnan Iqbal, - | 1 |
| Aneeza Ilyas, - | 1 |
| Maria, - | 1 |
| Khalid Mahmud Khan, - | 1 |
| Nooman Gilani, - | 1 |
| Afaa, TJ | 1 |
| Amegan-Aho, KH | 1 |
| Richardson, E | 1 |
| Goka, B | 1 |
| Kalambokis, GN | 1 |
| Baltayiannis, G | 1 |
| Christou, L | 1 |
| Christodoulou, D | 1 |
| La Mura, V | 1 |
| Abraldes, JG | 2 |
| Raffa, S | 1 |
| Retto, O | 1 |
| Berzigotti, A | 1 |
| García-Pagán, JC | 3 |
| Bosch, J | 3 |
| Tarantino, I | 1 |
| Turnes, J | 1 |
| Rodés, J | 1 |
| Khan, AA | 1 |
| Sarwar, S | 1 |
| Alam, A | 1 |
| Butt, AK | 1 |
| Shafqat, F | 1 |
| Tarique, S | 1 |
| Ahmed, I | 1 |
| Alvi, A | 1 |
| Niazi, A | 1 |
| Garrido, A | 1 |
| Márquez, JL | 1 |
| Iglesias, A | 1 |
| Peiró, J | 1 |
| Grilo, I | 1 |
| Garzón, M | 1 |
| Noubibou, M | 1 |
| Douala, HC | 1 |
| Druez, PM | 1 |
| Kartheuser, AH | 1 |
| Kartheuzer, AH | 1 |
| Detry, RJ | 1 |
| Geubel, AP | 1 |
| van der Wouden, EJ | 1 |
| Westerveld, BD | 1 |
| Lebrec, D | 1 |
| Poynard, T | 1 |
| Hillon, P | 1 |
| Benhamou, JP | 1 |
| Sørensen, TI | 1 |
| Acharya, SK | 1 |
| Dasarathy, S | 1 |
| Saksena, S | 1 |
| Pande, JN | 1 |
| Groszmann, RJ | 1 |
| Orozco, H | 1 |
| Mercado, MA | 1 |
| Chan, C | 1 |
| Guillén-Navarro, E | 1 |
| López-Martínez, LM | 1 |
| Shah, SR | 1 |
| Escorsell, A | 1 |
| Bañares, R | 1 |
| Gilabert, R | 1 |
| Moitinho, E | 1 |
| Piqueras, B | 1 |
| Bru, C | 1 |
| Echenagusia, A | 1 |
| Granados, A | 1 |
| Poilleux, J | 1 |
| Damamme, B | 1 |
| Rikkers, LF | 1 |
| Wang, MM | 1 |
| McGrew, W | 1 |
| Dunn, GD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| To Study the Effect of Nonselective Beta Blockers in Advanced Stage Liver Disease With Ascites[NCT02649335] | Phase 3 | 190 participants (Actual) | Interventional | 2015-07-01 | Completed | ||
| VICIS - Vienna Cirrhosis Study[NCT03267615] | 10,000 participants (Anticipated) | Observational [Patient Registry] | 2017-02-01 | Recruiting | |||
| Pilot Study to Evaluate the Correlation Between ¹³C Methacetin Breath Test (MBT) and HVPG Measurement as a Tool for Identifying Responders to Portal Hypertension Therapy[NCT01851252] | Phase 1 | 19 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for propranolol and Varicose Veins
| Article | Year |
|---|---|
Failure of combined efforts: propranolol and sclerotherapy do not add up to the prevention of variceal bleeding.
Topics: Combined Modality Therapy; Hemorrhage; Humans; Propranolol; Sclerotherapy; Varicose Veins | 1993 |
New concepts of pathophysiology and treatment of portal hypertension.
Topics: Cardiology; Hemorrhage; Humans; Hypertension, Portal; Propranolol; Sclerotherapy; Varicose Veins; Va | 1990 |
6 trials available for propranolol and Varicose Veins
| Article | Year |
|---|---|
Propranolol vs. band ligation for primary prophylaxis of variceal hemorrhage in cirrhotic patients with ascites: a randomized controlled trial.
Topics: Acute Kidney Injury; Ascites; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; L | 2022 |
Comparison of carvedilol and propranolol for primary prophylaxis of esophageal variceal bleed in cirrhotic patients.
Topics: Adrenergic beta-Antagonists; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage | 2023 |
Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis: a controlled study.
Topics: Administration, Oral; Adult; Aged; Clinical Trials as Topic; Esophageal and Gastric Varices; Female; | 1981 |
A prospective randomized study to evaluate propranolol in patients undergoing long-term endoscopic sclerotherapy.
Topics: Administration, Oral; Adolescent; Adult; Combined Modality Therapy; Double-Blind Method; Endoscopy; | 1993 |
A comparative study of the elective treatment of variceal hemorrhage with beta-blockers, transendoscopic sclerotherapy, and surgery: a prospective, controlled, and randomized trial during 10 years.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Endoscopy; Female; Hemorrhage; Humans; Hyperte | 2000 |
TIPS versus drug therapy in preventing variceal rebleeding in advanced cirrhosis: a randomized controlled trial.
Topics: Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Female; Follow-Up Studies; Health Care | 2002 |
14 other studies available for propranolol and Varicose Veins
| Article | Year |
|---|---|
Acute hemodynamic response to propranolol predicts bleeding and nonbleeding decompensation in patients with cirrhosis.
Topics: Adult; Aged; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Live | 2022 |
Carvedilol Achieves Higher Hemodynamic Response and Lower Rebleeding Rates Than Propranolol in Secondary Prophylaxis.
Topics: Adrenergic beta-Antagonists; Carvedilol; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage | 2023 |
Diagnosis and management of extrahepatic oesophageal variceal bleed in children in a low resourced setting.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Esophageal and Gastric Varices; Female; | 2020 |
Red signs and not severity of cirrhosis should determine non-selective β-blocker treatment in Child-Pugh C cirrhosis with small varices: increased risk of hepatorenal syndrome and death beyond 6 months of propranolol use.
Topics: Adrenergic beta-Antagonists; Ascites; Child; Esophageal and Gastric Varices; Hepatorenal Syndrome; H | 2016 |
Prognostic value of acute hemodynamic response to i.v. propranolol in patients with cirrhosis and portal hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Cohort Studies; Female; Hemorrhage; Humans; Hypertension, Portal; | 2009 |
Hemodynamic response to pharmacological treatment of portal hypertension and long-term prognosis of cirrhosis.
Topics: Antihypertensive Agents; Ascites; Bacterial Infections; Cohort Studies; Drug Therapy, Combination; F | 2003 |
Ectopic intestinal varices as a rare cause of lower gastrointestinal haemorrhage.
Topics: Antihypertensive Agents; Endoscopy, Digestive System; Esophageal and Gastric Varices; Gastrointestin | 2003 |
[Hemorrhage due to peristomal ectopic varices: an infrequent complication of portal hypertension].
Topics: Cecal Neoplasms; Colonic Neoplasms; Diabetes Mellitus, Type 2; Duodenal Ulcer; Gastrointestinal Hemo | 2006 |
Chronic stomal variceal bleeding after colonic surgery in patients with portal hypertension: efficacy of beta-blocking agents?
Topics: Adrenergic beta-Antagonists; Aged; Chronic Disease; Colostomy; Gastrointestinal Hemorrhage; Humans; | 2006 |
A patient with diabetes mellitus and recurrent peristomal bleeding.
Topics: Aged; Antihypertensive Agents; Colostomy; Diabetes Mellitus, Type 2; Diagnosis, Differential; Electr | 2006 |
The hepatic venous pressure gradient: has the time arrived for its application in clinical practice?
Topics: Clinical Trials as Topic; Hemorrhage; Hepatic Veins; Humans; Liver Cirrhosis; Propranolol; Prospecti | 1996 |
Re: Orozco et al. A comparative study of the elective treatment of variceal hemorrhage with beta-blockers, transendoscopic sclerotherapy and surgery. A prospective, controlled, and randomized trial during 10 years. Ann Surg 2000; 232:216-9.
Topics: Adrenergic beta-Antagonists; Hemorrhage; Humans; Hypertension, Portal; Propranolol; Sclerotherapy; V | 2001 |
[Colostomy-induced varices in portal hypertension].
Topics: Aged; Colon; Colostomy; Female; Humans; Hypertension, Portal; Male; Middle Aged; Prognosis; Proprano | 1992 |
Variceal bleeding from an ileostomy stoma.
Topics: Hemorrhage; Humans; Hypertension, Portal; Ileostomy; Ileum; Ligation; Male; Middle Aged; Propranolol | 1985 |