propranolol has been researched along with Tetralogy of Fallot in 54 studies
Propranolol: A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.
propranolol : A propanolamine that is propan-2-ol substituted by a propan-2-ylamino group at position 1 and a naphthalen-1-yloxy group at position 3.
Tetralogy of Fallot: A combination of congenital heart defects consisting of four key features including VENTRICULAR SEPTAL DEFECTS; PULMONARY STENOSIS; RIGHT VENTRICULAR HYPERTROPHY; and a dextro-positioned AORTA. In this condition, blood from both ventricles (oxygen-rich and oxygen-poor) is pumped into the body often causing CYANOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the analytical micromethod using liquid chromatography for the quantification of propranolol in children submitted to surgery of tetralogy of Fallot (TLF)." | 7.74 | Propranolol plasma monitoring in children submitted to surgery of tetralogy of Fallot by a micromethod using high performance liquid chromatography. ( Auler, JO; Carmona, MJ; Galas, FR; Sanches, C; Santos, SR; Silva, AG, 2007) |
| "The aim of this study was to determine if preoperative propranolol therapy has a deleterious effect on postoperative variables in patients with tetralogy of Fallot." | 7.74 | Effect of preoperative use of propranolol on postoperative outcome in patients with tetralogy of Fallot. ( Atz, AM; Bandisode, VM; Bradley, SM; Crawford, FA; Graham, EM; Simsic, JM, 2008) |
| "When an 18 month old girl who had tetralogy of Fallot and episodes of severe cyanosis with loss of consciousness was treated with propranolol there was some improvement." | 7.67 | Propranolol induced bradycardia in tetralogy of Fallot. ( Chan, KC; Clark, DJ; Gibbs, JL, 1989) |
| "When propranolol is given to prevent hypoxaemic episodes in children with tetralogy of Fallot who are awaiting operation it is advisable to continue the treatment until shortly before the induction of anaesthesia." | 7.67 | Propranolol treatment in children with tetralogy of Fallot alters the response to isoprenaline after surgical repair. ( Barazzone, C; Berner, M; Dayer, P; Friedli, B; Jaccard, C; Oberhansli, I; Rouge, JC, 1988) |
| "Propranolol is a known medication used in patients with TOF to prevent and control hypercyanotic spells." | 5.35 | Propranolol: a new indication for an old drug in preventing postoperative junctional ectopic tachycardia after surgical repair of tetralogy of Fallot. ( Baslaim, GM; Kouatli, AA; Mahmoud, AB; Tantawy, AE, 2008) |
| "To evaluate the analytical micromethod using liquid chromatography for the quantification of propranolol in children submitted to surgery of tetralogy of Fallot (TLF)." | 3.74 | Propranolol plasma monitoring in children submitted to surgery of tetralogy of Fallot by a micromethod using high performance liquid chromatography. ( Auler, JO; Carmona, MJ; Galas, FR; Sanches, C; Santos, SR; Silva, AG, 2007) |
| "The aim of this study was to determine if preoperative propranolol therapy has a deleterious effect on postoperative variables in patients with tetralogy of Fallot." | 3.74 | Effect of preoperative use of propranolol on postoperative outcome in patients with tetralogy of Fallot. ( Atz, AM; Bandisode, VM; Bradley, SM; Crawford, FA; Graham, EM; Simsic, JM, 2008) |
| "When an 18 month old girl who had tetralogy of Fallot and episodes of severe cyanosis with loss of consciousness was treated with propranolol there was some improvement." | 3.67 | Propranolol induced bradycardia in tetralogy of Fallot. ( Chan, KC; Clark, DJ; Gibbs, JL, 1989) |
| "When propranolol is given to prevent hypoxaemic episodes in children with tetralogy of Fallot who are awaiting operation it is advisable to continue the treatment until shortly before the induction of anaesthesia." | 3.67 | Propranolol treatment in children with tetralogy of Fallot alters the response to isoprenaline after surgical repair. ( Barazzone, C; Berner, M; Dayer, P; Friedli, B; Jaccard, C; Oberhansli, I; Rouge, JC, 1988) |
| "Propranolol is a known medication used in patients with TOF to prevent and control hypercyanotic spells." | 1.35 | Propranolol: a new indication for an old drug in preventing postoperative junctional ectopic tachycardia after surgical repair of tetralogy of Fallot. ( Baslaim, GM; Kouatli, AA; Mahmoud, AB; Tantawy, AE, 2008) |
| "Chronic treatment of heart failure patients with beta-adrenoceptor antagonists leads to an up-regulation of cardiac beta-adrenoceptors, but in a subtype-selective fashion: beta 1-selective antagonists increase only cardiac beta 1-adrenoceptors, whereas non-selective antagonists increase both beta 1- and beta 2-adrenoceptors." | 1.28 | Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors. ( Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR, 1989) |
| "Ten had pulmonary valve stenosis, 4 had pulmonary valve stenosis plus ventricular septal defect, 8 had tetralogy of Fallot, and 2 had complex lesions." | 1.27 | Assessment of residual right ventricular outflow tract obstruction following surgery using the response to intravenous propranolol. ( de Leval, MR; Deanfield, JE; Karl, T; Macartney, FJ; Stark, J; Wensley, DF, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (85.19) | 18.7374 |
| 1990's | 1 (1.85) | 18.2507 |
| 2000's | 3 (5.56) | 29.6817 |
| 2010's | 2 (3.70) | 24.3611 |
| 2020's | 2 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Yutzey, KE | 1 |
| Voges, I | 1 |
| Krupickova, S | 1 |
| Bronzetti, G | 1 |
| Patrizi, A | 1 |
| Giacomini, F | 1 |
| Savoia, F | 1 |
| Raone, B | 1 |
| Brighenti, M | 1 |
| Bonvicini, M | 1 |
| Neri, I | 1 |
| Gargiulo, GD | 1 |
| Allford, MA | 1 |
| Brown, JL | 1 |
| Sanches, C | 1 |
| Galas, FR | 1 |
| Silva, AG | 1 |
| Carmona, MJ | 1 |
| Auler, JO | 1 |
| Santos, SR | 1 |
| Mahmoud, AB | 1 |
| Tantawy, AE | 1 |
| Kouatli, AA | 1 |
| Baslaim, GM | 1 |
| Graham, EM | 1 |
| Bandisode, VM | 1 |
| Bradley, SM | 1 |
| Crawford, FA | 1 |
| Simsic, JM | 1 |
| Atz, AM | 1 |
| Shah, PM | 1 |
| Kidd, L | 1 |
| Cumming, GR | 2 |
| Carr, W | 1 |
| Garson, A | 2 |
| Gorry, GA | 1 |
| McNamara, DG | 2 |
| Cooley, DA | 1 |
| Gillette, PC | 1 |
| Kugler, JD | 1 |
| Pinsky, WW | 1 |
| Cheatham, JP | 1 |
| Hofschire, PJ | 1 |
| Mooring, PK | 1 |
| Fleming, WH | 1 |
| Kam, CA | 1 |
| Schmaltz, AA | 1 |
| Leitriz, H | 1 |
| Apitz, J | 1 |
| Kemter, BE | 1 |
| Löser, H | 1 |
| Tjhen, KY | 1 |
| Eyster, GE | 1 |
| Anderson, LK | 1 |
| Sawyer, DC | 1 |
| Chaffee, A | 1 |
| Steinfeldt, B | 1 |
| Vijayaraghavan, G | 1 |
| Munsi, SC | 1 |
| Sukumar, IP | 1 |
| Cherian, G | 1 |
| Kozhevnikov, VA | 1 |
| Glonti, IG | 1 |
| Ivanov, AS | 1 |
| Charnaia, MA | 1 |
| Brodde, OE | 1 |
| Zerkowski, HR | 1 |
| Borst, HG | 1 |
| Maier, W | 1 |
| Michel, MC | 1 |
| Yadav, S | 1 |
| Khalil, A | 1 |
| Clark, DJ | 1 |
| Chan, KC | 1 |
| Gibbs, JL | 1 |
| Greeley, WJ | 1 |
| Stanley, TE | 1 |
| Ungerleider, RM | 1 |
| Kisslo, JA | 1 |
| Barazzone, C | 1 |
| Jaccard, C | 1 |
| Berner, M | 1 |
| Dayer, P | 1 |
| Rouge, JC | 1 |
| Oberhansli, I | 1 |
| Friedli, B | 1 |
| Wensley, DF | 1 |
| Karl, T | 1 |
| Deanfield, JE | 1 |
| de Leval, MR | 1 |
| Macartney, FJ | 1 |
| Stark, J | 1 |
| Ponce, FE | 1 |
| Williams, LC | 1 |
| Webb, HM | 1 |
| Riopel, DA | 1 |
| Hohn, AR | 1 |
| Lawrence, T | 1 |
| Frankl, WS | 1 |
| Furberg, CD | 1 |
| Ross, EM | 1 |
| Robertson, PG | 1 |
| Watson, H | 1 |
| Deptalla, H | 1 |
| Wiegershausen, B | 1 |
| Fitzgerald, JD | 1 |
| Loggie, JM | 1 |
| Van Maanen, EF | 1 |
| Viles, PH | 2 |
| Manning, JA | 1 |
| Dollery, CT | 1 |
| George, C | 1 |
| McBride, JT | 1 |
| McBride, MC | 1 |
| Feller, JM | 1 |
| Varkey, CC | 1 |
| Castan, R | 1 |
| Conn, RD | 1 |
| Ito, K | 1 |
| Furuse, A | 1 |
| Boku, S | 1 |
| Saigusa, M | 1 |
| Rasmussen, K | 1 |
| Martinez, J | 1 |
| Andrieu, P | 1 |
| Paczuszynski, H | 1 |
| Kaplinsky, E | 1 |
| Shem-Tov, A | 1 |
| Portuguese, D | 1 |
| Neufeld, HN | 1 |
| Hawker, RE | 1 |
| Celermajer, JM | 1 |
| Cartmill, TB | 1 |
| Asano, K | 1 |
| Sakashita, I | 1 |
| Aoki, E | 1 |
| Matsukawa, T | 1 |
| Asano, KI | 1 |
| Keck, EW | 1 |
| Brode, P | 1 |
| Herbert, WH | 1 |
| Farnsworth, PB | 1 |
| King, SB | 1 |
| Franch, RH | 1 |
| Wimmer, M | 1 |
| Müler, C | 1 |
| Dietzel, W | 1 |
| Schmitz, W | 1 |
| Wolter, H | 1 |
| Kato, H | 1 |
| Hirose, M | 1 |
| Yamaguchi, M | 1 |
| Yoshizawa, Y | 1 |
| Fukuda, H | 1 |
| Kimura, N | 1 |
| Toshima, H | 1 |
| Nakakura, S | 1 |
| Sasaki, K | 1 |
| Mizunoe, A | 1 |
| Eriksson, BO | 1 |
| Thorén, C | 1 |
| Zetterqvist, P | 1 |
| Gautier, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter Study for the Prevention of Post-Operative Cardiac Arrhythmias[NCT04234906] | Phase 4 | 870 participants (Anticipated) | Interventional | 2023-01-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for propranolol and Tetralogy of Fallot
| Article | Year |
|---|---|
A PHACES syndrome unmasked by propranolol interruption in a tetralogy of Fallot patient: case report and extensive review on new indications of beta blockers.
Topics: Abnormalities, Multiple; Adrenergic beta-Antagonists; Female; Humans; Infant; Propranolol; Tetralogy | 2014 |
Propranolol.
Topics: Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Child; Child, Preschool; Humans; Hypertension; I | 1989 |
Beta-adrenergic receptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Aortic Aneurysm; Aortic Valve; Arrhythmias | 1973 |
Beta-adrenergic receptor blocking drugs in hypertrophic cardiomyopathy, autonomically mediated cardiovascular functional disorders and Fallot's tetralogy.
Topics: Adrenergic beta-Antagonists; Alprenolol; Cardiomyopathy, Hypertrophic; Cardiovascular Diseases; Drug | 1974 |
[Beta-receptor-blocking agents and their current clinical significance].
Topics: Adrenal Gland Neoplasms; Amino Alcohols; Angina Pectoris; Anilides; Arrhythmias, Cardiac; Blood Pres | 1968 |
The autonomic nervous system and some aspects of the use of autonomic drugs in children. II.
Topics: Adrenergic beta-Antagonists; Aortic Valve Stenosis; Asthma; Autonomic Agents; Bronchitis; Cardiomyop | 1972 |
Recent advances in the treatment of congenital heart disease.
Topics: Age Factors; Arrhythmias, Cardiac; Child; Child, Preschool; Chlorothiazide; Diet, Sodium-Restricted; | 1974 |
Propranolol--ten years from introduction.
Topics: Angina Pectoris; Antihypertensive Agents; Anxiety; Aortic Aneurysm; Arrhythmias, Cardiac; Cardiomyop | 1974 |
1 trial available for propranolol and Tetralogy of Fallot
| Article | Year |
|---|---|
The therapeutic role of propranolol.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Cli | 1969 |
45 other studies available for propranolol and Tetralogy of Fallot
| Article | Year |
|---|---|
Cytokinesis, Beta-Blockers, and Congenital Heart Disease.
Topics: Adrenergic beta-Antagonists; Animals; Child; Cytokinesis; Heart; Humans; Infant; Mice; Mice, Transge | 2020 |
The role of propanolol in cardiomyocyte proliferation in tetralogy of Fallot - new market for an 'old' drug?
Topics: Cell Proliferation; Humans; Myocytes, Cardiac; Pharmaceutical Preparations; Propranolol; Tetralogy o | 2021 |
Case report: intraoperative hypoglycaemia in a child treated with propranolol following a short preoperative fast.
Topics: Adrenergic beta-Antagonists; Fasting; Humans; Hypoglycemia; Infant; Intraoperative Complications; Ma | 2011 |
Propranolol plasma monitoring in children submitted to surgery of tetralogy of Fallot by a micromethod using high performance liquid chromatography.
Topics: Child, Preschool; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Humans; Infant; Mal | 2007 |
Propranolol: a new indication for an old drug in preventing postoperative junctional ectopic tachycardia after surgical repair of tetralogy of Fallot.
Topics: Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Child, Preschool; Critical Care; Female; Follow | 2008 |
Effect of preoperative use of propranolol on postoperative outcome in patients with tetralogy of Fallot.
Topics: Adrenergic beta-Antagonists; Cardiotonic Agents; Child, Preschool; Drug Administration Schedule; Fem | 2008 |
Circulatory effects of propranolol in children with Fallot's tetralogy. Observations with isoproterenol infusion, exercise and crying.
Topics: Adolescent; Angiocardiography; Blood Flow Velocity; Blood Pressure; Cardiac Catheterization; Child; | 1967 |
Hemodynamic effects of propranolol in patients with Fallot's tetralogy.
Topics: Angiocardiography; Blood Pressure; Child, Preschool; Cyanosis; Dyspnea; Heart Rate; Humans; Infant; | 1967 |
The surgical decision in tetralogy of Fallot: weighing risks and benefits with decision analysis.
Topics: Hemodynamics; Humans; Infant; Life Expectancy; Palliative Care; Probability; Propranolol; Pulmonary | 1980 |
Propranolol: the preferred palliation for tetralogy of Fallot.
Topics: Cardiac Catheterization; Cineangiography; Dose-Response Relationship, Drug; Humans; Hypoxia; Infant; | 1981 |
Sustained ventricular tachycardia after repair of tetralogy of Fallot: new electrophysiologic findings.
Topics: Adolescent; Cardiac Catheterization; Cardiac Pacing, Artificial; Electrocardiography; Exercise Test; | 1983 |
Infundibular spasm in Fallot's tetralogy - an account and its management in anaesthesia.
Topics: Anesthesia, General; Anesthesia, Inhalation; Bradycardia; Child; Halothane; Humans; Hypoxia; Male; P | 1978 |
[Propranolol in Fallot's tetralogy: hemodynamic investigations and their clinical use (author's transl)].
Topics: Adolescent; Angiocardiography; Blood Pressure; Cardiac Catheterization; Child; Child, Preschool; Hea | 1977 |
Beta adrenergic blockade for management of tetralogy of Fallot in a dog.
Topics: Animals; Dog Diseases; Dogs; Female; Propranolol; Tetralogy of Fallot | 1976 |
Effect of beta adrenergic blocking agents in Tetralogy of Fallot.
Topics: Adolescent; Adult; Child; Female; Hemodynamics; Humans; Male; Physical Exertion; Propranolol; Tetral | 1976 |
[Approaches to prevention and treatment of arterial hypoxemia in the pre-perfusion period of radical correction of Fallot's tetrad].
Topics: Adolescent; Adult; Analgesia; Anesthesia, Intravenous; Child; Child, Preschool; Female; Humans; Hypn | 1992 |
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors.
Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure | 1989 |
Propranolol induced bradycardia in tetralogy of Fallot.
Topics: Bradycardia; Female; Humans; Infant; Propranolol; Syncope; Tetralogy of Fallot | 1989 |
Intraoperative hypoxemic spells in tetralogy of Fallot. An echocardiographic analysis of diagnosis and treatment.
Topics: Child, Preschool; Echocardiography, Doppler; Humans; Hypoxia; Infant; Intraoperative Complications; | 1989 |
Propranolol treatment in children with tetralogy of Fallot alters the response to isoprenaline after surgical repair.
Topics: Blood Pressure; Cardiopulmonary Bypass; Child; Child, Preschool; Dose-Response Relationship, Drug; D | 1988 |
Assessment of residual right ventricular outflow tract obstruction following surgery using the response to intravenous propranolol.
Topics: Blood Pressure; Cardiac Catheterization; Child; Child, Preschool; Dose-Response Relationship, Drug; | 1987 |
Propranolol palliation of tetralogy of Fallot: experience with long-term drug treatment in pediatric patients.
Topics: Blood Pressure; Bradycardia; Carbon Dioxide; Cardiac Catheterization; Child; Child, Preschool; Elect | 1973 |
Failure of oral propranolol to maintain relief from paroxysmal syncopal attacks in Fallot's tetralogy after its successful intravenous use.
Topics: Cardiac Surgical Procedures; Cyanosis; Dyspnea; Humans; Infant; Injections, Intravenous; Phonocardio | 1966 |
Hypoglycemia associated with propranolol.
Topics: Blood Glucose; Child, Preschool; Fasting; Glucose; Humans; Hypoglycemia; Male; Propranolol; Seizures | 1973 |
Danger of hypoglycaemia with use of propranolol.
Topics: Child; Fasting; Humans; Hypoglycemia; Propranolol; Tetralogy of Fallot | 1973 |
Propanalol in Fallot's tetralogy.
Topics: Adolescent; Child; Child, Preschool; Humans; Propranolol; Tetralogy of Fallot | 1973 |
[Clinical use of propranolol].
Topics: Alcoholism; Angina Pectoris; Aortic Aneurysm; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flut | 1974 |
Clinical usefulness of beta-adrenergic blocking agents.
Topics: Administration, Oral; Angina Pectoris; Aortic Aneurysm; Arrhythmias, Cardiac; Cardiomyopathy, Hypert | 1974 |
Hemodynamic effects of propranolol in patients with Fallot's tetralogy at rest.
Topics: Adolescent; Adult; Angiocardiography; Arteries; Blood Pressure; Child; Dye Dilution Technique; Femal | 1968 |
[Long term treatment with beta blockaders in tetralogy of Fallot].
Topics: Child; Child, Preschool; Humans; Infant; Long-Term Care; Propranolol; Tetralogy of Fallot | 1970 |
[Treatment of cyanosis attacks in Fallot's tetralogy (use of buffer substances and propranolol].
Topics: Acidosis; Angiocardiography; Buffers; Cyanosis; Female; Humans; Infant; Infant, Newborn; Male; Propr | 1970 |
[Propranolol in the management of tetralogy of Fallot].
Topics: Adolescent; Child; Child, Preschool; Cyanosis; Female; Humans; Infant; Male; Propranolol; Tetralogy | 1971 |
Detection and treatment of inapparent "blue spells" in the seriously ill patient with tetralogy of fallot.
Topics: Cyanosis; Humans; Injections, Intravenous; Male; Propranolol; Tetralogy of Fallot | 1971 |
Corrective surgery of Tetralogy of Fallot. The right ventricular outflow obstruction and its relief.
Topics: Angiocardiography; Blood Pressure; Heart Ventricles; Hemodynamics; Humans; Oxygen Consumption; Posto | 1966 |
Morphological and histochemical observations on right ventricular outflow tract of tetralogy of Fallot. With a brief reference to hemdynamic viewpoint. I.
Topics: Acid Phosphatase; Adolescent; Angiocardiography; Blood Pressure; Child; Child, Preschool; Glycogen; | 1969 |
Propranolol in tetralogy of Fallot.
Topics: Child; Child, Preschool; Dyspnea; Humans; Hypoxia; Preoperative Care; Propranolol; Tetralogy of Fall | 1970 |
[Beta-receptor blockade in Fallot's tetralogy. Decrease in hypoxia by propranolol].
Topics: Cardiac Catheterization; Child; Child, Preschool; Cineangiography; Cyanosis; Electrocardiography; Hu | 1970 |
Cyanotic episodes of tetralogy of Fallot. Pathogenesis and management.
Topics: Cardiac Catheterization; Child, Preschool; Cyanosis; Female; Humans; Phenothiazines; Propranolol; Sy | 1971 |
Production of increased right-to-left shunting by rapid heart rates in patients with tetralogy of Fallot.
Topics: Atropine; Blood Pressure; Cardiac Catheterization; Cardiac Volume; Child, Preschool; Cyanosis; Digox | 1971 |
[Propanolol in Fallot's tetralogy].
Topics: Child, Preschool; Cyanosis; Humans; Hypoxia; Infant; Pneumonia; Propranolol; Tetralogy of Fallot | 1971 |
[The use of beta-receptor blockade in heart surgery].
Topics: Adult; Child; Electric Countershock; Electrocardiography; Female; Humans; Injections, Intravenous; M | 1967 |
[Hemodynamic effects of isoproterenol and propranolol in tetralogy of Fallot--development of anoxic spells and its treatment].
Topics: Adolescent; Angiocardiography; Blood Pressure; Child; Child, Preschool; Cyanosis; Electrocardiograph | 1967 |
Hemodynamic effects of beta-adrenergic blockade in patients with congenital heart disease.
Topics: Adolescent; Adult; Angiocardiography; Blood Pressure; Cardiac Catheterization; Child; Child, Prescho | 1968 |
Long-term treatment with propranolol in selected cases of Fallot's tetralogy.
Topics: Child; Child, Preschool; Cyanosis; Dyspnea; Female; Humans; Male; Phonocardiography; Propranolol; Te | 1969 |
[Propranolol in the disorders of the tetralogy of Fallot].
Topics: Cyanosis; Heart Septal Defects, Ventricular; Humans; Infant; Infant, Newborn; Propranolol; Pulmonary | 1969 |