Page last updated: 2024-11-03

propranolol and Torsade de Pointes

propranolol has been researched along with Torsade de Pointes in 13 studies

Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.

Research Excerpts

ExcerptRelevanceReference
"We tested whether the adenosine A1 receptor agonist, R-PIA, suppressed torsade de pointes (TdP) induced by the delayed rectifier potassium channel blocker clofilium."7.70Effects of adenosine A1-receptor activation on torsade de pointes in rabbits. ( Hou, CJ; Sung, RJ; Tan, HL, 1999)
"We tested whether the adenosine A1 receptor agonist, R-PIA, suppressed torsade de pointes (TdP) induced by the delayed rectifier potassium channel blocker clofilium."3.70Effects of adenosine A1-receptor activation on torsade de pointes in rabbits. ( Hou, CJ; Sung, RJ; Tan, HL, 1999)
"Torsade de pointes (TdP) syncopal episodes were almost invariably precipitated by emotional stress or menstruation in a 17-year-old girl."1.28Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes. ( Liu, WY; Zheng, LR; Zhou, JT, 1992)
"The treatment with propranolol was most effective."1.28[A case of congenital long QT syndrome associated with T wave alternans]. ( Aoki, T; Kakuta, Y; Kasai, A; Motoyasu, M; Nishikawa, H; Ono, N; Shimizu, Y; Unno, M; Yamakado, T; Yazu, T, 1992)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (69.23)18.2507
2000's1 (7.69)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mirams, GR1
Cui, Y1
Sher, A1
Fink, M1
Cooper, J1
Heath, BM1
McMahon, NC1
Gavaghan, DJ1
Noble, D1
Wiśniowska, B1
Mendyk, A1
Fijorek, K1
Glinka, A1
Polak, S1
Aziz, PF1
Tanel, RE1
Zelster, IJ1
Pass, RH1
Wieand, TS1
Vetter, VL1
Vogel, RL1
Shah, MJ1
Nakagawa, M1
Ooie, T1
Ou, B1
Ichinose, M1
Takahashi, N1
Hara, M1
Yonemochi, H1
Saikawa, T1
Kawade, M1
Ohe, T1
Kamiya, T1
Cieslinski, G1
Kadel, C1
Schräder, R1
Klepzig, H1
Noble, WE1
Chaudhuri, P1
Qazi, MA1
Kajinami, K1
Takekoshi, N1
Mabuchi, H1
Hsieh, MH1
Chen, SA1
Chiang, CE1
Tai, CT1
Lee, SH1
Wen, ZC1
Chang, MS1
Tan, HL1
Hou, CJ1
Sung, RJ1
Shimizu, W1
Antzelevitch, C1
Zhou, JT1
Zheng, LR1
Liu, WY1
Motoyasu, M1
Nishikawa, H1
Shimizu, Y1
Aoki, T1
Ono, N1
Unno, M1
Kakuta, Y1
Yazu, T1
Kasai, A1
Yamakado, T1

Other Studies

13 other studies available for propranolol and Torsade de Pointes

ArticleYear
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
    Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation;

2011
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computationa

2012
Congenital long QT syndrome and 2:1 atrioventricular block: an optimistic outcome in the current era.
    Heart rhythm, 2010, Volume: 7, Issue:6

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrioventricular Block; Child; Child, Preschool

2010
Gender differences in autonomic modulation of ventricular repolarization in humans.
    Journal of cardiovascular electrophysiology, 2005, Volume: 16, Issue:3

    Topics: Adult; Atropine; Autonomic Nervous System; Disease Susceptibility; Electrophysiologic Techniques, Ca

2005
Provocative testing and drug response in a patient with the long QT syndrome.
    British heart journal, 1995, Volume: 74, Issue:1

    Topics: Adolescent; Drug Therapy, Combination; Electrocardiography; Epinephrine; Female; Humans; Isoproteren

1995
[Implantable defibrillator in the long QT syndrome].
    Deutsche medizinische Wochenschrift (1946), 1995, Mar-03, Volume: 120, Issue:9

    Topics: Adult; Defibrillators, Implantable; Electrocardiography; Female; Humans; Long QT Syndrome; Propranol

1995
Idiopathic long q-t syndrome: brief case report and discussion.
    The West Virginia medical journal, 1994, Volume: 90, Issue:4

    Topics: Algorithms; Electrocardiography; Female; Humans; Long QT Syndrome; Middle Aged; Propranolol; Syncope

1994
Propranolol for probucol-induced QT prolongation with polymorphic ventricular tachycardia.
    Lancet (London, England), 1993, Jan-09, Volume: 341, Issue:8837

    Topics: Electrocardiography; Female; Humans; Long QT Syndrome; Middle Aged; Probucol; Propranolol; Torsades

1993
Drug-induced torsades de pointes in one patient with congenital long QT syndrome.
    International journal of cardiology, 1996, Apr-19, Volume: 54, Issue:1

    Topics: Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Astemizole; Cardiac Pacing, Artificial; Electr

1996
Effects of adenosine A1-receptor activation on torsade de pointes in rabbits.
    Cardiovascular drugs and therapy, 1999, Volume: 13, Issue:5

    Topics: Adenosine; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents;

1999
Differential response of transmural dispersion of repolarization and torsade de pointes to beta-adrenergic agonists and antagonists in three models of the long QT syndrome.
    Journal of electrocardiology, 1999, Volume: 32 Suppl

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Electrocardiography; Humans; Ion Cha

1999
Role of early afterdepolarization in familial long QTU syndrome and torsade de pointes.
    Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:11 Pt 2

    Topics: Action Potentials; Adolescent; Cardiac Pacing, Artificial; Epinephrine; Female; Heart Conduction Sys

1992
[A case of congenital long QT syndrome associated with T wave alternans].
    Kokyu to junkan. Respiration & circulation, 1992, Volume: 40, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Electrocardiography; Exercise Test; Female; Humans; Long QT Syndr

1992